1S1E
Crystal Structure of Kv Channel-interacting protein 1 (KChIP-1)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005267 | molecular_function | potassium channel activity |
| A | 0005509 | molecular_function | calcium ion binding |
| A | 0005515 | molecular_function | protein binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0006811 | biological_process | monoatomic ion transport |
| A | 0006813 | biological_process | potassium ion transport |
| A | 0006936 | biological_process | muscle contraction |
| A | 0007268 | biological_process | chemical synaptic transmission |
| A | 0008016 | biological_process | regulation of heart contraction |
| A | 0008076 | cellular_component | voltage-gated potassium channel complex |
| A | 0009898 | cellular_component | cytoplasmic side of plasma membrane |
| A | 0009966 | biological_process | regulation of signal transduction |
| A | 0015459 | molecular_function | potassium channel regulator activity |
| A | 0016020 | cellular_component | membrane |
| A | 0030425 | cellular_component | dendrite |
| A | 0034220 | biological_process | monoatomic ion transmembrane transport |
| A | 0034702 | cellular_component | monoatomic ion channel complex |
| A | 0042995 | cellular_component | cell projection |
| A | 0044325 | molecular_function | transmembrane transporter binding |
| A | 0045202 | cellular_component | synapse |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0071196 | cellular_component | Kv4.3-KChIP1 channel complex |
| A | 0071805 | biological_process | potassium ion transmembrane transport |
| A | 0086009 | biological_process | membrane repolarization |
| A | 0097623 | biological_process | potassium ion export across plasma membrane |
| A | 1901379 | biological_process | regulation of potassium ion transmembrane transport |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 225 |
| Chain | Residue |
| A | ASP135 |
| A | ASN137 |
| A | ASP139 |
| A | TYR141 |
| A | GLU146 |
| A | HOH239 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 226 |
| Chain | Residue |
| A | ILE189 |
| A | GLU194 |
| A | HOH264 |
| A | ASP183 |
| A | ASN185 |
| A | ASP187 |
Functional Information from PROSITE/UniProt
| site_id | PS00018 |
| Number of Residues | 13 |
| Details | EF_HAND_1 EF-hand calcium-binding domain. DINKDGYINkeEM |
| Chain | Residue | Details |
| A | ASP135-MET147 | |
| A | ASP183-PHE195 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 35 |
| Details | Domain: {"description":"EF-hand 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 35 |
| Details | Domain: {"description":"EF-hand 3","evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 35 |
| Details | Domain: {"description":"EF-hand 4","evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 13 |
| Details | Region: {"description":"Interaction with KCND2","evidences":[{"source":"UniProtKB","id":"Q8R426","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 9 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"17057713","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17187064","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
