1VPX
Crystal structure of Transaldolase (EC 2.2.1.2) (TM0295) from Thermotoga maritima at 2.40 A resolution
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004801 | molecular_function | transaldolase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005975 | biological_process | carbohydrate metabolic process |
| A | 0006098 | biological_process | pentose-phosphate shunt |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016832 | molecular_function | aldehyde-lyase activity |
| B | 0004801 | molecular_function | transaldolase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005975 | biological_process | carbohydrate metabolic process |
| B | 0006098 | biological_process | pentose-phosphate shunt |
| B | 0016740 | molecular_function | transferase activity |
| B | 0016832 | molecular_function | aldehyde-lyase activity |
| C | 0004801 | molecular_function | transaldolase activity |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0005975 | biological_process | carbohydrate metabolic process |
| C | 0006098 | biological_process | pentose-phosphate shunt |
| C | 0016740 | molecular_function | transferase activity |
| C | 0016832 | molecular_function | aldehyde-lyase activity |
| D | 0004801 | molecular_function | transaldolase activity |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0005975 | biological_process | carbohydrate metabolic process |
| D | 0006098 | biological_process | pentose-phosphate shunt |
| D | 0016740 | molecular_function | transferase activity |
| D | 0016832 | molecular_function | aldehyde-lyase activity |
| E | 0004801 | molecular_function | transaldolase activity |
| E | 0005737 | cellular_component | cytoplasm |
| E | 0005975 | biological_process | carbohydrate metabolic process |
| E | 0006098 | biological_process | pentose-phosphate shunt |
| E | 0016740 | molecular_function | transferase activity |
| E | 0016832 | molecular_function | aldehyde-lyase activity |
| F | 0004801 | molecular_function | transaldolase activity |
| F | 0005737 | cellular_component | cytoplasm |
| F | 0005975 | biological_process | carbohydrate metabolic process |
| F | 0006098 | biological_process | pentose-phosphate shunt |
| F | 0016740 | molecular_function | transferase activity |
| F | 0016832 | molecular_function | aldehyde-lyase activity |
| G | 0004801 | molecular_function | transaldolase activity |
| G | 0005737 | cellular_component | cytoplasm |
| G | 0005975 | biological_process | carbohydrate metabolic process |
| G | 0006098 | biological_process | pentose-phosphate shunt |
| G | 0016740 | molecular_function | transferase activity |
| G | 0016832 | molecular_function | aldehyde-lyase activity |
| H | 0004801 | molecular_function | transaldolase activity |
| H | 0005737 | cellular_component | cytoplasm |
| H | 0005975 | biological_process | carbohydrate metabolic process |
| H | 0006098 | biological_process | pentose-phosphate shunt |
| H | 0016740 | molecular_function | transferase activity |
| H | 0016832 | molecular_function | aldehyde-lyase activity |
| I | 0004801 | molecular_function | transaldolase activity |
| I | 0005737 | cellular_component | cytoplasm |
| I | 0005975 | biological_process | carbohydrate metabolic process |
| I | 0006098 | biological_process | pentose-phosphate shunt |
| I | 0016740 | molecular_function | transferase activity |
| I | 0016832 | molecular_function | aldehyde-lyase activity |
| J | 0004801 | molecular_function | transaldolase activity |
| J | 0005737 | cellular_component | cytoplasm |
| J | 0005975 | biological_process | carbohydrate metabolic process |
| J | 0006098 | biological_process | pentose-phosphate shunt |
| J | 0016740 | molecular_function | transferase activity |
| J | 0016832 | molecular_function | aldehyde-lyase activity |
| K | 0004801 | molecular_function | transaldolase activity |
| K | 0005737 | cellular_component | cytoplasm |
| K | 0005975 | biological_process | carbohydrate metabolic process |
| K | 0006098 | biological_process | pentose-phosphate shunt |
| K | 0016740 | molecular_function | transferase activity |
| K | 0016832 | molecular_function | aldehyde-lyase activity |
| L | 0004801 | molecular_function | transaldolase activity |
| L | 0005737 | cellular_component | cytoplasm |
| L | 0005975 | biological_process | carbohydrate metabolic process |
| L | 0006098 | biological_process | pentose-phosphate shunt |
| L | 0016740 | molecular_function | transferase activity |
| L | 0016832 | molecular_function | aldehyde-lyase activity |
| M | 0004801 | molecular_function | transaldolase activity |
| M | 0005737 | cellular_component | cytoplasm |
| M | 0005975 | biological_process | carbohydrate metabolic process |
| M | 0006098 | biological_process | pentose-phosphate shunt |
| M | 0016740 | molecular_function | transferase activity |
