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1TRJ

Homology Model of Yeast RACK1 Protein fitted into 11.7A cryo-EM map of Yeast 80S Ribosome

Functional Information from GO Data
ChainGOidnamespacecontents
A0001965molecular_functionG-protein alpha-subunit binding
A0002181biological_processcytoplasmic translation
A0005080molecular_functionprotein kinase C binding
A0005092molecular_functionGDP-dissociation inhibitor activity
A0005634cellular_componentnucleus
A0005737cellular_componentcytoplasm
A0005829cellular_componentcytosol
A0005840cellular_componentribosome
A0006521biological_processregulation of cellular amino acid metabolic process
A0007186biological_processG protein-coupled receptor signaling pathway
A0010629biological_processnegative regulation of gene expression
A0017148biological_processnegative regulation of translation
A0022627cellular_componentcytosolic small ribosomal subunit
A0043022molecular_functionribosome binding
A0045182molecular_functiontranslation regulator activity
A0061157biological_processmRNA destabilization
A0070651biological_processnonfunctional rRNA decay
A0072344biological_processrescue of stalled ribosome
A1902660biological_processnegative regulation of glucose mediated signaling pathway
A1990116biological_processribosome-associated ubiquitin-dependent protein catabolic process
A1990145biological_processmaintenance of translational fidelity
A1990904cellular_componentribonucleoprotein complex
A2001125biological_processnegative regulation of translational frameshifting
Functional Information from PROSITE/UniProt
site_idPS00678
Number of Residues15
DetailsWD_REPEATS_1 Trp-Asp (WD) repeats signature. ALSAswDkTLRLWDV
ChainResidueDetails
AALA80-VAL94
AILE169-LEU183
AILE211-LEU225

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsMOD_RES: N-acetylalanine => ECO:0000269|Ref.3, ECO:0007744|PubMed:22814378
ChainResidueDetails
AALA2

site_idSWS_FT_FI2
Number of Residues1
DetailsMOD_RES: Phosphothreonine => ECO:0007744|PubMed:17287358
ChainResidueDetails
ATHR96

site_idSWS_FT_FI3
Number of Residues1
DetailsMOD_RES: Phosphothreonine => ECO:0007744|PubMed:19779198
ChainResidueDetails
ATHR168

site_idSWS_FT_FI4
Number of Residues6
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0007744|PubMed:22106047
ChainResidueDetails
ALYS46
ALYS53
ALYS107
ALYS137
ALYS161

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PDB entries from 2024-11-06

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