1VRQ
Crystal Structure of Heterotetrameric Sarcosine Oxidase from Corynebacterium sp. U-96 in complex with Folinic Acid
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0008115 | molecular_function | sarcosine oxidase activity |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0046653 | biological_process | tetrahydrofolate metabolic process |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0008115 | molecular_function | sarcosine oxidase activity |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0046653 | biological_process | tetrahydrofolate metabolic process |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0008115 | molecular_function | sarcosine oxidase activity |
| C | 0016491 | molecular_function | oxidoreductase activity |
| C | 1901053 | biological_process | sarcosine catabolic process |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0008115 | molecular_function | sarcosine oxidase activity |
| D | 0016491 | molecular_function | oxidoreductase activity |
| D | 0046653 | biological_process | tetrahydrofolate metabolic process |
| D | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN D 1006 |
| Chain | Residue |
| D | CYS6 |
| D | CYS9 |
| D | HIS59 |
| D | CYS63 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 C 2001 |
| Chain | Residue |
| A | GLN30 |
| C | ALA25 |
| C | GLY26 |
| C | GLU27 |
| C | ARG28 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 A 2002 |
| Chain | Residue |
| A | ARG574 |
| A | ALA696 |
| A | ALA697 |
| A | THR722 |
| A | HOH3682 |
| A | HOH4041 |
| A | HOH4141 |
| C | ARG176 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 2003 |
| Chain | Residue |
| A | LYS446 |
| A | ILE447 |
| A | HOH3533 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 B 2004 |
| Chain | Residue |
| B | ASN13 |
| B | ASN14 |
| B | HOH3320 |
| site_id | AC6 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 D 2005 |
| Chain | Residue |
| A | THR709 |
| D | HIS24 |
| D | ASN68 |
| D | ALA84 |
| D | GLY85 |
| D | HOH3297 |
| D | HOH3794 |
| D | HOH4008 |
| site_id | AC7 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 B 2006 |
| Chain | Residue |
| B | HIS7 |
| B | LYS171 |
| B | HIS174 |
| B | LYS277 |
| B | HOH3358 |
| B | HOH3710 |
| B | HOH3942 |
| B | HOH4011 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 A 2007 |
| Chain | Residue |
| A | ASN651 |
| A | GLY652 |
| A | SER847 |
| A | LEU849 |
| A | HOH3539 |
| A | HOH3781 |
| A | HOH3807 |
| site_id | AC9 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 A 2008 |
| Chain | Residue |
| A | ARG929 |
| A | ASN930 |
| site_id | BC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 2009 |
| Chain | Residue |
| A | GLN217 |
| A | ARG219 |
| A | HOH3107 |
| C | VAL199 |
| site_id | BC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 A 2010 |
| Chain | Residue |
| A | SER1 |
| A | LYS285 |
| A | LEU349 |
| A | SER350 |
| A | ALA371 |
| A | ASP372 |
| A | HOH4103 |
| site_id | BC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 2011 |
| Chain | Residue |
| A | GLN489 |
| A | ASP493 |
| A | TYR511 |
| A | THR512 |
| B | HIS7 |
| site_id | BC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 D 2012 |
| Chain | Residue |
| C | ARG119 |
| C | THR153 |
| D | SER60 |
| D | GLY62 |
| D | HOH3782 |
| site_id | BC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 A 2013 |
| Chain | Residue |
| A | SER7 |
| A | ALA8 |
| site_id | BC6 |
| Number of Residues | 36 |
| Details | BINDING SITE FOR RESIDUE FAD B 1001 |
| Chain | Residue |
| B | GLY356 |
| B | PHE357 |
| B | LYS358 |
| B | DMG1005 |
| B | HOH3007 |
| B | HOH3159 |
| B | HOH3577 |
| B | HOH3698 |
| B | VAL26 |
| B | GLY27 |
| B | GLY29 |
| B | GLY30 |
| B | HIS31 |
| B | LEU51 |
| B | GLU52 |
| B | LYS53 |
| B | GLY59 |
| B | ASN60 |
| B | MET61 |
| B | ARG63 |
| B | ASN64 |
| B | THR65 |
| B | THR66 |
| B | ILE67 |
| B | CYS194 |
| B | VAL196 |
| B | ALA224 |
| B | GLY225 |
| B | ALA226 |
| B | HIS228 |
| B | LEU232 |
| B | LEU247 |
| B | ALA249 |
| B | GLY353 |
| B | THR354 |
| B | GLY355 |
| site_id | BC7 |
| Number of Residues | 29 |
| Details | BINDING SITE FOR RESIDUE NAD A 1002 |
| Chain | Residue |
| A | GLY134 |
| A | GLY136 |
| A | PRO137 |
| A | ALA138 |
| A | ASP157 |
| A | GLU158 |
| A | ARG159 |
| A | GLY164 |
| A | THR165 |
| A | THR202 |
| A | VAL204 |
| A | ALA247 |
| A | THR248 |
| A | ALA249 |
| A | SER294 |
| A | PHE380 |
| A | GLY416 |
| A | ALA417 |
| A | LEU422 |
| A | ASP423 |
| A | THR424 |
| A | TYR553 |
| A | HOH3003 |
| A | HOH3005 |
| A | HOH3019 |
| A | HOH3039 |
| A | HOH3191 |
| A | HOH3212 |
| A | HOH3540 |
| site_id | BC8 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE FON A 1003 |
| Chain | Residue |
| A | LEU631 |
| A | TYR663 |
| A | ASP676 |
| A | GLY677 |
| A | HIS690 |
| A | THR691 |
| A | ILE774 |
| A | SER775 |
| A | PHE776 |
| A | GLU783 |
| A | LYS822 |
| A | PHE824 |
| A | TRP844 |
| site_id | BC9 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE FMN B 1004 |
| Chain | Residue |
| A | LYS509 |
| A | ARG510 |
| A | THR516 |
| A | GLN520 |
| A | THR548 |
| A | ARG550 |
| B | ALA62 |
| B | ARG63 |
| B | ASN64 |
| B | THR66 |
| B | HIS172 |
| B | VAL251 |
| B | LYS277 |
| B | GLU279 |
| B | ARG322 |
| B | TRP324 |
| B | HOH3042 |
| B | HOH3059 |
| B | HOH3084 |
| B | HOH3295 |
| B | HOH3449 |
| B | HOH3520 |
| site_id | CC1 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE DMG B 1005 |
| Chain | Residue |
| B | THR65 |
| B | ILE67 |
| B | ARG69 |
| B | MET264 |
| B | THR354 |
| B | LYS358 |
| B | ALA401 |
| B | FAD1001 |
| B | HOH3224 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 24 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"15946648","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"20675294","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1VRQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1X31","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3AD7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3AD8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3AD9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3ADA","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"15946648","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"1VRQ","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Tele-8alpha-FMN histidine","evidences":[{"source":"PubMed","id":"11902668","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"20675294","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3AD7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3AD8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3AD9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3ADA","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1c0k |
| Chain | Residue | Details |
| B | LEU385 |
