Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

1T5E

The structure of MexA

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005886	cellular_component	plasma membrane
A	0009636	biological_process	response to toxic substance
A	0015297	molecular_function	antiporter activity
A	0015562	molecular_function	efflux transmembrane transporter activity
A	0016020	cellular_component	membrane
A	0022857	molecular_function	transmembrane transporter activity
A	0042802	molecular_function	identical protein binding
A	0042908	biological_process	xenobiotic transport
A	0046677	biological_process	response to antibiotic
A	0051260	biological_process	protein homooligomerization
A	0055085	biological_process	transmembrane transport
B	0005886	cellular_component	plasma membrane
B	0009636	biological_process	response to toxic substance
B	0015297	molecular_function	antiporter activity
B	0015562	molecular_function	efflux transmembrane transporter activity
B	0016020	cellular_component	membrane
B	0022857	molecular_function	transmembrane transporter activity
B	0042802	molecular_function	identical protein binding
B	0042908	biological_process	xenobiotic transport
B	0046677	biological_process	response to antibiotic
B	0051260	biological_process	protein homooligomerization
B	0055085	biological_process	transmembrane transport
C	0005886	cellular_component	plasma membrane
C	0009636	biological_process	response to toxic substance
C	0015297	molecular_function	antiporter activity
C	0015562	molecular_function	efflux transmembrane transporter activity
C	0016020	cellular_component	membrane
C	0022857	molecular_function	transmembrane transporter activity
C	0042802	molecular_function	identical protein binding
C	0042908	biological_process	xenobiotic transport
C	0046677	biological_process	response to antibiotic
C	0051260	biological_process	protein homooligomerization
C	0055085	biological_process	transmembrane transport
D	0005886	cellular_component	plasma membrane
D	0009636	biological_process	response to toxic substance
D	0015297	molecular_function	antiporter activity
D	0015562	molecular_function	efflux transmembrane transporter activity
D	0016020	cellular_component	membrane
D	0022857	molecular_function	transmembrane transporter activity
D	0042802	molecular_function	identical protein binding
D	0042908	biological_process	xenobiotic transport
D	0046677	biological_process	response to antibiotic
D	0051260	biological_process	protein homooligomerization
D	0055085	biological_process	transmembrane transport
E	0005886	cellular_component	plasma membrane
E	0009636	biological_process	response to toxic substance
E	0015297	molecular_function	antiporter activity
E	0015562	molecular_function	efflux transmembrane transporter activity
E	0016020	cellular_component	membrane
E	0022857	molecular_function	transmembrane transporter activity
E	0042802	molecular_function	identical protein binding
E	0042908	biological_process	xenobiotic transport
E	0046677	biological_process	response to antibiotic
E	0051260	biological_process	protein homooligomerization
E	0055085	biological_process	transmembrane transport
F	0005886	cellular_component	plasma membrane
F	0009636	biological_process	response to toxic substance
F	0015297	molecular_function	antiporter activity
F	0015562	molecular_function	efflux transmembrane transporter activity
F	0016020	cellular_component	membrane
F	0022857	molecular_function	transmembrane transporter activity
F	0042802	molecular_function	identical protein binding
F	0042908	biological_process	xenobiotic transport
F	0046677	biological_process	response to antibiotic
F	0051260	biological_process	protein homooligomerization
F	0055085	biological_process	transmembrane transport
G	0005886	cellular_component	plasma membrane
G	0009636	biological_process	response to toxic substance
G	0015297	molecular_function	antiporter activity
G	0015562	molecular_function	efflux transmembrane transporter activity
G	0016020	cellular_component	membrane
G	0022857	molecular_function	transmembrane transporter activity
G	0042802	molecular_function	identical protein binding
G	0042908	biological_process	xenobiotic transport
G	0046677	biological_process	response to antibiotic
G	0051260	biological_process	protein homooligomerization
G	0055085	biological_process	transmembrane transport
H	0005886	cellular_component	plasma membrane
H	0009636	biological_process	response to toxic substance
H	0015297	molecular_function	antiporter activity
H	0015562	molecular_function	efflux transmembrane transporter activity
H	0016020	cellular_component	membrane
H	0022857	molecular_function	transmembrane transporter activity
H	0042802	molecular_function	identical protein binding
H	0042908	biological_process	xenobiotic transport
H	0046677	biological_process	response to antibiotic
H	0051260	biological_process	protein homooligomerization
H	0055085	biological_process	transmembrane transport
I	0005886	cellular_component	plasma membrane
I	0009636	biological_process	response to toxic substance
I	0015297	molecular_function	antiporter activity
I	0015562	molecular_function	efflux transmembrane transporter activity
I	0016020	cellular_component	membrane
I	0022857	molecular_function	transmembrane transporter activity
I	0042802	molecular_function	identical protein binding
I	0042908	biological_process	xenobiotic transport
I	0046677	biological_process	response to antibiotic
I	0051260	biological_process	protein homooligomerization
I	0055085	biological_process	transmembrane transport
J	0005886	cellular_component	plasma membrane
J	0009636	biological_process	response to toxic substance
J	0015297	molecular_function	antiporter activity
J	0015562	molecular_function	efflux transmembrane transporter activity
J	0016020	cellular_component	membrane
J	0022857	molecular_function	transmembrane transporter activity
J	0042802	molecular_function	identical protein binding
J	0042908	biological_process	xenobiotic transport
J	0046677	biological_process	response to antibiotic
J	0051260	biological_process	protein homooligomerization
J	0055085	biological_process	transmembrane transport
K	0005886	cellular_component	plasma membrane
K	0009636	biological_process	response to toxic substance
K	0015297	molecular_function	antiporter activity
K	0015562	molecular_function	efflux transmembrane transporter activity
K	0016020	cellular_component	membrane
K	0022857	molecular_function	transmembrane transporter activity
K	0042802	molecular_function	identical protein binding
K	0042908	biological_process	xenobiotic transport
K	0046677	biological_process	response to antibiotic
K	0051260	biological_process	protein homooligomerization
K	0055085	biological_process	transmembrane transport
L	0005886	cellular_component	plasma membrane
L	0009636	biological_process	response to toxic substance
L	0015297	molecular_function	antiporter activity
L	0015562	molecular_function	efflux transmembrane transporter activity
L	0016020	cellular_component	membrane
L	0022857	molecular_function	transmembrane transporter activity
L	0042802	molecular_function	identical protein binding
L	0042908	biological_process	xenobiotic transport
L	0046677	biological_process	response to antibiotic
L	0051260	biological_process	protein homooligomerization
L	0055085	biological_process	transmembrane transport
M	0005886	cellular_component	plasma membrane
M	0009636	biological_process	response to toxic substance
M	0015297	molecular_function	antiporter activity
M	0015562	molecular_function	efflux transmembrane transporter activity
M	0016020	cellular_component	membrane
M	0022857	molecular_function	transmembrane transporter activity
M	0042802	molecular_function	identical protein binding
M	0042908	biological_process	xenobiotic transport
M	0046677	biological_process	response to antibiotic
M	0051260	biological_process	protein homooligomerization
M	0055085	biological_process	transmembrane transport

