1SOR
Aquaporin-0 membrane junctions reveal the structure of a closed water pore
Functional Information from GO Data
Functional Information from PROSITE/UniProt
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 17 |
| Details | TRANSMEM: Helical; Name=1 => ECO:0000269|PubMed:16319884, ECO:0007744|PDB:2B6O |
| Chain | Residue | Details |
| A | ILE13-ALA30 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 35 |
| Details | TOPO_DOM: Extracellular => ECO:0000269|PubMed:16319884 |
| Chain | Residue | Details |
| A | SER31-HIS40 | |
| A | VAL107-SER126 | |
| A | MET176-TYR177 | |
| A | LEU194-ASN200 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 18 |
| Details | TRANSMEM: Helical; Name=2 => ECO:0000269|PubMed:16319884, ECO:0007744|PDB:2B6O |
| Chain | Residue | Details |
| A | VAL41-VAL59 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 20 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000269|PubMed:16319884 |
| Chain | Residue | Details |
| A | GLY60-SER63 | |
| A | VAL77-ARG85 | |
| A | THR148-LEU157 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 27 |
| Details | INTRAMEM: Discontinuously helical => ECO:0000269|PubMed:16319884, ECO:0007744|PDB:2B6O |
| Chain | Residue | Details |
| A | GLY64-LEU76 | |
| A | TYR178-ILE193 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 20 |
| Details | TRANSMEM: Helical; Name=3 => ECO:0000269|PubMed:16319884, ECO:0007744|PDB:2B6O |
| Chain | Residue | Details |
| A | ALA86-SER106 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 20 |
| Details | TRANSMEM: Helical; Name=4 => ECO:0000269|PubMed:16319884, ECO:0007744|PDB:2B6O |
| Chain | Residue | Details |
| A | VAL127-ALA147 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 17 |
| Details | TRANSMEM: Helical; Name=5 => ECO:0000269|PubMed:16319884, ECO:0007744|PDB:2B6O |
| Chain | Residue | Details |
| A | GLY158-GLY175 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 17 |
| Details | TRANSMEM: Helical; Name=6 => ECO:0000269|PubMed:16319884, ECO:0007744|PDB:2B6O |
| Chain | Residue | Details |
| A | HIS201-LEU218 |
| site_id | SWS_FT_FI10 |
| Number of Residues | 1 |
| Details | SITE: Important for water channel gating => ECO:0000250|UniProtKB:P06624 |
| Chain | Residue | Details |
| A | TYR149 |
| site_id | SWS_FT_FI11 |
| Number of Residues | 1 |
| Details | SITE: Cleavage; promotes interactions between tetramers from adjoining membranes => ECO:0000269|PubMed:15351655 |
| Chain | Residue | Details |
| A | LEU234 |
| site_id | SWS_FT_FI12 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P06624 |
| Chain | Residue | Details |
| A | SER235 |
