1USY
ATP phosphoribosyl transferase (HisG:HisZ) complex from Thermotoga maritima
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000105 | biological_process | L-histidine biosynthetic process |
| A | 0004821 | molecular_function | histidine-tRNA ligase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006427 | biological_process | histidyl-tRNA aminoacylation |
| B | 0000105 | biological_process | L-histidine biosynthetic process |
| B | 0004821 | molecular_function | histidine-tRNA ligase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0006427 | biological_process | histidyl-tRNA aminoacylation |
| C | 0000105 | biological_process | L-histidine biosynthetic process |
| C | 0004821 | molecular_function | histidine-tRNA ligase activity |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0005829 | cellular_component | cytosol |
| C | 0006427 | biological_process | histidyl-tRNA aminoacylation |
| D | 0000105 | biological_process | L-histidine biosynthetic process |
| D | 0004821 | molecular_function | histidine-tRNA ligase activity |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0005829 | cellular_component | cytosol |
| D | 0006427 | biological_process | histidyl-tRNA aminoacylation |
| E | 0000105 | biological_process | L-histidine biosynthetic process |
| E | 0003879 | molecular_function | ATP phosphoribosyltransferase activity |
| E | 0005737 | cellular_component | cytoplasm |
| F | 0000105 | biological_process | L-histidine biosynthetic process |
| F | 0003879 | molecular_function | ATP phosphoribosyltransferase activity |
| F | 0005737 | cellular_component | cytoplasm |
| G | 0000105 | biological_process | L-histidine biosynthetic process |
| G | 0003879 | molecular_function | ATP phosphoribosyltransferase activity |
| G | 0005737 | cellular_component | cytoplasm |
| H | 0000105 | biological_process | L-histidine biosynthetic process |
| H | 0003879 | molecular_function | ATP phosphoribosyltransferase activity |
| H | 0005737 | cellular_component | cytoplasm |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PO4 E 1202 |
| Chain | Residue |
| E | THR149 |
| E | GLU150 |
| E | THR151 |
| E | GLY152 |
| E | ARG153 |
| E | THR154 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PO4 E 1203 |
| Chain | Residue |
| F | LYS8 |
| E | LYS108 |
| E | GLY131 |
| E | SER132 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PO4 F 1203 |
| Chain | Residue |
| F | GLU150 |
| F | THR151 |
| F | GLY152 |
| F | ARG153 |
| F | THR154 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PO4 G 1204 |
| Chain | Residue |
| G | GLU150 |
| G | THR151 |
| G | GLY152 |
| G | ARG153 |
| G | THR154 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PO4 G 1205 |
| Chain | Residue |
| G | LYS108 |
| G | GLY131 |
| G | SER132 |
| G | HOH2024 |
| H | ARG45 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PO4 H 1202 |
| Chain | Residue |
| H | THR149 |
| H | GLU150 |
| H | THR151 |
| H | GLY152 |
| H | ARG153 |
| H | THR154 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE HIS C 1275 |
| Chain | Residue |
| C | LYS157 |
| C | LEU159 |
| C | ILE184 |
| C | TYR185 |
| G | PRO78 |
| G | TYR180 |
| G | GLN195 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE HIS D 1276 |
| Chain | Residue |
| D | TYR185 |
| F | LEU191 |
| F | GLN195 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE HIS E 1204 |
| Chain | Residue |
| B | LYS157 |
| B | ILE184 |
| E | PRO78 |
| E | TYR180 |
| E | HOH2020 |
| site_id | BC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE HIS E 1205 |
| Chain | Residue |
| B | GLU161 |
| E | THR65 |
| E | ARG170 |
| E | HIS172 |
| site_id | BC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE HIS F 1204 |
| Chain | Residue |
| D | GLU161 |
| F | THR65 |
| F | LEU68 |
| F | GLN77 |
| F | ARG170 |
| F | HIS172 |
| site_id | BC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE HIS G 1206 |
| Chain | Residue |
| C | ASN158 |
| G | THR65 |
| G | GLN77 |
| G | ARG170 |
| G | HIS172 |
| G | HOH2025 |
| G | HOH2026 |
| G | HOH2027 |
| site_id | BC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE HIS H 1203 |
| Chain | Residue |
| A | ILE184 |
| A | TYR185 |
| H | ILE76 |
| H | PRO78 |
| H | TYR180 |
| H | LEU191 |
| H | GLN195 |
| site_id | BC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE HIS H 1204 |
| Chain | Residue |
| A | GLU161 |
| A | HOH2023 |
| H | THR65 |
| H | GLN77 |
| H | ARG170 |
| H | HIS172 |
Functional Information from PROSITE/UniProt
| site_id | PS01316 |
| Number of Residues | 22 |
| Details | ATP_P_PHORIBOSYLTR ATP phosphoribosyltransferase signature. ElapiaGlSdlIvDIteTGrTL |
| Chain | Residue | Details |
| E | GLU134-LEU155 | |
| H | GLU134-LEU155 |
