1USL

Structure Of Mycobacterium tuberculosis Ribose-5-Phosphate Isomerase, RpiB, Rv2465c, Complexed With Phosphate.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004751	molecular_function	ribose-5-phosphate isomerase activity
A	0005515	molecular_function	protein binding
A	0005576	cellular_component	extracellular region
A	0005975	biological_process	carbohydrate metabolic process
A	0006098	biological_process	pentose-phosphate shunt
A	0009052	biological_process	pentose-phosphate shunt, non-oxidative branch
A	0016853	molecular_function	isomerase activity
A	0016861	molecular_function	intramolecular oxidoreductase activity, interconverting aldoses and ketoses
A	0019316	biological_process	D-allose catabolic process
B	0004751	molecular_function	ribose-5-phosphate isomerase activity
B	0005515	molecular_function	protein binding
B	0005576	cellular_component	extracellular region
B	0005975	biological_process	carbohydrate metabolic process
B	0006098	biological_process	pentose-phosphate shunt
B	0009052	biological_process	pentose-phosphate shunt, non-oxidative branch
B	0016853	molecular_function	isomerase activity
B	0016861	molecular_function	intramolecular oxidoreductase activity, interconverting aldoses and ketoses
B	0019316	biological_process	D-allose catabolic process
C	0004751	molecular_function	ribose-5-phosphate isomerase activity
C	0005515	molecular_function	protein binding
C	0005576	cellular_component	extracellular region
C	0005975	biological_process	carbohydrate metabolic process
C	0006098	biological_process	pentose-phosphate shunt
C	0009052	biological_process	pentose-phosphate shunt, non-oxidative branch
C	0016853	molecular_function	isomerase activity
C	0016861	molecular_function	intramolecular oxidoreductase activity, interconverting aldoses and ketoses
C	0019316	biological_process	D-allose catabolic process
D	0004751	molecular_function	ribose-5-phosphate isomerase activity
D	0005515	molecular_function	protein binding
D	0005576	cellular_component	extracellular region
D	0005975	biological_process	carbohydrate metabolic process
D	0006098	biological_process	pentose-phosphate shunt
D	0009052	biological_process	pentose-phosphate shunt, non-oxidative branch
D	0016853	molecular_function	isomerase activity
D	0016861	molecular_function	intramolecular oxidoreductase activity, interconverting aldoses and ketoses
D	0019316	biological_process	D-allose catabolic process
E	0004751	molecular_function	ribose-5-phosphate isomerase activity
E	0005515	molecular_function	protein binding
E	0005576	cellular_component	extracellular region
E	0005975	biological_process	carbohydrate metabolic process
E	0006098	biological_process	pentose-phosphate shunt
E	0009052	biological_process	pentose-phosphate shunt, non-oxidative branch
E	0016853	molecular_function	isomerase activity
E	0016861	molecular_function	intramolecular oxidoreductase activity, interconverting aldoses and ketoses
E	0019316	biological_process	D-allose catabolic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE PO4 A1159

Chain	Residue
A	ARG137
A	ARG141
A	HOH2110
A	HOH2111
A	HOH2112
B	HIS12
B	ARG113

---

site_id	AC2
Number of Residues	9
Details	BINDING SITE FOR RESIDUE PO4 B1159

Chain	Residue
A	HOH2007
B	ARG137
B	HIS138
B	ARG141
B	HOH2114
B	HOH2115
B	HOH2116
A	HIS12
A	ALA13

---

site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE PO4 C1161

Chain	Residue
C	ARG137
C	ARG141
C	HOH2110
C	HOH2111
D	HIS12
D	HOH2005

---

site_id	AC4
Number of Residues	8
Details	BINDING SITE FOR RESIDUE PO4 D1159

Chain	Residue
C	HIS12
C	HOH2004
D	ARG137
D	HIS138
D	ARG141
D	HOH2137
D	HOH2138
D	HOH2139

---

site_id	AC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE PO4 E1159

Chain	Residue
E	HIS12
E	ARG137
E	HIS138
E	ARG141
E	HOH2100
E	HOH2101

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	5
Details	ACT_SITE: Proton acceptor => ECO:0000305|PubMed:15590681, ECO:0000305|PubMed:18640127, ECO:0007744|PDB:2BES, ECO:0007744|PDB:2BET, ECO:0007744|PDB:2VVO, ECO:0007744|PDB:2VVP, ECO:0007744|PDB:2VVQ

Chain	Residue	Details
A	GLU75
B	GLU75
C	GLU75
D	GLU75
E	GLU75

---

site_id	SWS_FT_FI2
Number of Residues	5
Details	ACT_SITE: Proton donor => ECO:0000305|PubMed:15590681, ECO:0000305|PubMed:18640127, ECO:0007744|PDB:2BES, ECO:0007744|PDB:2BET, ECO:0007744|PDB:2VVO, ECO:0007744|PDB:2VVP, ECO:0007744|PDB:2VVQ

Chain	Residue	Details
A	HIS102
B	HIS102
C	HIS102
D	HIS102
E	HIS102

---

site_id	SWS_FT_FI3
Number of Residues	15
Details	BINDING: BINDING => ECO:0000269|PubMed:14687575, ECO:0000269|PubMed:15590681, ECO:0000269|PubMed:18640127, ECO:0007744|PDB:1USL, ECO:0007744|PDB:2BES, ECO:0007744|PDB:2BET, ECO:0007744|PDB:2VVO, ECO:0007744|PDB:2VVP, ECO:0007744|PDB:2VVQ

Chain	Residue	Details
A	ASP11
D	ASP11
D	ARG113
D	ARG137
E	ASP11
E	ARG113
E	ARG137
A	ARG113
A	ARG137
B	ASP11
B	ARG113
B	ARG137
C	ASP11
C	ARG113
C	ARG137

---

site_id	SWS_FT_FI4
Number of Residues	5
Details	BINDING: BINDING => ECO:0000269|PubMed:15590681, ECO:0000269|PubMed:18640127, ECO:0007744|PDB:2BES, ECO:0007744|PDB:2BET, ECO:0007744|PDB:2VVO, ECO:0007744|PDB:2VVP, ECO:0007744|PDB:2VVQ

Chain	Residue	Details
A	GLY70
B	GLY70
C	GLY70
D	GLY70
E	GLY70

---

site_id	SWS_FT_FI5
Number of Residues	5
Details	BINDING: BINDING => ECO:0000269|PubMed:15590681, ECO:0000269|PubMed:18640127, ECO:0007744|PDB:2BET, ECO:0007744|PDB:2VVO, ECO:0007744|PDB:2VVP

Chain	Residue	Details
A	ASN103
B	ASN103
C	ASN103
D	ASN103
E	ASN103

---

site_id	SWS_FT_FI6
Number of Residues	5
Details	BINDING: BINDING => ECO:0000269|PubMed:14687575, ECO:0000269|PubMed:18640127, ECO:0007744|PDB:1USL, ECO:0007744|PDB:2VVO, ECO:0007744|PDB:2VVP, ECO:0007744|PDB:2VVQ

Chain	Residue	Details
A	ARG141
B	ARG141
C	ARG141
D	ARG141
E	ARG141

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