1U0U

An Aldol Switch Discovered in Stilbene Synthases Mediates Cyclization Specificity of Type III Polyketide Synthases: Pine stilbene synthase structure

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005737	cellular_component	cytoplasm
A	0009058	biological_process	biosynthetic process
A	0016746	molecular_function	acyltransferase activity
A	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
A	0030639	biological_process	polyketide biosynthetic process
A	0050198	molecular_function	pinosylvin synthase activity
B	0005737	cellular_component	cytoplasm
B	0009058	biological_process	biosynthetic process
B	0016746	molecular_function	acyltransferase activity
B	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
B	0030639	biological_process	polyketide biosynthetic process
B	0050198	molecular_function	pinosylvin synthase activity
C	0005737	cellular_component	cytoplasm
C	0009058	biological_process	biosynthetic process
C	0016746	molecular_function	acyltransferase activity
C	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
C	0030639	biological_process	polyketide biosynthetic process
C	0050198	molecular_function	pinosylvin synthase activity
D	0005737	cellular_component	cytoplasm
D	0009058	biological_process	biosynthetic process
D	0016746	molecular_function	acyltransferase activity
D	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
D	0030639	biological_process	polyketide biosynthetic process
D	0050198	molecular_function	pinosylvin synthase activity
E	0005737	cellular_component	cytoplasm
E	0009058	biological_process	biosynthetic process
E	0016746	molecular_function	acyltransferase activity
E	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
E	0030639	biological_process	polyketide biosynthetic process
E	0050198	molecular_function	pinosylvin synthase activity
F	0005737	cellular_component	cytoplasm
F	0009058	biological_process	biosynthetic process
F	0016746	molecular_function	acyltransferase activity
F	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
F	0030639	biological_process	polyketide biosynthetic process
F	0050198	molecular_function	pinosylvin synthase activity

Functional Information from PROSITE/UniProt

site_id	PS00441
Number of Residues	17
Details	CHALCONE_SYNTH Chalcone and stilbene synthases active site. RVgVfQhGCFAGGTvLR

Chain	Residue	Details
A	ARG159-ARG175

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	ACT_SITE: ACT_SITE => ECO:0000255|PROSITE-ProRule:PRU10023

Chain	Residue	Details
A	CYS167
B	CYS167
C	CYS167
D	CYS167
E	CYS167
F	CYS167

---

site_id	SWS_FT_FI2
Number of Residues	18
Details	BINDING:

Chain	Residue	Details
A	LYS57
D	LYS57
D	LEU270
D	GLY308
E	LYS57
E	LEU270
E	GLY308
F	LYS57
F	LEU270
F	GLY308
A	LEU270
A	GLY308
B	LYS57
B	LEU270
B	GLY308
C	LYS57
C	LEU270
C	GLY308

---

Catalytic Information from CSA

site_id	CSA1
Number of Residues	4
Details	Annotated By Reference To The Literature 1cgk

Chain	Residue	Details
A	HIS306
A	ASN339
A	PHE218
A	CYS167

---

site_id	CSA2
Number of Residues	4
Details	Annotated By Reference To The Literature 1cgk

Chain	Residue	Details
B	HIS306
B	ASN339
B	PHE218
B	CYS167

---

site_id	CSA3
Number of Residues	4
Details	Annotated By Reference To The Literature 1cgk

Chain	Residue	Details
C	HIS306
C	ASN339
C	PHE218
C	CYS167

---

site_id	CSA4
Number of Residues	4
Details	Annotated By Reference To The Literature 1cgk

Chain	Residue	Details
D	HIS306
D	ASN339
D	PHE218
D	CYS167

---

site_id	CSA5
Number of Residues	4
Details	Annotated By Reference To The Literature 1cgk

Chain	Residue	Details
E	HIS306
E	ASN339
E	PHE218
E	CYS167

---

site_id	CSA6
Number of Residues	4
Details	Annotated By Reference To The Literature 1cgk

Chain	Residue	Details
F	HIS306
F	ASN339
F	PHE218
F	CYS167

---