1U3C

Crystal Structure of the PHR domain of Cryptochrome 1 from Arabidopsis thaliana

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0009785	biological_process	blue light signaling pathway
A	0009882	molecular_function	blue light photoreceptor activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG A 514

Chain	Residue
A	ASP359
A	FAD510
A	HEZ518
A	HOH579
A	HOH580

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site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG A 515

Chain	Residue
A	ASN238
A	THR246
A	HIS358
A	MG516

---

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG A 516

Chain	Residue
A	LYS241
A	SER244
A	THR246
A	MG515

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site_id	AC4
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL A 517

Chain	Residue
A	HIS318

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site_id	AC5
Number of Residues	26
Details	BINDING SITE FOR RESIDUE FAD A 510

Chain	Residue
A	TYR235
A	THR247
A	SER248
A	PHE249
A	LEU250
A	SER251
A	LEU254
A	PHE290
A	SER293
A	ARG297
A	TRP356
A	ASP359
A	ARG362
A	VAL363
A	SER366
A	LEU388
A	ASP390
A	ALA391
A	ASP392
A	SER395
A	ASP396
A	MG514
A	HEZ518
A	HOH520
A	HOH521
A	HOH539

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site_id	AC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE NDS A 512

Chain	Residue
A	ALA212
A	TRP213
A	SER214
A	ALA223
A	PHE249
A	HIS253

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site_id	AC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE HEZ A 518

Chain	Residue
A	SER395
A	LEU398
A	GLY399
A	TYR402
A	FAD510
A	MG514

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Functional Information from PROSITE/UniProt

site_id	PS00394
Number of Residues	13
Details	DNA_PHOTOLYASES_1_1 DNA photolyases class 1 signature 1. TGyPLVDAgMReL

Chain	Residue	Details
A	THR339-LEU351

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site_id	PS00691
Number of Residues	20
Details	DNA_PHOTOLYASES_1_2 DNA photolyases class 1 signature 2. DRiRVVvSSFFvKvLqlpWR

Chain	Residue	Details
A	ASP359-ARG378

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	BINDING: BINDING => ECO:0000269|PubMed:15299148, ECO:0007744|PDB:1U3C, ECO:0007744|PDB:1U3D

Chain	Residue	Details
A	TYR235
A	SER244
A	THR246
A	THR247
A	ASP359
A	ASP390

---

site_id	SWS_FT_FI2
Number of Residues	3
Details	BINDING: BINDING => ECO:0000269|PubMed:15299148, ECO:0007744|PDB:1U3C

Chain	Residue	Details
A	ASN238
A	LYS241
A	HIS358

---

site_id	SWS_FT_FI3
Number of Residues	3
Details	BINDING: BINDING => ECO:0000269|PubMed:15299148, ECO:0007744|PDB:1U3D

Chain	Residue	Details
A	ARG239
A	SER293
A	ASP409

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	SITE: Involved in electron transfer from the protein surface to the FAD cofactor => ECO:0000269|PubMed:26313597, ECO:0000303|PubMed:22421133

Chain	Residue	Details
A	TRP324
A	TRP400

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site_id	SWS_FT_FI5
Number of Residues	1
Details	SITE: Involved in electron transfer from the protein surface to the FAD cofactor => ECO:0000303|PubMed:22421133

Chain	Residue	Details
A	TRP377

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