1TTU
Crystal Structure of CSL bound to DNA
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000978 | molecular_function | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
| A | 0001228 | molecular_function | DNA-binding transcription activator activity, RNA polymerase II-specific |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003700 | molecular_function | DNA-binding transcription factor activity |
| A | 0005634 | cellular_component | nucleus |
| A | 0006355 | biological_process | regulation of DNA-templated transcription |
| A | 0006357 | biological_process | regulation of transcription by RNA polymerase II |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO A 51 |
| Chain | Residue |
| A | PHE220 |
| A | TYR243 |
| A | ILE245 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO A 52 |
| Chain | Residue |
| A | LEU654 |
| A | PRO639 |
| A | ILE640 |
| A | SER641 |
| A | SER651 |
| A | SER652 |
| A | GLY653 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 53 |
| Chain | Residue |
| A | CYS241 |
| A | TYR243 |
| A | TRP422 |
| A | VAL461 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO A 54 |
| Chain | Residue |
| A | EDO55 |
| A | ALA544 |
| A | GLU545 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE EDO A 55 |
| Chain | Residue |
| A | EDO54 |
| A | ARG584 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 56 |
| Chain | Residue |
| A | EDO58 |
| A | VAL224 |
| A | GLN226 |
| A | PHE236 |
| A | CYS237 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO A 57 |
| Chain | Residue |
| A | PHE395 |
| A | ASN396 |
| A | ARG397 |
| A | LYS495 |
| A | ALA535 |
| A | THR537 |
| B | DG8 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 58 |
| Chain | Residue |
| A | EDO56 |
| A | GLN226 |
| A | ARG234 |
| A | PHE235 |
| B | DT7 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 96 |
| Details | Domain: {"description":"IPT/TIG","evidences":[{"source":"UniProtKB","id":"Q06330","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 20 |
| Details | Region: {"description":"DNA-binding","evidences":[{"source":"PubMed","id":"15297877","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16530045","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
