1RXU
E. coli uridine phosphorylase: thymidine phosphate complex
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0003824 | molecular_function | catalytic activity |
A | 0004850 | molecular_function | uridine phosphorylase activity |
A | 0005524 | molecular_function | ATP binding |
A | 0005737 | cellular_component | cytoplasm |
A | 0005829 | cellular_component | cytosol |
A | 0006218 | biological_process | uridine catabolic process |
A | 0006974 | biological_process | DNA damage response |
A | 0009116 | biological_process | nucleoside metabolic process |
A | 0009164 | biological_process | nucleoside catabolic process |
A | 0009166 | biological_process | nucleotide catabolic process |
A | 0016757 | molecular_function | glycosyltransferase activity |
A | 0016763 | molecular_function | pentosyltransferase activity |
A | 0030955 | molecular_function | potassium ion binding |
A | 0032991 | cellular_component | protein-containing complex |
A | 0042802 | molecular_function | identical protein binding |
A | 0044206 | biological_process | UMP salvage |
A | 0046050 | biological_process | UMP catabolic process |
A | 0047847 | molecular_function | deoxyuridine phosphorylase activity |
B | 0003824 | molecular_function | catalytic activity |
B | 0004850 | molecular_function | uridine phosphorylase activity |
B | 0005524 | molecular_function | ATP binding |
B | 0005737 | cellular_component | cytoplasm |
B | 0005829 | cellular_component | cytosol |
B | 0006218 | biological_process | uridine catabolic process |
B | 0006974 | biological_process | DNA damage response |
B | 0009116 | biological_process | nucleoside metabolic process |
B | 0009164 | biological_process | nucleoside catabolic process |
B | 0009166 | biological_process | nucleotide catabolic process |
B | 0016757 | molecular_function | glycosyltransferase activity |
B | 0016763 | molecular_function | pentosyltransferase activity |
B | 0030955 | molecular_function | potassium ion binding |
B | 0032991 | cellular_component | protein-containing complex |
B | 0042802 | molecular_function | identical protein binding |
B | 0044206 | biological_process | UMP salvage |
B | 0046050 | biological_process | UMP catabolic process |
B | 0047847 | molecular_function | deoxyuridine phosphorylase activity |
C | 0003824 | molecular_function | catalytic activity |
C | 0004850 | molecular_function | uridine phosphorylase activity |
C | 0005524 | molecular_function | ATP binding |
C | 0005737 | cellular_component | cytoplasm |
C | 0005829 | cellular_component | cytosol |
C | 0006218 | biological_process | uridine catabolic process |
C | 0006974 | biological_process | DNA damage response |
C | 0009116 | biological_process | nucleoside metabolic process |
C | 0009164 | biological_process | nucleoside catabolic process |
C | 0009166 | biological_process | nucleotide catabolic process |
C | 0016757 | molecular_function | glycosyltransferase activity |
C | 0016763 | molecular_function | pentosyltransferase activity |
C | 0030955 | molecular_function | potassium ion binding |
C | 0032991 | cellular_component | protein-containing complex |
C | 0042802 | molecular_function | identical protein binding |
C | 0044206 | biological_process | UMP salvage |
C | 0046050 | biological_process | UMP catabolic process |
C | 0047847 | molecular_function | deoxyuridine phosphorylase activity |
D | 0003824 | molecular_function | catalytic activity |
D | 0004850 | molecular_function | uridine phosphorylase activity |
D | 0005524 | molecular_function | ATP binding |
D | 0005737 | cellular_component | cytoplasm |
D | 0005829 | cellular_component | cytosol |
D | 0006218 | biological_process | uridine catabolic process |
