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1T5O

Crystal structure of the translation initiation factor eIF-2B, subunit delta, from A. fulgidus

Functional Information from GO Data
ChainGOidnamespacecontents
A0008652biological_processamino acid biosynthetic process
A0009086biological_processmethionine biosynthetic process
A0016853molecular_functionisomerase activity
A0019509biological_processL-methionine salvage from methylthioadenosine
A0046523molecular_functionS-methyl-5-thioribose-1-phosphate isomerase activity
B0008652biological_processamino acid biosynthetic process
B0009086biological_processmethionine biosynthetic process
B0016853molecular_functionisomerase activity
B0019509biological_processL-methionine salvage from methylthioadenosine
B0046523molecular_functionS-methyl-5-thioribose-1-phosphate isomerase activity
C0008652biological_processamino acid biosynthetic process
C0009086biological_processmethionine biosynthetic process
C0016853molecular_functionisomerase activity
C0019509biological_processL-methionine salvage from methylthioadenosine
C0046523molecular_functionS-methyl-5-thioribose-1-phosphate isomerase activity
D0008652biological_processamino acid biosynthetic process
D0009086biological_processmethionine biosynthetic process
D0016853molecular_functionisomerase activity
D0019509biological_processL-methionine salvage from methylthioadenosine
D0046523molecular_functionS-methyl-5-thioribose-1-phosphate isomerase activity
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues4
DetailsACT_SITE: Proton donor => ECO:0000255|HAMAP-Rule:MF_01678
ChainResidueDetails
AASP234
BASP234
CASP234
DASP234

site_idSWS_FT_FI2
Number of Residues16
DetailsBINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_01678
ChainResidueDetails
AARG45
CARG88
CGLN193
CASN243
DARG45
DARG88
DGLN193
DASN243
AARG88
AGLN193
AASN243
BARG45
BARG88
BGLN193
BASN243
CARG45

site_idSWS_FT_FI3
Number of Residues4
DetailsSITE: Transition state stabilizer => ECO:0000255|HAMAP-Rule:MF_01678
ChainResidueDetails
ACYS154
BCYS154
CCYS154
DCYS154

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PDB entries from 2025-06-11

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