1UQU
Trehalose-6-phosphate from E. coli bound with UDP-glucose.
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0003825 | molecular_function | alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity |
| A | 0005992 | biological_process | trehalose biosynthetic process |
| A | 0006950 | biological_process | response to stress |
| A | 0006970 | biological_process | response to osmotic stress |
| A | 0006974 | biological_process | DNA damage response |
| A | 0016758 | molecular_function | hexosyltransferase activity |
| A | 0070417 | biological_process | cellular response to cold |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0003825 | molecular_function | alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity |
| B | 0005992 | biological_process | trehalose biosynthetic process |
| B | 0006950 | biological_process | response to stress |
| B | 0006970 | biological_process | response to osmotic stress |
| B | 0006974 | biological_process | DNA damage response |
| B | 0016758 | molecular_function | hexosyltransferase activity |
| B | 0070417 | biological_process | cellular response to cold |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 24 |
| Details | BINDING SITE FOR RESIDUE UPG A1457 |
| Chain | Residue |
| A | TRP85 |
| A | PHE339 |
| A | ARG341 |
| A | LEU344 |
| A | ASP361 |
| A | GLY362 |
| A | MET363 |
| A | ASN364 |
| A | LEU365 |
| A | VAL366 |
| A | GLU369 |
| A | HIS154 |
| A | HOH2052 |
| A | HOH2069 |
| A | HOH2070 |
| A | HOH2072 |
| A | HOH2073 |
| A | GLN185 |
| A | ILE225 |
| A | VAL260 |
| A | ARG262 |
| A | LYS267 |
| A | PRO297 |
| A | HIS338 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"12498887","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"20077550","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1GZ5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2WTX","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"12498887","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"14570926","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"20077550","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"1GZ5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2WTX","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 14 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"12498887","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"14570926","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"20077550","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"1GZ5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1UQT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1UQU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2WTX","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | Site: {"description":"Involved in alpha anomer selectivity","evidences":[{"source":"PubMed","id":"12498887","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1uqt |
| Chain | Residue | Details |
| A | ASP361 | |
| A | HIS154 |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1uqt |
| Chain | Residue | Details |
| B | ASP361 | |
| B | HIS154 |
| site_id | MCSA1 |
| Number of Residues | 2 |
| Details | M-CSA 622 |
| Chain | Residue | Details |
| A | HIS154 | electrostatic stabiliser |
| A | ASP361 | electrostatic stabiliser |
| site_id | MCSA2 |
| Number of Residues | 2 |
| Details | M-CSA 622 |
| Chain | Residue | Details |
| B | HIS154 | electrostatic stabiliser |
| B | ASP361 | electrostatic stabiliser |
