1V0D

Crystal Structure of Caspase-activated DNase (CAD)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000785	cellular_component	chromatin
A	0003677	molecular_function	DNA binding
A	0004518	molecular_function	nuclease activity
A	0004520	molecular_function	DNA endonuclease activity
A	0004536	molecular_function	DNA nuclease activity
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005654	cellular_component	nucleoplasm
A	0005730	cellular_component	nucleolus
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006308	biological_process	DNA catabolic process
A	0006309	biological_process	apoptotic DNA fragmentation
A	0006915	biological_process	apoptotic process
A	0016787	molecular_function	hydrolase activity
A	0019899	molecular_function	enzyme binding
A	0019904	molecular_function	protein domain specific binding
A	0030263	biological_process	apoptotic chromosome condensation
A	0032991	cellular_component	protein-containing complex
A	0042802	molecular_function	identical protein binding
A	0097718	molecular_function	disordered domain specific binding
A	1902511	biological_process	negative regulation of apoptotic DNA fragmentation

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 401

Chain	Residue
A	CYS229
A	CYS238
A	HIS242
A	CYS307

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site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG A 501

Chain	Residue
A	ASP262
A	HIS308
A	HOH2010
A	HOH2013

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site_id	AC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE PB A 601

Chain	Residue
A	CYS197

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