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1TYG

Structure of the thiazole synthase/ThiS complex

Functional Information from GO Data
ChainGOidnamespacecontents
A0005737cellular_componentcytoplasm
A0009228biological_processthiamine biosynthetic process
A0009229biological_processthiamine diphosphate biosynthetic process
A0016740molecular_functiontransferase activity
A0016783molecular_functionsulfurtransferase activity
A1902508cellular_component2-iminoacetate synthase complex
A1990107molecular_functionthiazole synthase activity
B0000166molecular_functionnucleotide binding
B0009228biological_processthiamine biosynthetic process
B0009229biological_processthiamine diphosphate biosynthetic process
B0052837biological_processthiazole biosynthetic process
B0097163molecular_functionsulfur carrier activity
B1902503cellular_componentadenylyltransferase complex
C0005737cellular_componentcytoplasm
C0009228biological_processthiamine biosynthetic process
C0009229biological_processthiamine diphosphate biosynthetic process
C0016740molecular_functiontransferase activity
C0016783molecular_functionsulfurtransferase activity
C1902508cellular_component2-iminoacetate synthase complex
C1990107molecular_functionthiazole synthase activity
G0000166molecular_functionnucleotide binding
G0009228biological_processthiamine biosynthetic process
G0009229biological_processthiamine diphosphate biosynthetic process
G0052837biological_processthiazole biosynthetic process
G0097163molecular_functionsulfur carrier activity
G1902503cellular_componentadenylyltransferase complex
Functional Information from PDB Data
site_idAC1
Number of Residues6
DetailsBINDING SITE FOR RESIDUE PO4 A 1400
ChainResidue
AILE258
AGLY259
AALA285
AGLY286
AASN307
ATHR308

site_idAC2
Number of Residues7
DetailsBINDING SITE FOR RESIDUE PO4 C 2400
ChainResidue
CILE287
CLEU306
CASN307
CTHR308
CILE258
CALA285
CGLY286

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsActive site: {"description":"Schiff-base intermediate with DXP"}
ChainResidueDetails

site_idSWS_FT_FI2
Number of Residues6
DetailsBinding site: {}
ChainResidueDetails

247536

PDB entries from 2026-01-14

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