1URQ
Crystal structure of neuronal Q-SNAREs in complex with R-SNARE motif of Tomosyn
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| B | 0005484 | molecular_function | SNAP receptor activity |
| B | 0006886 | biological_process | intracellular protein transport |
| B | 0016020 | cellular_component | membrane |
| B | 0016192 | biological_process | vesicle-mediated transport |
| C | 0000149 | molecular_function | SNARE binding |
| C | 0005249 | molecular_function | voltage-gated potassium channel activity |
| C | 0017075 | molecular_function | syntaxin-1 binding |
Functional Information from PROSITE/UniProt
| site_id | PS00914 |
| Number of Residues | 40 |
| Details | SYNTAXIN Syntaxin / epimorphin family signature. RhseIikLEnsIrELhdMFmdMamlVesQGemIDrIEyn.V |
| Chain | Residue | Details |
| B | ARG198-VAL237 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | SITE: (Microbial infection) Cleavage; by C.botulinum neurotoxin type E (BoNT/E) => ECO:0000269|PubMed:8243676, ECO:0000269|PubMed:8294407, ECO:0000305|PubMed:8103915 |
| Chain | Residue | Details |
| D | ARG179 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | SITE: (Microbial infection) Cleavage; by C.botulinum neurotoxin type A (BoNT/A, botA) => ECO:0000269|PubMed:8243676, ECO:0000269|PubMed:8294407, ECO:0000305|PubMed:8103915 |
| Chain | Residue | Details |
| D | GLN196 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphothreonine; by PKC and PKA => ECO:0000269|PubMed:12459461 |
| Chain | Residue | Details |
| D | LYS200 | |
| B | LYS253 | |
| B | LYS256 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P60879 |
| Chain | Residue | Details |
| D | SER153 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine; by PKC => ECO:0000269|PubMed:12459461 |
| Chain | Residue | Details |
| D | SER186 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 4 |
| Details | LIPID: S-palmitoyl cysteine => ECO:0000250|UniProtKB:P60879 |
| Chain | Residue | Details |
| D | GLU147 | |
| D | GLU150 | |
| D | VAL152 | |
| D | GLY154 |
