Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003676 | molecular_function | nucleic acid binding |
| A | 0003964 | molecular_function | RNA-directed DNA polymerase activity |
| A | 0004523 | molecular_function | RNA-DNA hybrid ribonuclease activity |
| A | 0006278 | biological_process | RNA-templated DNA biosynthetic process |
| B | 0003964 | molecular_function | RNA-directed DNA polymerase activity |
| B | 0006278 | biological_process | RNA-templated DNA biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE PO4 A 1300 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PO4 A 1301 |
| Chain | Residue |
| A | GLY436 |
| A | ASN460 |
| A | ARG461 |
| B | GLU79 |
| B | ALA288 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PO4 A 1302 |
| Chain | Residue |
| A | GLN151 |
| A | MET41 |
| A | PHE116 |
| A | TYR146 |
| site_id | AC4 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE H18 A 999 |
| Chain | Residue |
| A | LEU100 |
| A | LYS101 |
| A | VAL106 |
| A | VAL179 |
| A | TYR181 |
| A | TYR188 |
| A | PRO225 |
| A | PHE227 |
| A | TRP229 |
| A | LEU234 |
| A | HIS235 |
| A | PRO236 |
| A | TYR318 |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| B | HIS235-TRP252 | |
| Chain | Residue | Details |
| B | ASP256-GLY273 | |
| Chain | Residue | Details |
| B | ARG358 | |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | SITE: Cis/trans isomerization of proline peptide bond; by human PPIA/CYPA |
| Chain | Residue | Details |
| B | LYS66 | |
| site_id | SWS_FT_FI5 |
| Number of Residues | 4 |
| Details | SITE: Cleavage; by viral protease => ECO:0000250 |
| Chain | Residue | Details |
| B | HIS208 | |
| B | GLN222 | |
| B | GLY285 | |
| B | GLU432 | |
| site_id | SWS_FT_FI6 |
| Number of Residues | 3 |
| Details | SITE: Cleavage; by viral protease => ECO:0000255 |
| Chain | Residue | Details |
| B | LYS238 | |
| B | TYR271 | |
| B | ARG277 | |
| A | GLU432 | |
| Chain | Residue | Details |
| B | GLY333 | |
| A | TYR271 | |
| A | ARG277 | |
| Chain | Residue | Details |
| A | GLY333 | |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 3 |
| Details | M-CSA 175 |
| Chain | Residue | Details |
| B | ARG358 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| B | GLY359 | electrostatic stabiliser, transition state stabiliser |
| B | ALA360 | electrostatic stabiliser, hydrogen bond donor |
