1U3E

DNA binding and cleavage by the HNH homing endonuclease I-HmuI

Functional Information from GO Data

Chain	GOid	namespace	contents
M	0004519	molecular_function	endonuclease activity
M	0006314	biological_process	intron homing
M	0016788	molecular_function	hydrolase activity, acting on ester bonds

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MN M 413

Chain	Residue
B	DC22
C	DG23
M	ASP74
M	ASN96
M	HOH420
M	HOH421

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site_id	AC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE SR A 414

Chain	Residue
B	EDO403

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site_id	AC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE SR A 415

Chain	Residue
B	HOH405

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site_id	AC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SR M 417

Chain	Residue
M	GLN120
M	SR418
M	LYS118

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site_id	AC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SR M 418

Chain	Residue
B	HOH404
M	LYS118
M	SR417

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site_id	AC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO C 397

Chain	Residue
C	DG27
C	DG28
M	GLY50
M	THR52

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site_id	AC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO M 398

Chain	Residue
B	DT8
M	ARG160
M	ILE161
M	HIS162

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site_id	AC8
Number of Residues	2
Details	BINDING SITE FOR RESIDUE EDO M 399

Chain	Residue
M	PRO128
M	HOH427

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site_id	AC9
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EDO M 400

Chain	Residue
M	LYS7
M	HIS62
M	CYS64
M	GLU65
M	GLU134

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site_id	BC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO A 401

Chain	Residue
A	DA20
A	DG21
A	HOH416
B	DG16

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site_id	BC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EDO B 403

Chain	Residue
A	DC27
A	DC28
A	SR414
B	DA12
B	DA13

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site_id	BC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE TRS M 404

Chain	Residue
M	TRP3
M	GLN14
M	ASP129
M	HOH430
M	HOH432

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