D | 0006974 | biological_process | DNA damage response |
D | 0009116 | biological_process | nucleoside metabolic process |
D | 0009164 | biological_process | nucleoside catabolic process |
D | 0009166 | biological_process | nucleotide catabolic process |
D | 0016757 | molecular_function | glycosyltransferase activity |
D | 0016763 | molecular_function | pentosyltransferase activity |
D | 0030955 | molecular_function | potassium ion binding |
D | 0032991 | cellular_component | protein-containing complex |
D | 0042802 | molecular_function | identical protein binding |
D | 0044206 | biological_process | UMP salvage |
D | 0046050 | biological_process | UMP catabolic process |
D | 0047847 | molecular_function | deoxyuridine phosphorylase activity |
E | 0003824 | molecular_function | catalytic activity |
E | 0004850 | molecular_function | uridine phosphorylase activity |
E | 0005524 | molecular_function | ATP binding |
E | 0005737 | cellular_component | cytoplasm |
E | 0005829 | cellular_component | cytosol |
E | 0006218 | biological_process | uridine catabolic process |
E | 0006974 | biological_process | DNA damage response |
E | 0009116 | biological_process | nucleoside metabolic process |
E | 0009164 | biological_process | nucleoside catabolic process |
E | 0009166 | biological_process | nucleotide catabolic process |
E | 0016757 | molecular_function | glycosyltransferase activity |
E | 0016763 | molecular_function | pentosyltransferase activity |
E | 0030955 | molecular_function | potassium ion binding |
E | 0032991 | cellular_component | protein-containing complex |
E | 0042802 | molecular_function | identical protein binding |
E | 0044206 | biological_process | UMP salvage |
E | 0046050 | biological_process | UMP catabolic process |
E | 0047847 | molecular_function | deoxyuridine phosphorylase activity |
F | 0003824 | molecular_function | catalytic activity |
F | 0004850 | molecular_function | uridine phosphorylase activity |
F | 0005524 | molecular_function | ATP binding |
F | 0005737 | cellular_component | cytoplasm |
F | 0005829 | cellular_component | cytosol |
F | 0006218 | biological_process | uridine catabolic process |
F | 0006974 | biological_process | DNA damage response |
F | 0009116 | biological_process | nucleoside metabolic process |
F | 0009164 | biological_process | nucleoside catabolic process |
F | 0009166 | biological_process | nucleotide catabolic process |
F | 0016757 | molecular_function | glycosyltransferase activity |
F | 0016763 | molecular_function | pentosyltransferase activity |
F | 0030955 | molecular_function | potassium ion binding |
F | 0032991 | cellular_component | protein-containing complex |
F | 0042802 | molecular_function | identical protein binding |
F | 0044206 | biological_process | UMP salvage |
F | 0046050 | biological_process | UMP catabolic process |
F | 0047847 | molecular_function | deoxyuridine phosphorylase activity |
G | 0003824 | molecular_function | catalytic activity |
G | 0004850 | molecular_function | uridine phosphorylase activity |
G | 0005524 | molecular_function | ATP binding |
G | 0005737 | cellular_component | cytoplasm |
G | 0005829 | cellular_component | cytosol |
G | 0006218 | biological_process | uridine catabolic process |
G | 0006974 | biological_process | DNA damage response |
G | 0009116 | biological_process | nucleoside metabolic process |
G | 0009164 | biological_process | nucleoside catabolic process |
G | 0009166 | biological_process | nucleotide catabolic process |
G | 0016757 | molecular_function | glycosyltransferase activity |
G | 0016763 | molecular_function | pentosyltransferase activity |