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE 3GR C 361

Chain	Residue
C	GLY146
C	ARG147
D	VAL227
D	SER228

site_id	AC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE 3GR D 361

Chain	Residue
D	GLY146
D	ARG147
D	THR166

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE 3GR E 361

Chain	Residue
F	VAL227
F	SER228
E	GLY146
E	ARG147

site_id	AC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE 3GR F 361

Chain	Residue
F	GLY146
F	ARG147

site_id	AC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE 3GR G 361

Chain	Residue
G	GLY146
G	ARG147
G	THR166

site_id	AC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE 3GR H 361

Chain	Residue
G	VAL227
G	SER228
H	GLY146
H	ARG147

site_id	AC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE 3GR I 361

Chain	Residue
H	VAL227
H	SER228
I	GLY146
I	ARG147

site_id	AC8
Number of Residues	2
Details	BINDING SITE FOR RESIDUE 3GR K 361

Chain	Residue
K	GLY146
K	ARG147

site_id	AC9
Number of Residues	3
Details	BINDING SITE FOR RESIDUE 3GR L 361

Chain	Residue
K	VAL227
L	GLY146
L	ARG147

site_id	BC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE GOL A 361

Chain	Residue
A	ARG147
B	VAL227
B	SER228

site_id	BC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE GOL B 361

Chain	Residue
B	GLY146
B	ARG147

site_id	BC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL J 361

Chain	Residue
I	VAL227
I	SER228
J	GLY146
J	ARG147

site_id	BC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL M 361

Chain	Residue
L	VAL227
L	SER228
M	GLY146
M	ARG147

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	13
Details	LIPID: S-diacylglycerol cysteine => ECO:0000305\|PubMed:10671490

Chain	Residue	Details
A	CYS1
J	CYS1
K	CYS1
L	CYS1
M	CYS1
B	CYS1
C	CYS1
D	CYS1
E	CYS1
F	CYS1
G	CYS1
H	CYS1
I	CYS1

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)