| M | 0016832 | molecular_function | aldehyde-lyase activity |
| N | 0004801 | molecular_function | transaldolase activity |
| N | 0005737 | cellular_component | cytoplasm |
| N | 0005975 | biological_process | carbohydrate metabolic process |
| N | 0006098 | biological_process | pentose-phosphate shunt |
| N | 0016740 | molecular_function | transferase activity |
| N | 0016832 | molecular_function | aldehyde-lyase activity |
| O | 0004801 | molecular_function | transaldolase activity |
| O | 0005737 | cellular_component | cytoplasm |
| O | 0005975 | biological_process | carbohydrate metabolic process |
| O | 0006098 | biological_process | pentose-phosphate shunt |
| O | 0016740 | molecular_function | transferase activity |
| O | 0016832 | molecular_function | aldehyde-lyase activity |
| P | 0004801 | molecular_function | transaldolase activity |
| P | 0005737 | cellular_component | cytoplasm |
| P | 0005975 | biological_process | carbohydrate metabolic process |
| P | 0006098 | biological_process | pentose-phosphate shunt |
| P | 0016740 | molecular_function | transferase activity |
| P | 0016832 | molecular_function | aldehyde-lyase activity |
| Q | 0004801 | molecular_function | transaldolase activity |
| Q | 0005737 | cellular_component | cytoplasm |
| Q | 0005975 | biological_process | carbohydrate metabolic process |
| Q | 0006098 | biological_process | pentose-phosphate shunt |
| Q | 0016740 | molecular_function | transferase activity |
| Q | 0016832 | molecular_function | aldehyde-lyase activity |
| R | 0004801 | molecular_function | transaldolase activity |
| R | 0005737 | cellular_component | cytoplasm |
| R | 0005975 | biological_process | carbohydrate metabolic process |
| R | 0006098 | biological_process | pentose-phosphate shunt |
| R | 0016740 | molecular_function | transferase activity |
| R | 0016832 | molecular_function | aldehyde-lyase activity |
| S | 0004801 | molecular_function | transaldolase activity |
| S | 0005737 | cellular_component | cytoplasm |
| S | 0005975 | biological_process | carbohydrate metabolic process |
| S | 0006098 | biological_process | pentose-phosphate shunt |
| S | 0016740 | molecular_function | transferase activity |
| S | 0016832 | molecular_function | aldehyde-lyase activity |
| T | 0004801 | molecular_function | transaldolase activity |
| T | 0005737 | cellular_component | cytoplasm |
| T | 0005975 | biological_process | carbohydrate metabolic process |
| T | 0006098 | biological_process | pentose-phosphate shunt |
| T | 0016740 | molecular_function | transferase activity |
| T | 0016832 | molecular_function | aldehyde-lyase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 O 219 |
| Chain | Residue |
| O | LYS2 |
| O | ASP23 |
| O | LYS51 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL B 219 |
| Chain | Residue |
| B | VAL148 |
| B | TYR151 |
| B | ASN152 |
| B | PHE156 |
| B | THR158 |
| B | ASP180 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL C 219 |
| Chain | Residue |
| C | TYR151 |
| C | ASN152 |
| C | PHE156 |
| C | THR158 |
| C | ASP180 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL R 219 |
| Chain | Residue |
| R | TYR151 |
| R | PHE156 |
| R | GLU157 |
| R | THR158 |
| R | GLU159 |
| R | ASP180 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL S 219 |
| Chain | Residue |
| S | ASN152 |
| S | PHE156 |
| S | THR158 |
| S | ASP180 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL K 219 |
| Chain | Residue |
| K | TYR151 |
| K | ASN152 |
| K | GLY155 |
| K | PHE156 |
| K | THR158 |
| K | ASP180 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL N 219 |
| Chain | Residue |
| N | TYR151 |
| N | PHE156 |
| N | THR158 |
| N | ASP180 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL O 220 |
| Chain | Residue |
| O | TYR151 |
| O | GLY155 |
| O | PHE156 |
| O | THR158 |
| O | ASP180 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL F 219 |
| Chain | Residue |
| F | TYR151 |
| F | ASN152 |
| F | PHE156 |
| F | THR158 |
| F | ASP180 |
| site_id | BC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL G 219 |
| Chain | Residue |
| G | VAL148 |
| G | TYR151 |
| G | ASN152 |
| G | PHE156 |
| G | THR158 |
| G | ASP180 |
| site_id | BC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL H 219 |
| Chain | Residue |
| H | VAL148 |
| H | TYR151 |
| H | ASN152 |
| H | PHE156 |
| H | THR158 |
| H | ILE160 |
| H | ASP180 |
| site_id | BC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL I 219 |
| Chain | Residue |
| I | TYR151 |
| I | ASN152 |
| I | PHE156 |
| I | THR158 |
| I | ASP180 |
| site_id | BC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL J 219 |
| Chain | Residue |
| J | TYR151 |
| J | ASN152 |
| J | PHE156 |
| J | THR158 |
| J | ASP180 |
