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1TT9

Structure of the bifunctional and Golgi associated formiminotransferase cyclodeaminase octamer

Functional Information from GO Data
ChainGOidnamespacecontents
A0000139cellular_componentGolgi membrane
A0003824molecular_functioncatalytic activity
A0005542molecular_functionfolic acid binding
A0005737cellular_componentcytoplasm
A0005783cellular_componentendoplasmic reticulum
A0005793cellular_componentendoplasmic reticulum-Golgi intermediate compartment
A0005794cellular_componentGolgi apparatus
A0005814cellular_componentcentriole
A0005829cellular_componentcytosol
A0005856cellular_componentcytoskeleton
A0005886cellular_componentplasma membrane
A0006547biological_processL-histidine metabolic process
A0007010biological_processcytoskeleton organization
A0008017molecular_functionmicrotubule binding
A0016740molecular_functiontransferase activity
A0016829molecular_functionlyase activity
A0019215molecular_functionintermediate filament binding
A0019556biological_processL-histidine catabolic process to glutamate and formamide
A0019557biological_processL-histidine catabolic process to glutamate and formate
A0030409molecular_functionglutamate formimidoyltransferase activity
A0030412molecular_functionformimidoyltetrahydrofolate cyclodeaminase activity
A0030868cellular_componentsmooth endoplasmic reticulum membrane
A0044237biological_processcellular metabolic process
B0000139cellular_componentGolgi membrane
B0003824molecular_functioncatalytic activity
B0005542molecular_functionfolic acid binding
B0005737cellular_componentcytoplasm
B0005783cellular_componentendoplasmic reticulum
B0005793cellular_componentendoplasmic reticulum-Golgi intermediate compartment
B0005794cellular_componentGolgi apparatus
B0005814cellular_componentcentriole
B0005829cellular_componentcytosol
B0005856cellular_componentcytoskeleton
B0005886cellular_componentplasma membrane
B0006547biological_processL-histidine metabolic process
B0007010biological_processcytoskeleton organization
B0008017molecular_functionmicrotubule binding
B0016740molecular_functiontransferase activity
B0016829molecular_functionlyase activity
B0019215molecular_functionintermediate filament binding
B0019556biological_processL-histidine catabolic process to glutamate and formamide
B0019557biological_processL-histidine catabolic process to glutamate and formate
B0030409molecular_functionglutamate formimidoyltransferase activity
B0030412molecular_functionformimidoyltetrahydrofolate cyclodeaminase activity
B0030868cellular_componentsmooth endoplasmic reticulum membrane
B0044237biological_processcellular metabolic process
C0000139cellular_componentGolgi membrane
C0003824molecular_functioncatalytic activity
C0005542molecular_functionfolic acid binding
C0005737cellular_componentcytoplasm
C0005783cellular_componentendoplasmic reticulum
C0005793cellular_componentendoplasmic reticulum-Golgi intermediate compartment
C0005794cellular_componentGolgi apparatus
C0005814cellular_componentcentriole
C0005829cellular_componentcytosol
C0005856cellular_componentcytoskeleton
C0005886cellular_componentplasma membrane
C0006547biological_processL-histidine metabolic process
C0007010biological_processcytoskeleton organization
C0008017molecular_functionmicrotubule binding
C0016740molecular_functiontransferase activity
C0016829molecular_functionlyase activity
C0019215molecular_functionintermediate filament binding
C0019556biological_processL-histidine catabolic process to glutamate and formamide
C0019557biological_processL-histidine catabolic process to glutamate and formate
C0030409molecular_functionglutamate formimidoyltransferase activity
C0030412molecular_functionformimidoyltetrahydrofolate cyclodeaminase activity
C0030868cellular_componentsmooth endoplasmic reticulum membrane
C0044237biological_processcellular metabolic process
D0000139cellular_componentGolgi membrane
D0003824molecular_functioncatalytic activity
D0005542molecular_functionfolic acid binding
D0005737cellular_componentcytoplasm
D0005783cellular_componentendoplasmic reticulum
D0005793cellular_componentendoplasmic reticulum-Golgi intermediate compartment
D0005794cellular_componentGolgi apparatus
D0005814cellular_componentcentriole
D0005829cellular_componentcytosol
D0005856cellular_componentcytoskeleton
D0005886cellular_componentplasma membrane
D0006547biological_processL-histidine metabolic process
D0007010biological_processcytoskeleton organization
D0008017molecular_functionmicrotubule binding
D0016740molecular_functiontransferase activity
D0016829molecular_functionlyase activity
D0019215molecular_functionintermediate filament binding
D0019556biological_processL-histidine catabolic process to glutamate and formamide
D0019557biological_processL-histidine catabolic process to glutamate and formate
D0030409molecular_functionglutamate formimidoyltransferase activity
D0030412molecular_functionformimidoyltetrahydrofolate cyclodeaminase activity
D0030868cellular_componentsmooth endoplasmic reticulum membrane
D0044237biological_processcellular metabolic process
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues4
DetailsACT_SITE: For formimidoyltransferase activity => ECO:0000250
ChainResidueDetails
AHIS82
BHIS82
CHIS82
DHIS82

site_idSWS_FT_FI2
Number of Residues4
DetailsACT_SITE: For cyclodeaminase activity => ECO:0000305|PubMed:15272307
ChainResidueDetails
AASP412
BASP412
CASP412
DASP412

site_idSWS_FT_FI3
Number of Residues4
DetailsBINDING: BINDING => ECO:0000255
ChainResidueDetails
AGLY163
BGLY163
CGLY163
DGLY163

site_idSWS_FT_FI4
Number of Residues4
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:22673903
ChainResidueDetails
ASER520
BSER520
CSER520
DSER520

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PDB entries from 2024-10-30

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