1VR3
Crystal structure of Acireductone dioxygenase (13543033) from Mus musculus at 2.06 A resolution
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005506 | molecular_function | iron ion binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0005654 | cellular_component | nucleoplasm |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0006555 | biological_process | methionine metabolic process |
| A | 0008652 | biological_process | amino acid biosynthetic process |
| A | 0009086 | biological_process | methionine biosynthetic process |
| A | 0010308 | molecular_function | acireductone dioxygenase (Ni2+-requiring) activity |
| A | 0010309 | molecular_function | acireductone dioxygenase [iron(II)-requiring] activity |
| A | 0016151 | molecular_function | nickel cation binding |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0019509 | biological_process | L-methionine salvage from methylthioadenosine |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0051213 | molecular_function | dioxygenase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NI A 200 |
| Chain | Residue |
| A | HIS88 |
| A | HIS90 |
| A | GLU94 |
| A | HIS133 |
| A | UNL201 |
| site_id | AC2 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE UNL A 201 |
| Chain | Residue |
| A | ARG96 |
| A | HIS133 |
| A | ARG147 |
| A | NI200 |
| A | HOH235 |
| A | HOH365 |
| A | PHE84 |
| A | HIS88 |
| A | HIS90 |
| A | GLU94 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE IPA A 202 |
| Chain | Residue |
| A | LYS57 |
| A | ASN60 |
| A | ARG108 |
| A | HOH317 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"16783794","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26858196","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1VR3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5I8S","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5I8T","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5I91","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5I93","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
