1VIO
Crystal structure of pseudouridylate synthase
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000455 | biological_process | enzyme-directed rRNA pseudouridine synthesis |
| A | 0001522 | biological_process | pseudouridine synthesis |
| A | 0003723 | molecular_function | RNA binding |
| A | 0005829 | cellular_component | cytosol |
| A | 0006364 | biological_process | rRNA processing |
| A | 0009451 | biological_process | RNA modification |
| A | 0009982 | molecular_function | pseudouridine synthase activity |
| A | 0016853 | molecular_function | isomerase activity |
| A | 0016866 | molecular_function | intramolecular transferase activity |
| A | 0120159 | molecular_function | rRNA pseudouridine synthase activity |
| A | 0160136 | molecular_function | 16S rRNA pseudouridine(516) synthase activity |
| B | 0000455 | biological_process | enzyme-directed rRNA pseudouridine synthesis |
| B | 0001522 | biological_process | pseudouridine synthesis |
| B | 0003723 | molecular_function | RNA binding |
| B | 0005829 | cellular_component | cytosol |
| B | 0006364 | biological_process | rRNA processing |
| B | 0009451 | biological_process | RNA modification |
| B | 0009982 | molecular_function | pseudouridine synthase activity |
| B | 0016853 | molecular_function | isomerase activity |
| B | 0016866 | molecular_function | intramolecular transferase activity |
| B | 0120159 | molecular_function | rRNA pseudouridine synthase activity |
| B | 0160136 | molecular_function | 16S rRNA pseudouridine(516) synthase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE BU1 A 242 |
| Chain | Residue |
| A | GLU59 |
| A | GLN61 |
| A | LEU91 |
| A | HOH340 |
| A | HOH455 |
| A | HOH472 |
| B | ARG220 |
| B | HOH287 |
| B | HOH331 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE BU1 A 243 |
| Chain | Residue |
| A | ASP102 |
| A | THR105 |
| A | TYR132 |
| A | GLN185 |
| A | VAL186 |
| A | HOH255 |
| A | HOH359 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE BU1 A 244 |
| Chain | Residue |
| A | ASP104 |
| A | THR105 |
| A | LYS187 |
| A | LEU200 |
| A | HOH394 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE BU1 A 245 |
| Chain | Residue |
| A | ASN175 |
| A | HIS201 |
| A | HOH262 |
| A | HOH521 |
Functional Information from PROSITE/UniProt
| site_id | PS01149 |
| Number of Residues | 15 |
| Details | PSI_RSU Rsu family of pseudouridine synthase signature. GRLDvdTtGLVLLTD |
| Chain | Residue | Details |
| A | GLY99-ASP113 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: Nucleophile => ECO:0000250 |
| Chain | Residue | Details |
| A | ASP102 | |
| B | ASP102 |
