1VL0
CRYSTAL STRUCTURE OF A DTDP-4-DEHYDRORHAMNOSE REDUCTASE, RFBD ORTHOLOG (CA_C2315) FROM CLOSTRIDIUM ACETOBUTYLICUM ATCC 824 AT 2.05 A RESOLUTION
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0005829 | cellular_component | cytosol |
| A | 0008831 | molecular_function | dTDP-4-dehydrorhamnose reductase activity |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0019305 | biological_process | dTDP-rhamnose biosynthetic process |
| A | 0045226 | biological_process | extracellular polysaccharide biosynthetic process |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0005829 | cellular_component | cytosol |
| B | 0008831 | molecular_function | dTDP-4-dehydrorhamnose reductase activity |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0019305 | biological_process | dTDP-rhamnose biosynthetic process |
| B | 0045226 | biological_process | extracellular polysaccharide biosynthetic process |
| C | 0000166 | molecular_function | nucleotide binding |
| C | 0005829 | cellular_component | cytosol |
| C | 0008831 | molecular_function | dTDP-4-dehydrorhamnose reductase activity |
| C | 0016491 | molecular_function | oxidoreductase activity |
| C | 0019305 | biological_process | dTDP-rhamnose biosynthetic process |
| C | 0045226 | biological_process | extracellular polysaccharide biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE NAI A 300 |
| Chain | Residue |
| A | GLY10 |
| A | ALA60 |
| A | THR62 |
| A | ILE99 |
| A | SER100 |
| A | THR101 |
| A | TYR125 |
| A | LYS129 |
| A | THR148 |
| A | TRP150 |
| A | LEU151 |
| A | GLN11 |
| A | HOH313 |
| A | HOH383 |
| A | LEU12 |
| A | ASP31 |
| A | LEU35 |
| A | ASP36 |
| A | ILE37 |
| A | CYS58 |
| A | ALA59 |
| site_id | AC2 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE UNL A 301 |
| Chain | Residue |
| A | THR207 |
| A | CYS208 |
| A | GLY210 |
| A | ILE211 |
| A | LEU251 |
| A | ARG252 |
| A | ASN253 |
| A | HOH309 |
| A | HOH324 |
| A | HOH337 |
| site_id | AC3 |
| Number of Residues | 25 |
| Details | BINDING SITE FOR RESIDUE NAI B 300 |
| Chain | Residue |
| B | GLY10 |
| B | GLN11 |
| B | LEU12 |
| B | ASP31 |
| B | VAL32 |
| B | LEU35 |
| B | ASP36 |
| B | ILE37 |
| B | CYS58 |
| B | ALA59 |
| B | ALA60 |
| B | THR62 |
| B | ILE77 |
| B | ILE99 |
| B | SER100 |
| B | THR101 |
| B | TYR125 |
| B | LYS129 |
| B | THR148 |
| B | LEU151 |
| B | HOH306 |
| B | HOH309 |
| B | HOH349 |
| B | HOH360 |
| B | HOH445 |
| site_id | AC4 |
| Number of Residues | 24 |
| Details | BINDING SITE FOR RESIDUE NAI C 300 |
| Chain | Residue |
| C | GLY10 |
| C | GLN11 |
| C | LEU12 |
| C | ASP31 |
| C | VAL32 |
| C | LEU35 |
| C | ASP36 |
| C | ILE37 |
| C | CYS58 |
| C | ALA59 |
| C | ALA60 |
| C | THR62 |
| C | ILE99 |
| C | SER100 |
| C | THR101 |
| C | TYR125 |
| C | LYS129 |
| C | THR148 |
| C | TRP150 |
| C | LEU151 |
| C | HOH306 |
| C | HOH310 |
| C | HOH318 |
| C | HOH394 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1db3 |
| Chain | Residue | Details |
| A | TYR103 | |
| A | THR101 | |
| A | LYS129 | |
| A | TYR125 |
| site_id | CSA10 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1db3 |
| Chain | Residue | Details |
| A | GLN122 | |
| A | LYS129 |
| site_id | CSA11 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1db3 |
| Chain | Residue | Details |
| B | GLN122 | |
| B | LYS129 |
| site_id | CSA12 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1db3 |
| Chain | Residue | Details |
| C | GLN122 | |
| C | LYS129 |
| site_id | CSA13 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1db3 |
| Chain | Residue | Details |
| A | LYS129 | |
| A | TYR125 |
| site_id | CSA14 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1db3 |
| Chain | Residue | Details |
| B | LYS129 | |
| B | TYR125 |
| site_id | CSA15 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1db3 |
| Chain | Residue | Details |
| C | LYS129 | |
| C | TYR125 |
| site_id | CSA2 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1db3 |
| Chain | Residue | Details |
| B | TYR103 | |
| B | THR101 | |
| B | LYS129 | |
| B | TYR125 |
| site_id | CSA3 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1db3 |
| Chain | Residue | Details |
| C | TYR103 | |
| C | THR101 | |
| C | LYS129 | |
| C | TYR125 |
| site_id | CSA4 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1db3 |
| Chain | Residue | Details |
| A | LYS129 | |
| A | THR101 | |
| A | TYR125 |
| site_id | CSA5 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1db3 |
| Chain | Residue | Details |
| B | LYS129 | |
| B | THR101 | |
| B | TYR125 |
| site_id | CSA6 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1db3 |
| Chain | Residue | Details |
| C | LYS129 | |
| C | THR101 | |
| C | TYR125 |
| site_id | CSA7 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1db3 |
| Chain | Residue | Details |
| A | LYS129 | |
| A | THR101 | |
| A | TYR125 | |
| A | ASN78 |
| site_id | CSA8 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1db3 |
| Chain | Residue | Details |
| B | LYS129 | |
| B | THR101 | |
| B | TYR125 | |
| B | ASN78 |
| site_id | CSA9 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1db3 |
| Chain | Residue | Details |
| C | LYS129 | |
| C | THR101 | |
| C | TYR125 | |
| C | ASN78 |
