1TXF

CRYSTAL STRUCTURE OF THE GLUR5 LIGAND BINDING CORE IN COMPLEX WITH GLUTAMATE AT 2.1 ANGSTROM RESOLUTION

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0015276	molecular_function	ligand-gated monoatomic ion channel activity
A	0016020	cellular_component	membrane

Functional Information from PDB Data

site_id	AC1
Number of Residues	12
Details	BINDING SITE FOR RESIDUE GLU A 259

Chain	Residue
A	TYR61
A	HOH293
A	HOH299
A	HOH309
A	PRO88
A	LEU89
A	THR90
A	ARG95
A	GLY140
A	SER141
A	THR142
A	GLU190

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	BINDING: BINDING => ECO:0000269|PubMed:15710405, ECO:0007744|PDB:1YCJ

Chain	Residue	Details
A	PRO88
A	SER141
A	THR142
A	THR90

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site_id	SWS_FT_FI2
Number of Residues	2
Details	BINDING: BINDING => ECO:0000269|PubMed:15710405, ECO:0000269|PubMed:15721240, ECO:0007744|PDB:1YCJ

Chain	Residue	Details
A	GLU190
A	ARG95

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site_id	SWS_FT_FI3
Number of Residues	1
Details	MOD_RES: Phosphoserine; by PKC => ECO:0000255

Chain	Residue	Details
A	SER162

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site_id	SWS_FT_FI4
Number of Residues	1
Details	MOD_RES: Phosphothreonine; by PKC => ECO:0000255

Chain	Residue	Details
A	THR198

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site_id	SWS_FT_FI5
Number of Residues	2
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255

Chain	Residue	Details
A	ASN3
A	ASN203

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