| site_id | BC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A 219 |
| Chain | Residue |
| A | VAL148 |
| A | TYR151 |
| A | ASN152 |
| A | PHE156 |
| A | THR158 |
| A | ASP180 |
| A | HOH221 |
| site_id | BC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL D 219 |
| Chain | Residue |
| D | TYR151 |
| D | ASN152 |
| D | PHE156 |
| D | THR158 |
| D | ILE160 |
| D | ASP180 |
| site_id | BC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL E 219 |
| Chain | Residue |
| E | TYR151 |
| E | PHE156 |
| E | THR158 |
| E | ASP180 |
| site_id | BC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL P 219 |
| Chain | Residue |
| P | TYR151 |
| P | ASN152 |
| P | PHE156 |
| P | GLU157 |
| P | THR158 |
| P | ASP180 |
| site_id | BC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL Q 219 |
| Chain | Residue |
| Q | TYR151 |
| Q | ASN152 |
| Q | PHE156 |
| Q | THR158 |
| Q | ASP180 |
| site_id | CC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL T 219 |
| Chain | Residue |
| T | ASP180 |
| T | TYR151 |
| T | GLY155 |
| T | PHE156 |
| T | THR158 |
| site_id | CC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL L 219 |
| Chain | Residue |
| L | TYR151 |
| L | ASN152 |
| L | PHE156 |
| L | GLU157 |
| L | THR158 |
| L | GLU159 |
| L | ASP180 |
| site_id | CC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL M 219 |
| Chain | Residue |
| M | TYR151 |
| M | ASN152 |
| M | PHE156 |
| M | THR158 |
| M | ASP180 |
| site_id | CC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL P 220 |
| Chain | Residue |
| P | ASP23 |
| P | VAL50 |
| P | LYS51 |
| P | GLY52 |
Functional Information from PROSITE/UniProt
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 20 |
| Details | Active site: {"description":"Schiff-base intermediate with substrate","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1onr |
| Chain | Residue | Details |
| A | ASP6 | |
| A | LYS83 | |
| A | GLU57 |
| site_id | CSA10 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1onr |
| Chain | Residue | Details |
| J | ASP6 | |
| J | LYS83 | |
| J | GLU57 |
| site_id | CSA11 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1onr |
| Chain | Residue | Details |
| K | ASP6 | |
| K | LYS83 | |
| K | GLU57 |
| site_id | CSA12 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1onr |
| Chain | Residue | Details |
| L | ASP6 | |
| L | LYS83 | |
| L | GLU57 |
| site_id | CSA13 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1onr |
| Chain | Residue | Details |
| M | ASP6 | |
| M | LYS83 | |
| M | GLU57 |
| site_id | CSA14 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1onr |
| Chain | Residue | Details |
| N | ASP6 | |
| N | LYS83 | |
| N | GLU57 |
| site_id | CSA15 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1onr |
| Chain | Residue | Details |
| O | ASP6 | |
| O | LYS83 | |
| O | GLU57 |
| site_id | CSA16 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1onr |
| Chain | Residue | Details |
| P | ASP6 | |
| P | LYS83 | |
| P | GLU57 |
| site_id | CSA17 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1onr |
| Chain | Residue | Details |
| Q | ASP6 | |
| Q | LYS83 | |
| Q | GLU57 |
| site_id | CSA18 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1onr |
| Chain | Residue | Details |
| R | ASP6 | |
| R | LYS83 | |
| R | GLU57 |
| site_id | CSA19 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1onr |
| Chain | Residue | Details |
| S | ASP6 | |
| S | LYS83 | |
| S | GLU57 |
| site_id | CSA2 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1onr |
| Chain | Residue | Details |
| B | ASP6 | |
| B | LYS83 | |
| B | GLU57 |
| site_id | CSA20 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1onr |
| Chain | Residue | Details |
| T | ASP6 | |
| T | LYS83 | |
| T | GLU57 |
| site_id | CSA3 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1onr |
| Chain | Residue | Details |
| C | ASP6 | |
| C | LYS83 | |
| C | GLU57 |
| site_id | CSA4 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1onr |
| Chain | Residue | Details |
| D | ASP6 | |
| D | LYS83 | |
| D | GLU57 |
| site_id | CSA5 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1onr |
| Chain | Residue | Details |
| E | ASP6 | |
| E | LYS83 | |
| E | GLU57 |
| site_id | CSA6 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1onr |
| Chain | Residue | Details |
| F | ASP6 | |
| F | LYS83 | |
| F | GLU57 |
| site_id | CSA7 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1onr |
| Chain | Residue | Details |
| G | ASP6 | |
| G | LYS83 | |
| G | GLU57 |
| site_id | CSA8 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1onr |
| Chain | Residue | Details |
| H | ASP6 | |
| H | LYS83 | |
| H | GLU57 |
| site_id | CSA9 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1onr |
| Chain | Residue | Details |
| I | ASP6 | |
| I | LYS83 | |
| I | GLU57 |
