1TYG

Structure of the thiazole synthase/ThiS complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005737	cellular_component	cytoplasm
A	0009228	biological_process	thiamine biosynthetic process
A	0009229	biological_process	thiamine diphosphate biosynthetic process
A	0016740	molecular_function	transferase activity
A	0016783	molecular_function	sulfurtransferase activity
A	1990107	molecular_function	thiazole synthase activity
B	0000166	molecular_function	nucleotide binding
B	0009228	biological_process	thiamine biosynthetic process
B	0009229	biological_process	thiamine diphosphate biosynthetic process
C	0005737	cellular_component	cytoplasm
C	0009228	biological_process	thiamine biosynthetic process
C	0009229	biological_process	thiamine diphosphate biosynthetic process
C	0016740	molecular_function	transferase activity
C	0016783	molecular_function	sulfurtransferase activity
C	1990107	molecular_function	thiazole synthase activity
G	0000166	molecular_function	nucleotide binding
G	0009228	biological_process	thiamine biosynthetic process
G	0009229	biological_process	thiamine diphosphate biosynthetic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE PO4 A 1400

Chain	Residue
A	ILE258
A	GLY259
A	ALA285
A	GLY286
A	ASN307
A	THR308

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site_id	AC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE PO4 C 2400

Chain	Residue
C	ILE287
C	LEU306
C	ASN307
C	THR308
C	ILE258
C	ALA285
C	GLY286

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	ACT_SITE: Schiff-base intermediate with DXP

Chain	Residue	Details
A	LYS198
C	LYS198

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site_id	SWS_FT_FI2
Number of Residues	6
Details	BINDING:

Chain	Residue	Details
A	GLY259
A	ALA285
A	ASN307
C	GLY259
C	ALA285
C	ASN307

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