G | 0030955 | molecular_function | potassium ion binding |
G | 0032991 | cellular_component | protein-containing complex |
G | 0042802 | molecular_function | identical protein binding |
G | 0044206 | biological_process | UMP salvage |
G | 0046050 | biological_process | UMP catabolic process |
G | 0047847 | molecular_function | deoxyuridine phosphorylase activity |
H | 0003824 | molecular_function | catalytic activity |
H | 0004850 | molecular_function | uridine phosphorylase activity |
H | 0005524 | molecular_function | ATP binding |
H | 0005737 | cellular_component | cytoplasm |
H | 0005829 | cellular_component | cytosol |
H | 0006218 | biological_process | uridine catabolic process |
H | 0006974 | biological_process | DNA damage response |
H | 0009116 | biological_process | nucleoside metabolic process |
H | 0009164 | biological_process | nucleoside catabolic process |
H | 0009166 | biological_process | nucleotide catabolic process |
H | 0016757 | molecular_function | glycosyltransferase activity |
H | 0016763 | molecular_function | pentosyltransferase activity |
H | 0030955 | molecular_function | potassium ion binding |
H | 0032991 | cellular_component | protein-containing complex |
H | 0042802 | molecular_function | identical protein binding |
H | 0044206 | biological_process | UMP salvage |
H | 0046050 | biological_process | UMP catabolic process |
H | 0047847 | molecular_function | deoxyuridine phosphorylase activity |
I | 0003824 | molecular_function | catalytic activity |
I | 0004850 | molecular_function | uridine phosphorylase activity |
I | 0005524 | molecular_function | ATP binding |
I | 0005737 | cellular_component | cytoplasm |
I | 0005829 | cellular_component | cytosol |
I | 0006218 | biological_process | uridine catabolic process |
I | 0006974 | biological_process | DNA damage response |
I | 0009116 | biological_process | nucleoside metabolic process |
I | 0009164 | biological_process | nucleoside catabolic process |
I | 0009166 | biological_process | nucleotide catabolic process |
I | 0016757 | molecular_function | glycosyltransferase activity |
I | 0016763 | molecular_function | pentosyltransferase activity |
I | 0030955 | molecular_function | potassium ion binding |
I | 0032991 | cellular_component | protein-containing complex |
I | 0042802 | molecular_function | identical protein binding |
I | 0044206 | biological_process | UMP salvage |
I | 0046050 | biological_process | UMP catabolic process |
I | 0047847 | molecular_function | deoxyuridine phosphorylase activity |
J | 0003824 | molecular_function | catalytic activity |
J | 0004850 | molecular_function | uridine phosphorylase activity |
J | 0005524 | molecular_function | ATP binding |
J | 0005737 | cellular_component | cytoplasm |
J | 0005829 | cellular_component | cytosol |
J | 0006218 | biological_process | uridine catabolic process |
J | 0006974 | biological_process | DNA damage response |
J | 0009116 | biological_process | nucleoside metabolic process |
J | 0009164 | biological_process | nucleoside catabolic process |
J | 0009166 | biological_process | nucleotide catabolic process |
J | 0016757 | molecular_function | glycosyltransferase activity |
J | 0016763 | molecular_function | pentosyltransferase activity |
J | 0030955 | molecular_function | potassium ion binding |
J | 0032991 | cellular_component | protein-containing complex |
J | 0042802 | molecular_function | identical protein binding |
J | 0044206 | biological_process | UMP salvage |
J | 0046050 | biological_process | UMP catabolic process |
J | 0047847 | molecular_function | deoxyuridine phosphorylase activity |
K | 0003824 | molecular_function | catalytic activity |
