1TRJ
Homology Model of Yeast RACK1 Protein fitted into 11.7A cryo-EM map of Yeast 80S Ribosome
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0001965 | molecular_function | G-protein alpha-subunit binding |
| A | 0002181 | biological_process | cytoplasmic translation |
| A | 0005080 | molecular_function | protein kinase C binding |
| A | 0005092 | molecular_function | GDP-dissociation inhibitor activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0005840 | cellular_component | ribosome |
| A | 0006521 | biological_process | regulation of amino acid metabolic process |
| A | 0007186 | biological_process | G protein-coupled receptor signaling pathway |
| A | 0010629 | biological_process | negative regulation of gene expression |
| A | 0017148 | biological_process | negative regulation of translation |
| A | 0022627 | cellular_component | cytosolic small ribosomal subunit |
| A | 0043022 | molecular_function | ribosome binding |
| A | 0045182 | molecular_function | translation regulator activity |
| A | 0061157 | biological_process | mRNA destabilization |
| A | 0070651 | biological_process | nonfunctional rRNA decay |
| A | 0072344 | biological_process | rescue of stalled ribosome |
| A | 1902660 | biological_process | negative regulation of glucose mediated signaling pathway |
| A | 1990116 | biological_process | ribosome-associated ubiquitin-dependent protein catabolic process |
| A | 1990145 | biological_process | maintenance of translational fidelity |
| A | 1990904 | cellular_component | ribonucleoprotein complex |
| A | 2001125 | biological_process | negative regulation of translational frameshifting |
Functional Information from PROSITE/UniProt
| site_id | PS00678 |
| Number of Residues | 15 |
| Details | WD_REPEATS_1 Trp-Asp (WD) repeats signature. ALSAswDkTLRLWDV |
| Chain | Residue | Details |
| A | ALA80-VAL94 | |
| A | ILE169-LEU183 | |
| A | ILE211-LEU225 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 40 |
| Details | Repeat: {"description":"WD 1"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 39 |
| Details | Repeat: {"description":"WD 2"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 40 |
| Details | Repeat: {"description":"WD 3"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 44 |
| Details | Repeat: {"description":"WD 4"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 39 |
| Details | Repeat: {"description":"WD 5"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 40 |
| Details | Repeat: {"description":"WD 6"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"N-acetylalanine","evidences":[{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"MAY-2005","submissionDatabase":"UniProtKB","authors":["Bienvenut W.V.","Peters C."]}},{"source":"PubMed","id":"22814378","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"17287358","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"19779198","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI10 |
| Number of Residues | 6 |
| Details | Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"PubMed","id":"22106047","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
