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1TTL

Omega-conotoxin GVIA, a N-type calcium channel blocker

Functional Information from GO Data
ChainGOidnamespacecontents
A0005576cellular_componentextracellular region
A0008200molecular_functionion channel inhibitor activity
Functional Information from PDB Data
site_idAC1
Number of Residues2
DetailsBINDING SITE FOR RESIDUE NH2 A 28
ChainResidue
ASER3
ATYR27

Functional Information from PROSITE/UniProt
site_idPS60004
Number of Residues26
DetailsOMEGA_CONOTOXIN Omega-conotoxin family signature. CKspGsSCSpt...SYnCCR..SCnpyTKRC
ChainResidueDetails
ACYS1-CYS26

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues3
DetailsMOD_RES: 4-hydroxyproline => ECO:0000269|PubMed:6509012
ChainResidueDetails
AHYP4
AHYP10
AHYP21

site_idSWS_FT_FI2
Number of Residues1
DetailsMOD_RES: Tyrosine amide; in form omega-conotoxin GVIA => ECO:0000269|PubMed:6509012
ChainResidueDetails
ATYR27

227111

PDB entries from 2024-11-06

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