1UNQ

High resolution crystal structure of the Pleckstrin Homology Domain Of Protein Kinase B/Akt Bound To Ins(1,3,4,5)-Tetrakisphophate

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004674	molecular_function	protein serine/threonine kinase activity
A	0043491	biological_process	protein kinase B signaling

Functional Information from PDB Data

site_id	AC1
Number of Residues	28
Details	BINDING SITE FOR RESIDUE 4IP A1117

Chain	Residue
A	ACE-1
A	ILE19
A	ARG23
A	ARG25
A	LEU52
A	ASN53
A	PHE55
A	ARG86
A	HOH2007
A	HOH2105
A	HOH2146
A	SER0
A	HOH2147
A	HOH2148
A	HOH2149
A	HOH2150
A	HOH2151
A	HOH2152
A	HOH2153
A	HOH2154
A	HOH2155
A	MET1
A	SER2
A	HIS13
A	LYS14
A	GLY16
A	GLU17
A	TYR18

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	BINDING: BINDING => ECO:0000269|PubMed:12176338, ECO:0000269|PubMed:12964941

Chain	Residue	Details
A	LYS14
A	ARG23
A	ASN53
A	ARG86

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site_id	SWS_FT_FI2
Number of Residues	2
Details	MOD_RES: N6-acetyllysine => ECO:0000269|PubMed:21775285

Chain	Residue	Details
A	LYS14
A	LYS20

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