K | 0004850 | molecular_function | uridine phosphorylase activity |
K | 0005524 | molecular_function | ATP binding |
K | 0005737 | cellular_component | cytoplasm |
K | 0005829 | cellular_component | cytosol |
K | 0006218 | biological_process | uridine catabolic process |
K | 0006974 | biological_process | DNA damage response |
K | 0009116 | biological_process | nucleoside metabolic process |
K | 0009164 | biological_process | nucleoside catabolic process |
K | 0009166 | biological_process | nucleotide catabolic process |
K | 0016757 | molecular_function | glycosyltransferase activity |
K | 0016763 | molecular_function | pentosyltransferase activity |
K | 0030955 | molecular_function | potassium ion binding |
K | 0032991 | cellular_component | protein-containing complex |
K | 0042802 | molecular_function | identical protein binding |
K | 0044206 | biological_process | UMP salvage |
K | 0046050 | biological_process | UMP catabolic process |
K | 0047847 | molecular_function | deoxyuridine phosphorylase activity |
L | 0003824 | molecular_function | catalytic activity |
L | 0004850 | molecular_function | uridine phosphorylase activity |
L | 0005524 | molecular_function | ATP binding |
L | 0005737 | cellular_component | cytoplasm |
L | 0005829 | cellular_component | cytosol |
L | 0006218 | biological_process | uridine catabolic process |
L | 0006974 | biological_process | DNA damage response |
L | 0009116 | biological_process | nucleoside metabolic process |
L | 0009164 | biological_process | nucleoside catabolic process |
L | 0009166 | biological_process | nucleotide catabolic process |
L | 0016757 | molecular_function | glycosyltransferase activity |
L | 0016763 | molecular_function | pentosyltransferase activity |
L | 0030955 | molecular_function | potassium ion binding |
L | 0032991 | cellular_component | protein-containing complex |
L | 0042802 | molecular_function | identical protein binding |
L | 0044206 | biological_process | UMP salvage |
L | 0046050 | biological_process | UMP catabolic process |
L | 0047847 | molecular_function | deoxyuridine phosphorylase activity |
M | 0003824 | molecular_function | catalytic activity |
M | 0004850 | molecular_function | uridine phosphorylase activity |
M | 0005524 | molecular_function | ATP binding |
M | 0005737 | cellular_component | cytoplasm |
M | 0005829 | cellular_component | cytosol |
M | 0006218 | biological_process | uridine catabolic process |
M | 0006974 | biological_process | DNA damage response |
M | 0009116 | biological_process | nucleoside metabolic process |
M | 0009164 | biological_process | nucleoside catabolic process |
M | 0009166 | biological_process | nucleotide catabolic process |
M | 0016757 | molecular_function | glycosyltransferase activity |
M | 0016763 | molecular_function | pentosyltransferase activity |
M | 0030955 | molecular_function | potassium ion binding |
M | 0032991 | cellular_component | protein-containing complex |
M | 0042802 | molecular_function | identical protein binding |
M | 0044206 | biological_process | UMP salvage |
M | 0046050 | biological_process | UMP catabolic process |
M | 0047847 | molecular_function | deoxyuridine phosphorylase activity |
N | 0003824 | molecular_function | catalytic activity |
N | 0004850 | molecular_function | uridine phosphorylase activity |
N | 0005524 | molecular_function | ATP binding |
N | 0005737 | cellular_component | cytoplasm |
N | 0005829 | cellular_component | cytosol |
N | 0006218 | biological_process | uridine catabolic process |
N | 0006974 | biological_process | DNA damage response |
N | 0009116 | biological_process | nucleoside metabolic process |
