1SR4

Crystal Structure of the Haemophilus ducreyi cytolethal distending toxin

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0009279	cellular_component	cell outer membrane
A	0030246	molecular_function	carbohydrate binding
A	0035821	biological_process	modulation of process of another organism
A	0090729	molecular_function	toxin activity
B	0003824	molecular_function	catalytic activity
C	0009279	cellular_component	cell outer membrane
C	0030246	molecular_function	carbohydrate binding
C	0035821	biological_process	modulation of process of another organism
C	0090729	molecular_function	toxin activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE BR B 501

Chain	Residue
B	HIS135
B	SER136
B	SER143
B	ARG144
B	PRO145

---

site_id	AC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE BR B 502

Chain	Residue
B	SER139
B	VAL140

---

site_id	AC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE BR A 503

Chain	Residue
A	ASN112
A	HOH613

---

site_id	AC4
Number of Residues	1
Details	BINDING SITE FOR RESIDUE BR B 504

Chain	Residue
B	GLN127

---

site_id	AC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE BR A 505

Chain	Residue
A	TRP100
A	HOH541
A	HOH585

---

site_id	AC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE BR C 506

Chain	Residue
C	LYS89
C	GLY92
C	ALA93

---

site_id	AC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE BR A 507

Chain	Residue
A	PRO74
A	GLN132
A	HOH620

---

site_id	AC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE BR A 508

Chain	Residue
A	SER72
A	ASN76
B	GLU56

---

site_id	AC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE BR A 510

Chain	Residue
A	LEU93
A	HOH611

---

site_id	BC1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE BR A 511

Chain	Residue
A	LYS95

---

site_id	BC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE BR B 512

Chain	Residue
B	THR92
B	MET103

---

site_id	BC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE BR B 513

Chain	Residue
B	BR522

---

site_id	BC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE BR C 514

Chain	Residue
A	SER63
A	HOH662
C	HOH639

---

site_id	BC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE BR A 515

Chain	Residue
A	TYR141

---

site_id	BC6
Number of Residues	1
Details	BINDING SITE FOR RESIDUE BR C 516

Chain	Residue
C	ALA94

---

site_id	BC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE BR A 517

Chain	Residue
A	ARG67
A	LEU70

---

site_id	BC8
Number of Residues	1
Details	BINDING SITE FOR RESIDUE BR A 518

Chain	Residue
A	ASN58

---

site_id	BC9
Number of Residues	1
Details	BINDING SITE FOR RESIDUE BR B 519

Chain	Residue
B	ARG250

---

site_id	CC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE BR B 520

Chain	Residue
A	PHE189
A	HOH557
B	SER99

---

site_id	CC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE BR B 521

Chain	Residue
B	PRO204
B	ALA205
B	HOH621

---

site_id	CC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE BR B 522

Chain	Residue
B	VAL280
B	ARG281
B	BR513

---

site_id	CC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE BR B 523

Chain	Residue
B	HIS160
B	ASN201

---

site_id	CC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE BR C 524

Chain	Residue
C	GLY150

---

site_id	CC6
Number of Residues	1
Details	BINDING SITE FOR RESIDUE BR A 525

Chain	Residue
A	ARG124

---

site_id	CC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE BR C 526

Chain	Residue
A	ASP199
C	LYS174
C	ILE175

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	89
Details	Domain: {"description":"Ricin B-type lectin","evidences":[{"source":"PROSITE-ProRule","id":"PRU00174","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	11
Details	Region: {"description":"Mediates binding to target cells","evidences":[{"evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---