1UPI
Mycobacterium tuberculosis rmlC epimerase (Rv3465)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005515 | molecular_function | protein binding |
| A | 0005829 | cellular_component | cytosol |
| A | 0008830 | molecular_function | dTDP-4-dehydrorhamnose 3,5-epimerase activity |
| A | 0016853 | molecular_function | isomerase activity |
| A | 0019305 | biological_process | dTDP-rhamnose biosynthetic process |
| A | 0045226 | biological_process | extracellular polysaccharide biosynthetic process |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | ACT_SITE: Proton acceptor => ECO:0000305|PubMed:17046787, ECO:0007744|PDB:2IXC |
| Chain | Residue | Details |
| A | HIS62 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | ACT_SITE: Proton donor => ECO:0000250|UniProtKB:Q9HU21 |
| Chain | Residue | Details |
| A | TYR132 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:17046787, ECO:0007744|PDB:2IXC |
| Chain | Residue | Details |
| A | ARG23 | |
| A | GLU28 | |
| A | ARG59 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000305|PubMed:17046787, ECO:0007744|PDB:2IXC |
| Chain | Residue | Details |
| A | GLN47 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:17046787, ECO:0000305|PubMed:12951098, ECO:0007744|PDB:1PM7 |
| Chain | Residue | Details |
| A | LYS72 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:17046787, ECO:0000305|PubMed:12951098, ECO:0007744|PDB:1PM7, ECO:0007744|PDB:2IXC |
| Chain | Residue | Details |
| A | HIS119 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000250|UniProtKB:Q9HU21 |
| Chain | Residue | Details |
| A | GLU143 | |
| A | ARG170 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 1 |
| Details | SITE: Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose => ECO:0000250|UniProtKB:Q5SFD1 |
| Chain | Residue | Details |
| A | TYR138 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1dzr |
| Chain | Residue | Details |
| A | HIS62 | |
| A | ASP171 |