N | 0009164 | biological_process | nucleoside catabolic process |
N | 0009166 | biological_process | nucleotide catabolic process |
N | 0016757 | molecular_function | glycosyltransferase activity |
N | 0016763 | molecular_function | pentosyltransferase activity |
N | 0030955 | molecular_function | potassium ion binding |
N | 0032991 | cellular_component | protein-containing complex |
N | 0042802 | molecular_function | identical protein binding |
N | 0044206 | biological_process | UMP salvage |
N | 0046050 | biological_process | UMP catabolic process |
N | 0047847 | molecular_function | deoxyuridine phosphorylase activity |
O | 0003824 | molecular_function | catalytic activity |
O | 0004850 | molecular_function | uridine phosphorylase activity |
O | 0005524 | molecular_function | ATP binding |
O | 0005737 | cellular_component | cytoplasm |
O | 0005829 | cellular_component | cytosol |
O | 0006218 | biological_process | uridine catabolic process |
O | 0006974 | biological_process | DNA damage response |
O | 0009116 | biological_process | nucleoside metabolic process |
O | 0009164 | biological_process | nucleoside catabolic process |
O | 0009166 | biological_process | nucleotide catabolic process |
O | 0016757 | molecular_function | glycosyltransferase activity |
O | 0016763 | molecular_function | pentosyltransferase activity |
O | 0030955 | molecular_function | potassium ion binding |
O | 0032991 | cellular_component | protein-containing complex |
O | 0042802 | molecular_function | identical protein binding |
O | 0044206 | biological_process | UMP salvage |
O | 0046050 | biological_process | UMP catabolic process |
O | 0047847 | molecular_function | deoxyuridine phosphorylase activity |
P | 0003824 | molecular_function | catalytic activity |
P | 0004850 | molecular_function | uridine phosphorylase activity |
P | 0005524 | molecular_function | ATP binding |
P | 0005737 | cellular_component | cytoplasm |
P | 0005829 | cellular_component | cytosol |
P | 0006218 | biological_process | uridine catabolic process |
P | 0006974 | biological_process | DNA damage response |
P | 0009116 | biological_process | nucleoside metabolic process |
P | 0009164 | biological_process | nucleoside catabolic process |
P | 0009166 | biological_process | nucleotide catabolic process |
P | 0016757 | molecular_function | glycosyltransferase activity |
P | 0016763 | molecular_function | pentosyltransferase activity |
P | 0030955 | molecular_function | potassium ion binding |
P | 0032991 | cellular_component | protein-containing complex |
P | 0042802 | molecular_function | identical protein binding |
P | 0044206 | biological_process | UMP salvage |
P | 0046050 | biological_process | UMP catabolic process |
P | 0047847 | molecular_function | deoxyuridine phosphorylase activity |
Q | 0003824 | molecular_function | catalytic activity |
Q | 0004850 | molecular_function | uridine phosphorylase activity |
Q | 0005524 | molecular_function | ATP binding |
Q | 0005737 | cellular_component | cytoplasm |
Q | 0005829 | cellular_component | cytosol |
Q | 0006218 | biological_process | uridine catabolic process |
Q | 0006974 | biological_process | DNA damage response |
Q | 0009116 | biological_process | nucleoside metabolic process |
Q | 0009164 | biological_process | nucleoside catabolic process |
Q | 0009166 | biological_process | nucleotide catabolic process |
Q | 0016757 | molecular_function | glycosyltransferase activity |
Q | 0016763 | molecular_function | pentosyltransferase activity |
Q | 0030955 | molecular_function | potassium ion binding |
Q | 0032991 | cellular_component | protein-containing complex |
