1SAZ

Membership in the ASKHA Superfamily: Enzymological Properties and Crystal Structure of Butyrate Kinase 2 from Thermotoga maritima

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0006083	biological_process	acetate metabolic process
A	0008776	molecular_function	acetate kinase activity
A	0016301	molecular_function	kinase activity
A	0016310	biological_process	phosphorylation
A	0016740	molecular_function	transferase activity
A	0016774	molecular_function	phosphotransferase activity, carboxyl group as acceptor
A	0047761	molecular_function	butyrate kinase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE NA A 390

Chain	Residue
A	SER142
A	SER215
A	GLY216
A	THR217

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site_id	AC2
Number of Residues	15
Details	BINDING SITE FOR RESIDUE ACP A 399

Chain	Residue
A	GLY186
A	ARG214
A	SER254
A	ASP255
A	ALA256
A	ARG257
A	GLY304
A	LEU305
A	HIS307
A	HOH436
A	GLU22
A	HIS154
A	HIS182
A	GLY184
A	GLY185

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site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE FMT A 401

Chain	Residue
A	ARG74
A	ASP128
A	LEU156
A	GLU334

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site_id	AC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE FMT A 402

Chain	Residue
A	PHE2
A	ARG257

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site_id	AC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE FMT A 403

Chain	Residue
A	ASN177
A	LYS194

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site_id	AC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE FMT A 404

Chain	Residue
A	ARG275
A	TRP315
A	ARG319

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Functional Information from PROSITE/UniProt

site_id	PS01075
Number of Residues	12
Details	ACETATE_KINASE_1 Acetate and butyrate kinases family signature 1. ILtINpGSTStK

Chain	Residue	Details
A	ILE4-LYS15

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site_id	PS01076
Number of Residues	18
Details	ACETATE_KINASE_2 Acetate and butyrate kinases family signature 2. LVvaHmGgGiSIaAhrkG

Chain	Residue	Details
A	LEU178-GLY195

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