1T4E
Structure of Human MDM2 in complex with a Benzodiazepine Inhibitor
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005634 | cellular_component | nucleus |
| A | 0043066 | biological_process | negative regulation of apoptotic process |
| A | 0051726 | biological_process | regulation of cell cycle |
| B | 0005634 | cellular_component | nucleus |
| B | 0043066 | biological_process | negative regulation of apoptotic process |
| B | 0051726 | biological_process | regulation of cell cycle |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE DIZ A 112 |
| Chain | Residue |
| A | GLY16 |
| A | HIS96 |
| A | ILE99 |
| A | TYR100 |
| A | HOH114 |
| A | HOH125 |
| B | LYS51 |
| A | SER17 |
| A | LEU54 |
| A | LEU57 |
| A | GLY58 |
| A | ILE61 |
| A | MET62 |
| A | GLN72 |
| A | VAL93 |
| site_id | AC2 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE DIZ B 112 |
| Chain | Residue |
| B | GLY16 |
| B | SER17 |
| B | LEU54 |
| B | LEU57 |
| B | GLY58 |
| B | ILE61 |
| B | MET62 |
| B | GLN72 |
| B | VAL93 |
| B | HIS96 |
| B | TYR100 |
| B | HOH128 |
| B | HOH134 |