Q | 0042802 | molecular_function | identical protein binding |
Q | 0044206 | biological_process | UMP salvage |
Q | 0046050 | biological_process | UMP catabolic process |
Q | 0047847 | molecular_function | deoxyuridine phosphorylase activity |
R | 0003824 | molecular_function | catalytic activity |
R | 0004850 | molecular_function | uridine phosphorylase activity |
R | 0005524 | molecular_function | ATP binding |
R | 0005737 | cellular_component | cytoplasm |
R | 0005829 | cellular_component | cytosol |
R | 0006218 | biological_process | uridine catabolic process |
R | 0006974 | biological_process | DNA damage response |
R | 0009116 | biological_process | nucleoside metabolic process |
R | 0009164 | biological_process | nucleoside catabolic process |
R | 0009166 | biological_process | nucleotide catabolic process |
R | 0016757 | molecular_function | glycosyltransferase activity |
R | 0016763 | molecular_function | pentosyltransferase activity |
R | 0030955 | molecular_function | potassium ion binding |
R | 0032991 | cellular_component | protein-containing complex |
R | 0042802 | molecular_function | identical protein binding |
R | 0044206 | biological_process | UMP salvage |
R | 0046050 | biological_process | UMP catabolic process |
R | 0047847 | molecular_function | deoxyuridine phosphorylase activity |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 9 |
Details | BINDING SITE FOR RESIDUE PO4 A 2011 |
Chain | Residue |
A | GLY26 |
A | ASP27 |
A | ARG30 |
A | ARG91 |
A | ILE92 |
A | GLY93 |
A | THR94 |
A | THM2012 |
B | ARG48 |
site_id | AC2 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE PO4 B 2021 |
Chain | Residue |
A | ARG48 |
B | GLY26 |
B | ARG30 |
B | ARG91 |
B | ILE92 |
B | GLY93 |
B | THR94 |
B | THM2022 |
site_id | AC3 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE PO4 C 2031 |
Chain | Residue |
C | GLY26 |
C | ARG30 |
C | ARG91 |
C | ILE92 |
C | GLY93 |
C | THR94 |
C | THM2032 |
D | ARG48 |
site_id | AC4 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE PO4 D 2041 |
Chain | Residue |
C | ARG48 |
D | GLY26 |
D | ARG30 |
D | ARG91 |
D | ILE92 |
D | GLY93 |
D | THR94 |
D | THM2042 |
site_id | AC5 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE PO4 E 2051 |
Chain | Residue |
E | GLY26 |
E | ARG30 |
E | ARG91 |
E | ILE92 |
E | GLY93 |
E | THR94 |
E | THM2052 |
F | ARG48 |
site_id | AC6 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE PO4 F 2061 |
Chain | Residue |
E | ARG48 |
F | GLY26 |
F | ARG30 |
F | ARG91 |
F | ILE92 |
F | GLY93 |
F | THR94 |
F | THM2062 |
site_id | AC7 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE PO4 G 2071 |
Chain | Residue |
G | GLY26 |
G | ARG30 |
G | ARG91 |
G | ILE92 |
G | GLY93 |
G | THR94 |
G | THM2072 |
H | ARG48 |
site_id | AC8 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE PO4 H 2081 |
Chain | Residue |
G | ARG48 |
H | GLY26 |
H | ARG30 |
H | ARG91 |
H | ILE92 |
H | GLY93 |
H | THR94 |
H | THM2082 |
site_id | AC9 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE PO4 I 2091 |
Chain | Residue |
I | GLY26 |
I | ARG30 |
I | ARG91 |
I | ILE92 |
I | GLY93 |
I | THR94 |
I | THM2092 |
J | ARG48 |
site_id | BC1 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE PO4 J 2101 |
Chain | Residue |
I | ARG48 |
J | GLY26 |
J | ARG30 |
J | ARG91 |
J | ILE92 |
J | GLY93 |
J | THR94 |
J | THM2102 |
site_id | BC2 |
Number of Residues | 9 |
Details | BINDING SITE FOR RESIDUE PO4 K 2111 |
Chain | Residue |
K | GLY26 |
K | ASP27 |
K | ARG30 |
K | ARG91 |
K | ILE92 |
K | GLY93 |
K | THR94 |
K | THM2112 |
L | ARG48 |
site_id | BC3 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE PO4 L 2121 |
Chain | Residue |
K | ARG48 |
L | GLY26 |
