1T61
crystal structure of collagen IV NC1 domain from placenta basement membrane
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005201 | molecular_function | extracellular matrix structural constituent |
| A | 0005581 | cellular_component | collagen trimer |
| B | 0005201 | molecular_function | extracellular matrix structural constituent |
| B | 0005581 | cellular_component | collagen trimer |
| C | 0005201 | molecular_function | extracellular matrix structural constituent |
| C | 0005581 | cellular_component | collagen trimer |
| C | 0005587 | cellular_component | collagen type IV trimer |
| C | 0005604 | cellular_component | basement membrane |
| C | 0030199 | biological_process | collagen fibril organization |
| D | 0005201 | molecular_function | extracellular matrix structural constituent |
| D | 0005581 | cellular_component | collagen trimer |
| E | 0005201 | molecular_function | extracellular matrix structural constituent |
| E | 0005581 | cellular_component | collagen trimer |
| F | 0005201 | molecular_function | extracellular matrix structural constituent |
| F | 0005581 | cellular_component | collagen trimer |
| F | 0005587 | cellular_component | collagen type IV trimer |
| F | 0005604 | cellular_component | basement membrane |
| F | 0030199 | biological_process | collagen fibril organization |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE K C 801 |
| Chain | Residue |
| A | TYR189 |
| C | TYR63 |
| C | ASN65 |
| E | ALA186 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE K A 802 |
| Chain | Residue |
| A | ALA186 |
| D | ASN66 |
| E | TYR189 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE K F 803 |
| Chain | Residue |
| F | TYR63 |
| F | ASN65 |
| B | ALA186 |
| D | TYR189 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE K C 805 |
| Chain | Residue |
| C | TYR183 |
| C | ALA184 |
| E | ASN66 |
| F | TYR187 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE K B 806 |
| Chain | Residue |
| B | ASN66 |
| C | TYR187 |
| F | ALA184 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE K A 807 |
| Chain | Residue |
| A | ASN66 |
| B | TYR189 |
| D | ALA186 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CL D 804 |
| Chain | Residue |
| A | HOH875 |
| D | ALA74 |
| D | ARG76 |
| D | ASP78 |
| D | GLY178 |
| D | HOH830 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE CL C 808 |
| Chain | Residue |
| C | ALA73 |
| C | SER74 |
| C | ARG75 |
| C | ASN76 |
| C | ASP77 |
| C | HOH832 |
| C | HOH834 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CL B 809 |
| Chain | Residue |
| B | ALA74 |
| B | ARG76 |
| B | ASP78 |
| B | GLY178 |
| B | ARG179 |
| B | HOH829 |
| site_id | BC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CL A 810 |
| Chain | Residue |
| A | ALA74 |
| A | ARG76 |
| A | ASN77 |
| A | ASP78 |
| A | HOH835 |
| D | HOH857 |
| site_id | BC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CL E 811 |
| Chain | Residue |
| C | ARG177 |
| E | ALA74 |
| E | ARG76 |
| E | ASP78 |
| E | GLY178 |
| E | HOH841 |
| site_id | BC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CL F 812 |
| Chain | Residue |
| F | ALA73 |
| F | ARG75 |
| F | ASN76 |
| F | ASP77 |
| F | HOH833 |
| F | HOH834 |
| site_id | BC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA F 813 |
| Chain | Residue |
| B | HOH883 |
| C | ASP148 |
| F | ASP148 |
| F | GLU149 |
| F | HOH908 |
| F | HOH914 |
| site_id | BC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CA C 814 |
| Chain | Residue |
| C | ASP148 |
| C | GLU149 |
| C | HOH923 |
| E | HOH890 |
| F | HOH914 |
| site_id | BC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 811 |
| Chain | Residue |
| A | TYR28 |
| A | CYS53 |
| A | ARG55 |
| B | VAL120 |
| B | HIS121 |
| B | HOH889 |
| site_id | BC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL E 812 |
| Chain | Residue |
| D | TYR28 |
| D | ARG55 |
| E | VAL120 |
| E | HIS121 |
| E | GLN123 |
| E | HOH887 |
| site_id | BC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL B 810 |
| Chain | Residue |
| A | LEU63 |
| A | PHE73 |
| B | ALA194 |
| B | THR195 |
| B | HIS218 |
| site_id | BC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL A 812 |
| Chain | Residue |
| A | GLU87 |
| A | PRO88 |
| A | MET89 |
| A | TYR184 |
| A | HOH831 |
| site_id | CC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A 813 |
| Chain | Residue |
| A | MET89 |
| A | TYR184 |
| A | TYR185 |
| A | ALA186 |
| A | HOH916 |
| C | PRO66 |
| D | ASN66 |
| site_id | CC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A 814 |
| Chain | Residue |
| A | HIS121 |
| A | GLN123 |
| A | HOH887 |
| C | TRP27 |
| C | LEU53 |
| C | ALA54 |
| A | VAL120 |
| site_id | CC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL D 805 |
| Chain | Residue |
| D | VAL120 |
| D | HIS121 |
| D | HOH845 |
| F | TRP27 |
| F | ALA54 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | Cross-link: {"description":"S-Lysyl-methionine sulfilimine (Met-Lys) (interchain with K-1651)","evidences":[{"source":"PubMed","id":"19729652","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | Cross-link: {"description":"S-Lysyl-methionine sulfilimine (Lys-Met) (interchain with M-1533)","evidences":[{"source":"PubMed","id":"19729652","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
