Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

1U8R

Crystal Structure of an IdeR-DNA Complex Reveals a Conformational Change in Activated IdeR for Base-specific Interactions

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0003700	molecular_function	DNA-binding transcription factor activity
A	0006355	biological_process	regulation of DNA-templated transcription
A	0046914	molecular_function	transition metal ion binding
A	0046983	molecular_function	protein dimerization activity
B	0003677	molecular_function	DNA binding
B	0003700	molecular_function	DNA-binding transcription factor activity
B	0006355	biological_process	regulation of DNA-templated transcription
B	0046914	molecular_function	transition metal ion binding
B	0046983	molecular_function	protein dimerization activity
C	0003677	molecular_function	DNA binding
C	0003700	molecular_function	DNA-binding transcription factor activity
C	0006355	biological_process	regulation of DNA-templated transcription
C	0046914	molecular_function	transition metal ion binding
C	0046983	molecular_function	protein dimerization activity
D	0003677	molecular_function	DNA binding
D	0003700	molecular_function	DNA-binding transcription factor activity
D	0006355	biological_process	regulation of DNA-templated transcription
D	0046914	molecular_function	transition metal ion binding
D	0046983	molecular_function	protein dimerization activity
G	0003677	molecular_function	DNA binding
G	0003700	molecular_function	DNA-binding transcription factor activity
G	0006355	biological_process	regulation of DNA-templated transcription
G	0046914	molecular_function	transition metal ion binding
G	0046983	molecular_function	protein dimerization activity
H	0003677	molecular_function	DNA binding
H	0003700	molecular_function	DNA-binding transcription factor activity
H	0006355	biological_process	regulation of DNA-templated transcription
H	0046914	molecular_function	transition metal ion binding
H	0046983	molecular_function	protein dimerization activity
I	0003677	molecular_function	DNA binding
I	0003700	molecular_function	DNA-binding transcription factor activity
I	0006355	biological_process	regulation of DNA-templated transcription
I	0046914	molecular_function	transition metal ion binding
I	0046983	molecular_function	protein dimerization activity
J	0003677	molecular_function	DNA binding
J	0003700	molecular_function	DNA-binding transcription factor activity
J	0006355	biological_process	regulation of DNA-templated transcription
J	0046914	molecular_function	transition metal ion binding
J	0046983	molecular_function	protein dimerization activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CO A 1001

Chain	Residue
A	HIS79
A	GLU83
A	HIS98
A	GLU172
A	GLN175

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CO A 1002

Chain	Residue
A	MET10
A	CYS102
A	GLU105
A	HIS106

site_id	AC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CO A 1003

Chain	Residue
A	HIS219
A	HIS223

site_id	AC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CO B 2001

Chain	Residue
B	HIS79
B	GLU83
B	HIS98
B	GLU172
B	GLN175

site_id	AC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CO B 2002

Chain	Residue
B	MET10
B	CYS102
B	GLU105
B	HIS106

site_id	AC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CO B 2003

Chain	Residue
B	HIS219
B	HIS223
B	HOH2105

site_id	AC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CO C 3001

Chain	Residue
C	HIS79
C	GLU83
C	HIS98
C	GLU172
C	GLN175

site_id	AC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CO C 3002

Chain	Residue
C	MET10
C	CYS102
C	GLU105
C	HIS106

site_id	AC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CO C 3003

Chain	Residue
C	HIS219
C	HIS223
C	HOH3107
C	HOH3109

site_id	BC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CO D 4001

Chain	Residue
D	HIS79
D	GLU83
D	HIS98
D	GLU172
D	GLN175

site_id	BC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CO D 4002

Chain	Residue
D	MET10
D	CYS102
D	GLU105
D	HIS106

site_id	BC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CO D 4003

Chain	Residue
D	HIS219
D	HIS223
D	HOH4107

site_id	BC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CO G 5001

Chain	Residue
G	HIS79
G	GLU83
G	HIS98
G	GLU172
G	GLN175

site_id	BC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CO G 5002

Chain	Residue
G	MET10
G	CYS102
G	GLU105
G	HIS106

site_id	BC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CO G 5003

Chain	Residue
G	HIS219
G	HIS223
G	HOH5107

site_id	BC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CO H 6001

Chain	Residue
H	HIS79
H	GLU83
H	HIS98
H	GLU172
H	GLN175

site_id	BC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CO H 6002

Chain	Residue
H	MET10
H	CYS102
H	GLU105
H	HIS106

site_id	BC9
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CO H 6003

Chain	Residue
H	HIS219
H	HIS223
H	HOH6108

site_id	CC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CO I 7001

Chain	Residue
I	HIS79
I	GLU83
I	HIS98
I	GLU172
I	GLN175

site_id	CC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CO I 7002

Chain	Residue
I	MET10
I	CYS102
I	GLU105
I	HIS106

site_id	CC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CO I 7003

Chain	Residue
I	HIS219
I	HIS223
I	HOH7111

site_id	CC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CO J 8001

Chain	Residue
J	HIS79
J	GLU83
J	HIS98
J	GLU172
J	GLN175

site_id	CC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CO J 8002

Chain	Residue
J	MET10
J	CYS102
J	GLU105
J	HIS106

site_id	CC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CO J 8003

Chain	Residue
J	HIS219
J	HIS223
J	HOH8109

site_id	CC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE NA A 1101

Chain	Residue
F	HOH37
A	ASP35
A	HOH1103
F	DC19

site_id	CC8
Number of Residues	2
Details	BINDING SITE FOR RESIDUE NA B 2102

Chain	Residue
B	ASP35
E	DC21

site_id	CC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE NA C 3103

Chain	Residue
C	ASP35
E	DC16

site_id	DC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE NA D 4104

Chain	Residue
D	ASP35
D	HOH4111
F	DC24

site_id	DC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE NA G 5105

Chain	Residue
G	ASP35
L	DC19
L	HOH35
L	HOH42

site_id	DC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE NA H 6106

Chain	Residue
H	ASP35
H	HOH6109
K	DC21

site_id	DC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE NA I 7107

Chain	Residue
I	ASP35
K	DC16

site_id	DC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE NA J 8108

Chain	Residue
J	ASP35
L	DC24
L	HOH36

Functional Information from PROSITE/UniProt

site_id	PS00142
Number of Residues	10
Details	ZINC_PROTEASE Neutral zinc metallopeptidases, zinc-binding region signature. TLPHEMAHAV

Chain	Residue	Details
A	THR216-VAL225

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	488
Details	Domain: {"description":"HTH dtxR-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU00296","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)