1TW8
HincII bound to Ca2+ and cognate DNA GTCGAC
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003677 | molecular_function | DNA binding |
| A | 0004518 | molecular_function | nuclease activity |
| A | 0004519 | molecular_function | endonuclease activity |
| A | 0009036 | molecular_function | type II site-specific deoxyribonuclease activity |
| A | 0009307 | biological_process | DNA restriction-modification system |
| A | 0016787 | molecular_function | hydrolase activity |
| B | 0003677 | molecular_function | DNA binding |
| B | 0004518 | molecular_function | nuclease activity |
| B | 0004519 | molecular_function | endonuclease activity |
| B | 0009036 | molecular_function | type II site-specific deoxyribonuclease activity |
| B | 0009307 | biological_process | DNA restriction-modification system |
| B | 0016787 | molecular_function | hydrolase activity |
| C | 0003677 | molecular_function | DNA binding |
| C | 0004518 | molecular_function | nuclease activity |
| C | 0004519 | molecular_function | endonuclease activity |
| C | 0009036 | molecular_function | type II site-specific deoxyribonuclease activity |
| C | 0009307 | biological_process | DNA restriction-modification system |
| C | 0016787 | molecular_function | hydrolase activity |
| D | 0003677 | molecular_function | DNA binding |
| D | 0004518 | molecular_function | nuclease activity |
| D | 0004519 | molecular_function | endonuclease activity |
| D | 0009036 | molecular_function | type II site-specific deoxyribonuclease activity |
| D | 0009307 | biological_process | DNA restriction-modification system |
| D | 0016787 | molecular_function | hydrolase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 801 |
| Chain | Residue |
| A | ASP114 |
| A | ASP127 |
| A | VAL128 |
| A | HOH1058 |
| F | DG8 |
| F | HOH806 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA B 802 |
| Chain | Residue |
| B | HOH1006 |
| E | DG8 |
| E | HOH244 |
| B | ASP114 |
| B | ASP127 |
| B | VAL128 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CA C 803 |
| Chain | Residue |
| C | ASP114 |
| C | ASP127 |
| C | VAL128 |
| C | HOH971 |
| H | DG8 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CA D 804 |
| Chain | Residue |
| D | ASP114 |
| D | ASP127 |
| D | VAL128 |
| D | HOH922 |
| G | DG8 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE CA F 805 |
| Chain | Residue |
| B | HOH1059 |
| E | DG12 |
| F | DG1 |
| F | DG1 |
| F | DC2 |
| F | HOH841 |
| F | HOH841 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CA H 806 |
| Chain | Residue |
| H | DG1 |
| H | DG1 |
| H | HOH43 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA A 901 |
| Chain | Residue |
| A | ASP127 |
| A | LYS129 |
| A | ILE142 |
| A | HOH1060 |
| A | HOH1066 |
| F | DG8 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA B 902 |
| Chain | Residue |
| B | ASP127 |
| B | LYS129 |
| B | ILE142 |
| B | HOH976 |
| B | HOH998 |
| E | DG8 |
| site_id | AC9 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE NA C 903 |
| Chain | Residue |
| C | ASP127 |
| C | LYS129 |
| C | ILE142 |
| C | ILE143 |
| C | HOH967 |
| H | DC7 |
| H | DG8 |
| site_id | BC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA D 904 |
| Chain | Residue |
| D | ASP127 |
| D | LYS129 |
| D | ILE142 |
| D | HOH989 |
| G | DG8 |
| G | HOH551 |
