Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

1VPX

Crystal structure of Transaldolase (EC 2.2.1.2) (TM0295) from Thermotoga maritima at 2.40 A resolution

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004801	molecular_function	transaldolase activity
A	0005737	cellular_component	cytoplasm
A	0005975	biological_process	carbohydrate metabolic process
A	0006098	biological_process	pentose-phosphate shunt
A	0016740	molecular_function	transferase activity
A	0016832	molecular_function	aldehyde-lyase activity
B	0004801	molecular_function	transaldolase activity
B	0005737	cellular_component	cytoplasm
B	0005975	biological_process	carbohydrate metabolic process
B	0006098	biological_process	pentose-phosphate shunt
B	0016740	molecular_function	transferase activity
B	0016832	molecular_function	aldehyde-lyase activity
C	0004801	molecular_function	transaldolase activity
C	0005737	cellular_component	cytoplasm
C	0005975	biological_process	carbohydrate metabolic process
C	0006098	biological_process	pentose-phosphate shunt
C	0016740	molecular_function	transferase activity
C	0016832	molecular_function	aldehyde-lyase activity
D	0004801	molecular_function	transaldolase activity
D	0005737	cellular_component	cytoplasm
D	0005975	biological_process	carbohydrate metabolic process
D	0006098	biological_process	pentose-phosphate shunt
D	0016740	molecular_function	transferase activity
D	0016832	molecular_function	aldehyde-lyase activity
E	0004801	molecular_function	transaldolase activity
E	0005737	cellular_component	cytoplasm
E	0005975	biological_process	carbohydrate metabolic process
E	0006098	biological_process	pentose-phosphate shunt
E	0016740	molecular_function	transferase activity
E	0016832	molecular_function	aldehyde-lyase activity
F	0004801	molecular_function	transaldolase activity
F	0005737	cellular_component	cytoplasm
F	0005975	biological_process	carbohydrate metabolic process
F	0006098	biological_process	pentose-phosphate shunt
F	0016740	molecular_function	transferase activity
F	0016832	molecular_function	aldehyde-lyase activity
G	0004801	molecular_function	transaldolase activity
G	0005737	cellular_component	cytoplasm
G	0005975	biological_process	carbohydrate metabolic process
G	0006098	biological_process	pentose-phosphate shunt
G	0016740	molecular_function	transferase activity
G	0016832	molecular_function	aldehyde-lyase activity
H	0004801	molecular_function	transaldolase activity
H	0005737	cellular_component	cytoplasm
H	0005975	biological_process	carbohydrate metabolic process
H	0006098	biological_process	pentose-phosphate shunt
H	0016740	molecular_function	transferase activity
H	0016832	molecular_function	aldehyde-lyase activity
I	0004801	molecular_function	transaldolase activity
I	0005737	cellular_component	cytoplasm
I	0005975	biological_process	carbohydrate metabolic process
I	0006098	biological_process	pentose-phosphate shunt
I	0016740	molecular_function	transferase activity
I	0016832	molecular_function	aldehyde-lyase activity
J	0004801	molecular_function	transaldolase activity
J	0005737	cellular_component	cytoplasm
J	0005975	biological_process	carbohydrate metabolic process
J	0006098	biological_process	pentose-phosphate shunt
J	0016740	molecular_function	transferase activity
J	0016832	molecular_function	aldehyde-lyase activity
K	0004801	molecular_function	transaldolase activity
K	0005737	cellular_component	cytoplasm
K	0005975	biological_process	carbohydrate metabolic process
K	0006098	biological_process	pentose-phosphate shunt
K	0016740	molecular_function	transferase activity
K	0016832	molecular_function	aldehyde-lyase activity
L	0004801	molecular_function	transaldolase activity
L	0005737	cellular_component	cytoplasm
L	0005975	biological_process	carbohydrate metabolic process
L	0006098	biological_process	pentose-phosphate shunt
L	0016740	molecular_function	transferase activity
L	0016832	molecular_function	aldehyde-lyase activity
M	0004801	molecular_function	transaldolase activity
M	0005737	cellular_component	cytoplasm
M	0005975	biological_process	carbohydrate metabolic process
M	0006098	biological_process	pentose-phosphate shunt
M	0016740	molecular_function	transferase activity
M	0016832	molecular_function	aldehyde-lyase activity
N	0004801	molecular_function	transaldolase activity
N	0005737	cellular_component	cytoplasm
N	0005975	biological_process	carbohydrate metabolic process
N	0006098	biological_process	pentose-phosphate shunt
N	0016740	molecular_function	transferase activity
N	0016832	molecular_function	aldehyde-lyase activity
O	0004801	molecular_function	transaldolase activity
O	0005737	cellular_component	cytoplasm
O	0005975	biological_process	carbohydrate metabolic process
O	0006098	biological_process	pentose-phosphate shunt
O	0016740	molecular_function	transferase activity
O	0016832	molecular_function	aldehyde-lyase activity
P	0004801	molecular_function	transaldolase activity
P	0005737	cellular_component	cytoplasm
P	0005975	biological_process	carbohydrate metabolic process
P	0006098	biological_process	pentose-phosphate shunt
P	0016740	molecular_function	transferase activity
P	0016832	molecular_function	aldehyde-lyase activity
Q	0004801	molecular_function	transaldolase activity
Q	0005737	cellular_component	cytoplasm
Q	0005975	biological_process	carbohydrate metabolic process
Q	0006098	biological_process	pentose-phosphate shunt
Q	0016740	molecular_function	transferase activity
Q	0016832	molecular_function	aldehyde-lyase activity
R	0004801	molecular_function	transaldolase activity
R	0005737	cellular_component	cytoplasm
R	0005975	biological_process	carbohydrate metabolic process
R	0006098	biological_process	pentose-phosphate shunt
R	0016740	molecular_function	transferase activity
R	0016832	molecular_function	aldehyde-lyase activity
S	0004801	molecular_function	transaldolase activity
S	0005737	cellular_component	cytoplasm
S	0005975	biological_process	carbohydrate metabolic process
S	0006098	biological_process	pentose-phosphate shunt
S	0016740	molecular_function	transferase activity
S	0016832	molecular_function	aldehyde-lyase activity
T	0004801	molecular_function	transaldolase activity
T	0005737	cellular_component	cytoplasm
T	0005975	biological_process	carbohydrate metabolic process
T	0006098	biological_process	pentose-phosphate shunt
T	0016740	molecular_function	transferase activity
T	0016832	molecular_function	aldehyde-lyase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 O 219

