1U12

M. loti cyclic nucleotide binding domain mutant

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005221	molecular_function	intracellularly cyclic nucleotide-activated monoatomic cation channel activity
B	0005221	molecular_function	intracellularly cyclic nucleotide-activated monoatomic cation channel activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD B 211

Chain	Residue
B	ALA242

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site_id	AC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD A 356

Chain	Residue
A	LYS238

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site_id	AC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IOD A 411

Chain	Residue
A	ARG271
B	ARG307

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site_id	AC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IOD A 511

Chain	Residue
A	SER281
A	PRO287

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site_id	AC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IOD A 611

Chain	Residue
A	ARG307
B	ARG271

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site_id	AC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IOD A 711

Chain	Residue
A	ARG249
A	PHE223

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site_id	AC7
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD A 811

Chain	Residue
A	LEU229

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site_id	AC8
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD B 911

Chain	Residue
B	PRO234

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site_id	AC9
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD B 112

Chain	Residue
B	GLY221

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site_id	BC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IOD B 122

Chain	Residue
A	PRO257
B	THR255

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site_id	BC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IOD A 132

Chain	Residue
A	ALA325
A	GLN328

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site_id	BC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD A 142

Chain	Residue
A	PRO234

---

site_id	BC4
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD A 192

Chain	Residue
A	SER303

---

site_id	BC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IOD B 212

Chain	Residue
A	THR255
B	THR255

---

site_id	BC6
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD A 812

Chain	Residue
A	GLU347

---

site_id	BC7
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD B 913

Chain	Residue
B	PRO306

---

site_id	BC8
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IOD B 914

Chain	Residue
B	PHE223
B	IOD918

---

site_id	BC9
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD B 915

Chain	Residue
B	HOH8

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site_id	CC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE IOD B 916

Chain	Residue
A	SO4145
A	ARG254
B	PHE273

---

site_id	CC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IOD B 918

Chain	Residue
B	ARG249
B	IOD914

---

site_id	CC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD B 919

Chain	Residue
B	GLN328

---

site_id	CC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 A 144

Chain	Residue
A	CYS263
A	GLY297
A	ARG307
A	SER308
A	ALA309
A	K455

---

site_id	CC5
Number of Residues	7
Details	BINDING SITE FOR RESIDUE SO4 A 145

Chain	Residue
A	ARG254
A	ARG271
A	PHE273
A	SER321
B	ARG254
B	ARG271
B	IOD916

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site_id	CC6
Number of Residues	1
Details	BINDING SITE FOR RESIDUE K A 155

Chain	Residue
A	GLY291

---

site_id	CC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE K B 920

Chain	Residue
B	PRO287
B	PRO287

---

site_id	CC8
Number of Residues	1
Details	BINDING SITE FOR RESIDUE K A 814

Chain	Residue
A	SER279

---

site_id	CC9
Number of Residues	1
Details	BINDING SITE FOR RESIDUE K A 455

Chain	Residue
A	SO4144

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Functional Information from PROSITE/UniProt

site_id	PS00888
Number of Residues	17
Details	CNMP_BINDING_1 Cyclic nucleotide-binding domain signature 1. ICrIGEpGDrMFFVveG

Chain	Residue	Details
A	ILE262-GLY278

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site_id	PS00889
Number of Residues	18
Details	CNMP_BINDING_2 Cyclic nucleotide-binding domain signature 2. FGEmALisgep......RSAtVsA

Chain	Residue	Details
A	PHE296-ALA313

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	5
Details	Binding site: {"evidences":[{"source":"PDB","id":"1VP6","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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