1U7U

Phosphopantothenoylcysteine synthetase from E. coli

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004632	molecular_function	phosphopantothenate--cysteine ligase activity
A	0004633	molecular_function	phosphopantothenoylcysteine decarboxylase activity
A	0010181	molecular_function	FMN binding
A	0015937	biological_process	coenzyme A biosynthetic process
A	0015941	biological_process	pantothenate catabolic process

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	7
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_02225, ECO:0000269|PubMed:15530362, ECO:0007744|PDB:1U7W

Chain	Residue	Details
A	CYS274
A	TYR280
A	ILE290
A	ASP309
A	ALA328
A	ARG342
A	ASN346

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Catalytic Information from CSA

site_id	CSA1
Number of Residues	1
Details	a catalytic site defined by CSA, PubMed 15530362

Chain	Residue	Details
A	ASP210

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site_id	MCSA1
Number of Residues	1
Details	M-CSA 772

Chain	Residue	Details
A	HIS211	activator, electrostatic stabiliser

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