1SQD

Structural basis for inhibitor selectivity revealed by crystal structures of plant and mammalian 4-hydroxyphenylpyruvate dioxygenases

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003868	molecular_function	4-hydroxyphenylpyruvate dioxygenase activity
A	0005506	molecular_function	iron ion binding
A	0005737	cellular_component	cytoplasm
A	0006559	biological_process	L-phenylalanine catabolic process
A	0006572	biological_process	tyrosine catabolic process
A	0009072	biological_process	aromatic amino acid metabolic process
A	0016701	molecular_function	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen
A	0042802	molecular_function	identical protein binding
A	0046872	molecular_function	metal ion binding
A	0051213	molecular_function	dioxygenase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE FE A 500

Chain	Residue
A	HIS205
A	HIS287
A	GLU373
A	HOH1001
A	HOH1011
A	HOH1012

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3
Details	BINDING: BINDING => ECO:0000269|PubMed:15301540

Chain	Residue	Details
A	HIS205
A	HIS287
A	GLU373

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