1T8Q

Structural genomics, Crystal structure of Glycerophosphoryl diester phosphodiesterase from E. coli

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0006629	biological_process	lipid metabolic process
A	0008081	molecular_function	phosphoric diester hydrolase activity
B	0006629	biological_process	lipid metabolic process
B	0008081	molecular_function	phosphoric diester hydrolase activity
C	0006629	biological_process	lipid metabolic process
C	0008081	molecular_function	phosphoric diester hydrolase activity
D	0006629	biological_process	lipid metabolic process
D	0008081	molecular_function	phosphoric diester hydrolase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG A 1601

Chain	Residue
A	GLU63
A	ASP65
A	GLU171
A	GOL1605
A	HOH1615

---

site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG B 1602

Chain	Residue
B	HOH1612
B	GLU63
B	ASP65
B	GLU171
B	GOL1606

---

site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG C 1603

Chain	Residue
C	GLU63
C	ASP65
C	GLU171
C	GOL1607
C	HOH1614

---

site_id	AC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG D 1604

Chain	Residue
D	GLU63
D	ASP65
D	GLU171
D	GOL1608
D	HOH1616

---

site_id	AC5
Number of Residues	12
Details	BINDING SITE FOR RESIDUE GOL A 1605

Chain	Residue
A	HIS36
A	ARG37
A	GLU63
A	ASP65
A	GLU171
A	LYS173
A	TYR313
A	MG1601
A	HOH1615
A	HOH1616
A	HOH1657
A	HOH1905

---

site_id	AC6
Number of Residues	11
Details	BINDING SITE FOR RESIDUE GOL B 1606

Chain	Residue
B	HIS36
B	ARG37
B	GLU63
B	ASP65
B	GLU171
B	LYS173
B	PHE210
B	MG1602
B	HOH1612
B	HOH1613
B	HOH1677

---

site_id	AC7
Number of Residues	10
Details	BINDING SITE FOR RESIDUE GOL C 1607

Chain	Residue
C	HIS36
C	ARG37
C	GLU63
C	GLU171
C	LYS173
C	PHE210
C	TYR313
C	MG1603
C	HOH1653
C	HOH1739

---

site_id	AC8
Number of Residues	11
Details	BINDING SITE FOR RESIDUE GOL D 1608

Chain	Residue
D	HIS36
D	ARG37
D	GLU63
D	ASP65
D	GLU171
D	LYS173
D	PHE210
D	MG1604
D	HOH1616
D	HOH1639
D	HOH1746

---

site_id	AC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL A 1609

Chain	Residue
A	LYS195
A	HOH1811
A	HOH1955
A	HOH1962

---

site_id	BC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE GOL B 1610

Chain	Residue
B	LYS195
B	HOH1847
B	HOH1870

---

site_id	BC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL C 1611

Chain	Residue
B	LYS140
C	LYS195
C	TYR196
C	HOH1750

---

site_id	BC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE GOL D 1612

Chain	Residue
D	LYS195
D	TYR196

---

site_id	BC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL C 1613

Chain	Residue
C	ARG95
C	ALA96
C	ASP106
C	HOH1862

---

site_id	BC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL A 1614

Chain	Residue
A	ARG95
A	ASP106
A	HOH1779
A	HOH1909
A	HOH1910

---

site_id	BC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL D 1615

Chain	Residue
D	ARG95
D	ARG97
D	ASP106
D	HOH1728
D	HOH1736

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	ACT_SITE: Proton acceptor => ECO:0000250|UniProtKB:Q8RB32

Chain	Residue	Details
A	HIS36
B	HIS36
C	HIS36
D	HIS36

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	ACT_SITE: Proton donor => ECO:0000250|UniProtKB:Q8RB32

Chain	Residue	Details
A	HIS78
B	HIS78
C	HIS78
D	HIS78

---

site_id	SWS_FT_FI3
Number of Residues	12
Details	BINDING: BINDING => ECO:0000269|Ref.9, ECO:0007744|PDB:1T8Q, ECO:0007744|PDB:1YDY

Chain	Residue	Details
A	GLU63
D	GLU63
D	ASP65
D	GLU171
A	ASP65
A	GLU171
B	GLU63
B	ASP65
B	GLU171
C	GLU63
C	ASP65
C	GLU171

---