Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

1TTT

Phe-tRNA, elongation factoR EF-TU:GDPNP ternary complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0000287	molecular_function	magnesium ion binding
A	0003746	molecular_function	translation elongation factor activity
A	0003924	molecular_function	GTPase activity
A	0005525	molecular_function	GTP binding
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006412	biological_process	translation
A	0006414	biological_process	translational elongation
A	0016787	molecular_function	hydrolase activity
A	0046872	molecular_function	metal ion binding
B	0000166	molecular_function	nucleotide binding
B	0000287	molecular_function	magnesium ion binding
B	0003746	molecular_function	translation elongation factor activity
B	0003924	molecular_function	GTPase activity
B	0005525	molecular_function	GTP binding
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0006412	biological_process	translation
B	0006414	biological_process	translational elongation
B	0016787	molecular_function	hydrolase activity
B	0046872	molecular_function	metal ion binding
C	0000166	molecular_function	nucleotide binding
C	0000287	molecular_function	magnesium ion binding
C	0003746	molecular_function	translation elongation factor activity
C	0003924	molecular_function	GTPase activity
C	0005525	molecular_function	GTP binding
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0006412	biological_process	translation
C	0006414	biological_process	translational elongation
C	0016787	molecular_function	hydrolase activity
C	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG A 407

Chain	Residue
A	THR25
A	ASP51
A	THR62
A	GNP406
A	HOH410

site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG B 407

Chain	Residue
B	HOH409
B	THR25
B	ASP51
B	THR62
B	GNP406

site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG C 407

Chain	Residue
C	THR25
C	TYR47
C	ASP51
C	THR62
C	GNP406

site_id	AC4
Number of Residues	10
Details	BINDING SITE FOR RESIDUE PHE D 77

Chain	Residue
A	HIS67
A	GLU226
A	THR239
A	GLU271
A	MET272
A	HIS273
A	ARG274
A	ASN285
A	VAL286
D	A76

site_id	AC5
Number of Residues	10
Details	BINDING SITE FOR RESIDUE PHE E 77

Chain	Residue
B	HIS67
B	GLU226
B	THR239
B	GLU271
B	MET272
B	HIS273
B	ARG274
B	ASN285
B	VAL286
E	A76

site_id	AC6
Number of Residues	10
Details	BINDING SITE FOR RESIDUE PHE F 77

Chain	Residue
C	HIS67
C	GLU226
C	THR239
C	GLU271
C	MET272
C	HIS273
C	ARG274
C	ASN285
C	VAL286
F	A76

site_id	AC7
Number of Residues	20
Details	BINDING SITE FOR RESIDUE GNP A 406

Chain	Residue
A	VAL20
A	ASP21
A	HIS22
A	GLY23
A	LYS24
A	THR25
A	THR26
A	TYR47
A	ILE61
A	THR62
A	GLY84
A	ASN136
A	LYS137
A	ASP139
A	MET140
A	SER174
A	ALA175
A	LEU176
A	MG407
A	HOH410

site_id	AC8
Number of Residues	20
Details	BINDING SITE FOR RESIDUE GNP B 406

Chain	Residue
B	VAL20
B	ASP21
B	HIS22
B	GLY23
B	LYS24
B	THR25
B	THR26
B	TYR47
B	ILE61
B	THR62
B	GLY84
B	ASN136
B	LYS137
B	ASP139
B	MET140
B	SER174
B	ALA175
B	LEU176
B	MG407
B	HOH409

site_id	AC9
Number of Residues	19
Details	BINDING SITE FOR RESIDUE GNP C 406

Chain	Residue
C	MET140
C	SER174
C	ALA175
C	LEU176
C	MG407
C	VAL20
C	ASP21
C	HIS22
C	GLY23
C	LYS24
C	THR25
C	THR26
C	TYR47
C	ILE61
C	THR62
C	GLY84
C	ASN136
C	LYS137
C	ASP139

Functional Information from PROSITE/UniProt

site_id	PS00301
Number of Residues	16
Details	G_TR_1 Translational (tr)-type guanine nucleotide-binding (G) domain signature. DKapeERaRGITIntA

Chain	Residue	Details
A	ASP51-ALA66

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	615
Details	Domain: {"description":"tr-type G"}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	21
Details	Region: {"description":"G1","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	12
Details	Region: {"description":"G2","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI4
Number of Residues	9
Details	Region: {"description":"G3","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI5
Number of Residues	9
Details	Region: {"description":"G4","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI6
Number of Residues	6
Details	Region: {"description":"G5","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI7
Number of Residues	42
Details	Binding site: {}

Chain

Residue

Details

site_id	SWS_FT_FI8
Number of Residues	3
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00118","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

Catalytic Information from CSA

site_id	CSA1
Number of Residues	1
Details	Annotated By Reference To The Literature 1ksj

Chain	Residue	Details
A	ASP21

site_id	CSA2
Number of Residues	1
Details	Annotated By Reference To The Literature 1ksj

Chain	Residue	Details
B	ASP21

site_id	CSA3
Number of Residues	1
Details	Annotated By Reference To The Literature 1ksj

Chain	Residue	Details
C	ASP21

site_id	CSA4
Number of Residues	1
Details	Annotated By Reference To The Literature 1ksj

Chain	Residue	Details
A	HIS85

site_id	CSA5
Number of Residues	1
Details	Annotated By Reference To The Literature 1ksj

Chain	Residue	Details
B	HIS85

site_id	CSA6
Number of Residues	1
Details	Annotated By Reference To The Literature 1ksj

Chain	Residue	Details
C	HIS85

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)