1TL1

CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH GW451211

Experimental procedure

Experimental method	SINGLE WAVELENGTH
Source type	SYNCHROTRON
Source details	ESRF BEAMLINE BM14
Synchrotron site	ESRF
Beamline	BM14
Temperature [K]	100
Detector technology	IMAGE PLATE
Collection date	1997-12-13
Detector	MARRESEARCH
Wavelength(s)	0.918
Spacegroup name	P 21 21 21
Unit cell lengths	137.500, 115.300, 65.400
Unit cell angles	90.00, 90.00, 90.00

Refinement procedure

Resolution	24.910 - 2.900
R-factor	0.221
Rwork	0.221
R-free	0.28100
Structure solution method	MOLECULAR REPLACEMENT
RMSD bond length	0.011
RMSD bond angle	1.600
Data reduction software	DENZO
Data scaling software	SCALEPACK
Phasing software	X-PLOR
Refinement software	CNS (1.1)

Data quality characteristics

	Overall	Outer shell
Low resolution limit [Å]	25.000	2.970
High resolution limit [Å]	2.900	2.900
Rmerge	0.052	0.380
Number of reflections	23603
<I/σ(I)>	19.87	2.45
Completeness [%]	99.0	92.3
Redundancy	3.75	2.87

Crystallization Conditions

crystal ID	method	pH	temperature	details
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