1TBG

BETA-GAMMA DIMER OF THE HETEROTRIMERIC G-PROTEIN TRANSDUCIN

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0001750	cellular_component	photoreceptor outer segment
A	0003924	molecular_function	GTPase activity
A	0005515	molecular_function	protein binding
A	0005737	cellular_component	cytoplasm
A	0005834	cellular_component	heterotrimeric G-protein complex
A	0007165	biological_process	signal transduction
A	0007186	biological_process	G protein-coupled receptor signaling pathway
A	0007191	biological_process	adenylate cyclase-activating dopamine receptor signaling pathway
A	0007200	biological_process	phospholipase C-activating G protein-coupled receptor signaling pathway
A	0008283	biological_process	cell population proliferation
A	0016020	cellular_component	membrane
A	0030159	molecular_function	signaling receptor complex adaptor activity
A	0044877	molecular_function	protein-containing complex binding
A	0045202	cellular_component	synapse
A	0050909	biological_process	sensory perception of taste
A	0051020	molecular_function	GTPase binding
A	0060041	biological_process	retina development in camera-type eye
A	0071380	biological_process	cellular response to prostaglandin E stimulus
A	0071870	biological_process	cellular response to catecholamine stimulus
A	0097381	cellular_component	photoreceptor disc membrane
B	0001750	cellular_component	photoreceptor outer segment
B	0003924	molecular_function	GTPase activity
B	0005515	molecular_function	protein binding
B	0005737	cellular_component	cytoplasm
B	0005834	cellular_component	heterotrimeric G-protein complex
B	0007165	biological_process	signal transduction
B	0007186	biological_process	G protein-coupled receptor signaling pathway
B	0007191	biological_process	adenylate cyclase-activating dopamine receptor signaling pathway
B	0007200	biological_process	phospholipase C-activating G protein-coupled receptor signaling pathway
B	0008283	biological_process	cell population proliferation
B	0016020	cellular_component	membrane
B	0030159	molecular_function	signaling receptor complex adaptor activity
B	0044877	molecular_function	protein-containing complex binding
B	0045202	cellular_component	synapse
B	0050909	biological_process	sensory perception of taste
B	0051020	molecular_function	GTPase binding
B	0060041	biological_process	retina development in camera-type eye
B	0071380	biological_process	cellular response to prostaglandin E stimulus
B	0071870	biological_process	cellular response to catecholamine stimulus
B	0097381	cellular_component	photoreceptor disc membrane
C	0001750	cellular_component	photoreceptor outer segment
C	0003924	molecular_function	GTPase activity
C	0005515	molecular_function	protein binding
C	0005737	cellular_component	cytoplasm
C	0005834	cellular_component	heterotrimeric G-protein complex
C	0007165	biological_process	signal transduction
C	0007186	biological_process	G protein-coupled receptor signaling pathway
C	0007191	biological_process	adenylate cyclase-activating dopamine receptor signaling pathway
C	0007200	biological_process	phospholipase C-activating G protein-coupled receptor signaling pathway
C	0008283	biological_process	cell population proliferation
C	0016020	cellular_component	membrane
C	0030159	molecular_function	signaling receptor complex adaptor activity
C	0044877	molecular_function	protein-containing complex binding
C	0045202	cellular_component	synapse
C	0050909	biological_process	sensory perception of taste
C	0051020	molecular_function	GTPase binding
C	0060041	biological_process	retina development in camera-type eye
C	0071380	biological_process	cellular response to prostaglandin E stimulus
C	0071870	biological_process	cellular response to catecholamine stimulus
C	0097381	cellular_component	photoreceptor disc membrane
D	0001750	cellular_component	photoreceptor outer segment
D	0003924	molecular_function	GTPase activity
D	0005515	molecular_function	protein binding
D	0005737	cellular_component	cytoplasm
D	0005834	cellular_component	heterotrimeric G-protein complex
D	0007165	biological_process	signal transduction
D	0007186	biological_process	G protein-coupled receptor signaling pathway
D	0007191	biological_process	adenylate cyclase-activating dopamine receptor signaling pathway
D	0007200	biological_process	phospholipase C-activating G protein-coupled receptor signaling pathway
D	0008283	biological_process	cell population proliferation
D	0016020	cellular_component	membrane
D	0030159	molecular_function	signaling receptor complex adaptor activity
D	0044877	molecular_function	protein-containing complex binding
D	0045202	cellular_component	synapse
D	0050909	biological_process	sensory perception of taste
D	0051020	molecular_function	GTPase binding
D	0060041	biological_process	retina development in camera-type eye
D	0071380	biological_process	cellular response to prostaglandin E stimulus
D	0071870	biological_process	cellular response to catecholamine stimulus
D	0097381	cellular_component	photoreceptor disc membrane
E	0005834	cellular_component	heterotrimeric G-protein complex
E	0005886	cellular_component	plasma membrane
E	0007165	biological_process	signal transduction
E	0007186	biological_process	G protein-coupled receptor signaling pathway
E	0007602	biological_process	phototransduction
E	0008104	biological_process	protein localization
E	0031681	molecular_function	G-protein beta-subunit binding
E	0042462	biological_process	eye photoreceptor cell development
E	0097381	cellular_component	photoreceptor disc membrane
F	0005834	cellular_component	heterotrimeric G-protein complex
F	0005886	cellular_component	plasma membrane
F	0007165	biological_process	signal transduction
F	0007186	biological_process	G protein-coupled receptor signaling pathway
F	0007602	biological_process	phototransduction
F	0008104	biological_process	protein localization
F	0031681	molecular_function	G-protein beta-subunit binding
F	0042462	biological_process	eye photoreceptor cell development
F	0097381	cellular_component	photoreceptor disc membrane
G	0005834	cellular_component	heterotrimeric G-protein complex
G	0005886	cellular_component	plasma membrane
G	0007165	biological_process	signal transduction
G	0007186	biological_process	G protein-coupled receptor signaling pathway
G	0007602	biological_process	phototransduction
G	0008104	biological_process	protein localization
G	0031681	molecular_function	G-protein beta-subunit binding
G	0042462	biological_process	eye photoreceptor cell development
G	0097381	cellular_component	photoreceptor disc membrane
H	0005834	cellular_component	heterotrimeric G-protein complex
H	0005886	cellular_component	plasma membrane
H	0007165	biological_process	signal transduction
H	0007186	biological_process	G protein-coupled receptor signaling pathway
H	0007602	biological_process	phototransduction
H	0008104	biological_process	protein localization
H	0031681	molecular_function	G-protein beta-subunit binding
H	0042462	biological_process	eye photoreceptor cell development
H	0097381	cellular_component	photoreceptor disc membrane

Functional Information from PROSITE/UniProt

site_id	PS00678
Number of Residues	15
Details	WD_REPEATS_1 Trp-Asp (WD) repeats signature. LVSAsqDgKLIIWDS

Chain	Residue	Details
A	LEU70-SER84
A	ILE157-ILE171
A	LEU285-ALA299

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P62873

Chain	Residue	Details
A	SER2
B	SER2
C	SER2
D	SER2

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site_id	SWS_FT_FI2
Number of Residues	4
Details	MOD_RES: Phosphohistidine => ECO:0000269|PubMed:12486123

Chain	Residue	Details
A	HIS266
B	HIS266
C	HIS266
D	HIS266

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