Chain	Residue
O	LYS2
O	ASP23
O	LYS51

site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL B 219

Chain	Residue
B	VAL148
B	TYR151
B	ASN152
B	PHE156
B	THR158
B	ASP180

site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL C 219

Chain	Residue
C	TYR151
C	ASN152
C	PHE156
C	THR158
C	ASP180

site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL R 219

Chain	Residue
R	TYR151
R	PHE156
R	GLU157
R	THR158
R	GLU159
R	ASP180

site_id	AC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL S 219

Chain	Residue
S	ASN152
S	PHE156
S	THR158
S	ASP180

site_id	AC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL K 219

Chain	Residue
K	TYR151
K	ASN152
K	GLY155
K	PHE156
K	THR158
K	ASP180

site_id	AC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL N 219

Chain	Residue
N	TYR151
N	PHE156
N	THR158
N	ASP180

site_id	AC8
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL O 220

Chain	Residue
O	TYR151
O	GLY155
O	PHE156
O	THR158
O	ASP180

site_id	AC9
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL F 219

Chain	Residue
F	TYR151
F	ASN152
F	PHE156
F	THR158
F	ASP180

site_id	BC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL G 219

Chain	Residue
G	VAL148
G	TYR151
G	ASN152
G	PHE156
G	THR158
G	ASP180

site_id	BC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL H 219

Chain	Residue
H	VAL148
H	TYR151
H	ASN152
H	PHE156
H	THR158
H	ILE160
H	ASP180

site_id	BC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL I 219

Chain	Residue
I	TYR151
I	ASN152
I	PHE156
I	THR158
I	ASP180

site_id	BC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL J 219

Chain	Residue
J	TYR151
J	ASN152
J	PHE156
J	THR158
J	ASP180

site_id	BC5
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL A 219

Chain	Residue
A	VAL148
A	TYR151
A	ASN152
A	PHE156
A	THR158
A	ASP180
A	HOH221

site_id	BC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL D 219

Chain	Residue
D	TYR151
D	ASN152
D	PHE156
D	THR158
D	ILE160
D	ASP180

site_id	BC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL E 219

Chain	Residue
E	TYR151
E	PHE156
E	THR158
E	ASP180

site_id	BC8
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL P 219

Chain	Residue
P	TYR151
P	ASN152
P	PHE156
P	GLU157
P	THR158
P	ASP180

site_id	BC9
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL Q 219

Chain	Residue
Q	TYR151
Q	ASN152
Q	PHE156
Q	THR158
Q	ASP180

site_id	CC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL T 219

Chain	Residue
T	ASP180
T	TYR151
T	GLY155
T	PHE156
T	THR158

site_id	CC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL L 219

Chain	Residue
L	TYR151
L	ASN152
L	PHE156
L	GLU157
L	THR158
L	GLU159
L	ASP180

site_id	CC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL M 219

Chain	Residue
M	TYR151
M	ASN152
M	PHE156
M	THR158
M	ASP180

site_id	CC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL P 220

Chain	Residue
P	ASP23
P	VAL50
P	LYS51
P	GLY52

Functional Information from PROSITE/UniProt

site_id	PS00958
Number of Residues	18
Details	TRANSALDOLASE_2 Transaldolase active site. VvIKIPmTpDGIkAvKtL

Chain	Residue	Details
A	VAL80-LEU97

site_id	PS01054
Number of Residues	9
Details	TRANSALDOLASE_1 Transaldolase signature 1. GVTTNPTLI

Chain	Residue	Details
A	GLY24-ILE32

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	20
Details	ACT_SITE: Schiff-base intermediate with substrate => ECO:0000250

Chain	Residue	Details
A	LYS83
B	LYS83
C	LYS83
D	LYS83
E	LYS83
F	LYS83
G	LYS83
H	LYS83
I	LYS83
J	LYS83
K	LYS83
L	LYS83
M	LYS83
N	LYS83
O	LYS83
P	LYS83
Q	LYS83
R	LYS83
S	LYS83
T	LYS83

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)