1UVN

The structural basis for RNA specificity and Ca2 inhibition of an RNA-dependent RNA polymerase phi6p2 ca2+ inhibition complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0001172	biological_process	RNA-templated transcription
A	0003723	molecular_function	RNA binding
A	0003968	molecular_function	RNA-directed RNA polymerase activity
A	0006351	biological_process	DNA-templated transcription
A	0016740	molecular_function	transferase activity
A	0016779	molecular_function	nucleotidyltransferase activity
A	0019079	biological_process	viral genome replication
A	0034062	molecular_function	5'-3' RNA polymerase activity
A	0039694	biological_process	viral RNA genome replication
A	0044423	cellular_component	virion component
A	0046872	molecular_function	metal ion binding
A	0050265	molecular_function	RNA uridylyltransferase activity
C	0000166	molecular_function	nucleotide binding
C	0001172	biological_process	RNA-templated transcription
C	0003723	molecular_function	RNA binding
C	0003968	molecular_function	RNA-directed RNA polymerase activity
C	0006351	biological_process	DNA-templated transcription
C	0016740	molecular_function	transferase activity
C	0016779	molecular_function	nucleotidyltransferase activity
C	0019079	biological_process	viral genome replication
C	0034062	molecular_function	5'-3' RNA polymerase activity
C	0039694	biological_process	viral RNA genome replication
C	0044423	cellular_component	virion component
C	0046872	molecular_function	metal ion binding
C	0050265	molecular_function	RNA uridylyltransferase activity
E	0000166	molecular_function	nucleotide binding
E	0001172	biological_process	RNA-templated transcription
E	0003723	molecular_function	RNA binding
E	0003968	molecular_function	RNA-directed RNA polymerase activity
E	0006351	biological_process	DNA-templated transcription
E	0016740	molecular_function	transferase activity
E	0016779	molecular_function	nucleotidyltransferase activity
E	0019079	biological_process	viral genome replication
E	0034062	molecular_function	5'-3' RNA polymerase activity
E	0039694	biological_process	viral RNA genome replication
E	0044423	cellular_component	virion component
E	0046872	molecular_function	metal ion binding
E	0050265	molecular_function	RNA uridylyltransferase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CA A1667

Chain	Residue
A	ARG204
A	TYR630
A	GTP1665

---

site_id	AC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CA A1668

Chain	Residue
A	VAL325
A	ASP453
A	GTP1666

---

site_id	AC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MN A1669

Chain	Residue
A	ASP454
A	GLU491
A	ALA495

---

site_id	AC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CA C1667

Chain	Residue
C	ARG204
C	TYR630
C	GTP1665

---

site_id	AC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CA C1668

Chain	Residue
C	VAL325
C	ASP453
C	GTP1666

---

site_id	AC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MN C1669

Chain	Residue
C	ASP454
C	GLU491
C	ALA495

---

site_id	AC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CA E1667

Chain	Residue
E	ARG204
E	TYR630
E	GTP1665

---

site_id	AC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CA E1668

Chain	Residue
E	VAL325
E	ASP453
E	GTP1666

---

site_id	AC9
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MN E1669

Chain	Residue
E	ASP454
E	GLU491
E	ALA495

---

site_id	BC1
Number of Residues	10
Details	BINDING SITE FOR RESIDUE GTP A1665

Chain	Residue
A	SER452
A	ASP454
A	SER520
A	ASN626
A	GLN629
A	TYR630
A	LYS631
A	GTP1666
A	CA1667
B	C7

---

site_id	BC2
Number of Residues	15
Details	BINDING SITE FOR RESIDUE GTP A1666

Chain	Residue
A	ARG204
A	ARG268
A	ARG270
A	SER326
A	ASP327
A	HIS328
A	ASP329
A	SER393
A	SER452
A	ASP453
A	GTP1665
A	CA1668
A	HOH2023
B	C6
B	C7

---

site_id	BC3
Number of Residues	10
Details	BINDING SITE FOR RESIDUE GTP C1665

Chain	Residue
C	SER452
C	ASP454
C	SER520
C	ASN626
C	GLN629
C	TYR630
C	LYS631
C	GTP1666
C	CA1667
D	C7

---

site_id	BC4
Number of Residues	15
Details	BINDING SITE FOR RESIDUE GTP C1666

Chain	Residue
C	ARG204
C	ARG268
C	ARG270
C	SER326
C	ASP327
C	HIS328
C	ASP329
C	SER393
C	SER452
C	ASP453
C	GTP1665
C	CA1668
C	HOH2023
D	C6
D	C7

---

site_id	BC5
Number of Residues	10
Details	BINDING SITE FOR RESIDUE GTP E1665

Chain	Residue
E	SER452
E	ASP454
E	SER520
E	ASN626
E	GLN629
E	TYR630
E	LYS631
E	GTP1666
E	CA1667
F	C7

---

site_id	BC6
Number of Residues	15
Details	BINDING SITE FOR RESIDUE GTP E1666

Chain	Residue
E	HOH2023
F	C6
F	C7
E	ARG204
E	ARG268
E	ARG270
E	SER326
E	ASP327
E	HIS328
E	ASP329
E	SER393
E	SER452
E	ASP453
E	GTP1665
E	CA1668

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	525
Details	Domain: {"description":"RdRp catalytic","evidences":[{"source":"PROSITE-ProRule","id":"PRU00539","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	9
Details	Binding site: {}

Chain

Residue

Details

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