L | ARG30 |
L | ARG91 |
L | ILE92 |
L | GLY93 |
L | THR94 |
L | THM2122 |
site_id | BC4 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE PO4 M 2131 |
Chain | Residue |
M | ARG30 |
M | ARG91 |
M | ILE92 |
M | GLY93 |
M | THR94 |
M | THM2132 |
N | ARG48 |
M | GLY26 |
site_id | BC5 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE PO4 N 2141 |
Chain | Residue |
M | ARG48 |
N | GLY26 |
N | ARG30 |
N | ARG91 |
N | ILE92 |
N | GLY93 |
N | THR94 |
N | THM2142 |
site_id | BC6 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE PO4 O 2151 |
Chain | Residue |
O | GLY26 |
O | ARG30 |
O | ARG91 |
O | ILE92 |
O | GLY93 |
O | THR94 |
O | THM2152 |
P | ARG48 |
site_id | BC7 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE PO4 P 2161 |
Chain | Residue |
O | ARG48 |
P | GLY26 |
P | ARG30 |
P | ARG91 |
P | ILE92 |
P | GLY93 |
P | THR94 |
P | THM2162 |
site_id | BC8 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE PO4 Q 2171 |
Chain | Residue |
Q | GLY26 |
Q | ARG30 |
Q | ARG91 |
Q | ILE92 |
Q | GLY93 |
Q | THR94 |
Q | THM2172 |
R | ARG48 |
site_id | BC9 |
Number of Residues | 9 |
Details | BINDING SITE FOR RESIDUE PO4 R 2181 |
Chain | Residue |
Q | ARG48 |
R | GLY26 |
R | ASP27 |
R | ARG30 |
R | ARG91 |
R | ILE92 |
R | GLY93 |
R | THR94 |
R | THM2182 |
site_id | CC1 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE K A 3001 |
Chain | Residue |
A | GLU49 |
A | ILE69 |
A | SER73 |
B | GLU49 |
B | ILE69 |
B | SER73 |
site_id | CC2 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE K C 3002 |
Chain | Residue |
C | GLU49 |
C | ILE69 |
C | SER73 |
D | GLU49 |
D | ILE69 |
D | SER73 |
site_id | CC3 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE K F 3003 |
Chain | Residue |
E | GLU49 |
E | ILE69 |
E | SER73 |
F | GLU49 |
F | ILE69 |
F | SER73 |
site_id | CC4 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE K G 3004 |
Chain | Residue |
G | GLU49 |
G | ILE69 |
G | SER73 |
H | GLU49 |
H | ILE69 |
H | SER73 |
site_id | CC5 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE K I 3005 |
Chain | Residue |
I | GLU49 |
I | ILE69 |
I | SER73 |
J | GLU49 |
J | ILE69 |
J | SER73 |
site_id | CC6 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE K K 3006 |
Chain | Residue |
K | GLU49 |
K | ILE69 |
K | SER73 |
L | GLU49 |
L | ILE69 |
L | SER73 |
site_id | CC7 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE K M 3007 |
Chain | Residue |
M | GLU49 |
M | ILE69 |
M | SER73 |
N | GLU49 |
N | ILE69 |
N | SER73 |
site_id | CC8 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE K Q 3008 |
Chain | Residue |
Q | GLU49 |
Q | ILE69 |
Q | SER73 |
R | GLU49 |
R | ILE69 |
R | SER73 |
site_id | CC9 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE K O 3009 |
Chain | Residue |
O | GLU49 |
O | ILE69 |
O | SER73 |
P | GLU49 |
P | ILE69 |
P | SER73 |
site_id | DC1 |
Number of Residues | 13 |
Details | BINDING SITE FOR RESIDUE THM A 2012 |
Chain | Residue |
A | ILE69 |
A | THR94 |
A | PHE162 |
A | GLN166 |
A | ARG168 |
A | GLU196 |
A | MET197 |
A | GLU198 |
A | ILE220 |
A | PO42011 |
A | HOH3009 |
B | HIS8 |
B | ARG48 |
site_id | DC2 |
Number of Residues | 13 |
Details | BINDING SITE FOR RESIDUE THM B 2022 |
Chain | Residue |
A | HIS8 |
B | ILE69 |
B | THR94 |
B | GLY96 |
B | PHE162 |
B | GLN166 |
B | ARG168 |
B | GLU196 |
B | MET197 |
B | GLU198 |
B | ILE220 |
B | PO42021 |
B | HOH2035 |
site_id | DC3 |
Number of Residues | 14 |
Details | BINDING SITE FOR RESIDUE THM C 2032 |
Chain | Residue |
C | ILE69 |
C | THR94 |
C | GLY96 |
C | PHE162 |
C | GLN166 |
C | ARG168 |
C | GLU196 |
C | MET197 |
C | GLU198 |
C | ILE220 |
C | PRO229 |
C | PO42031 |
C | HOH3017 |
D | HIS8 |
site_id | DC4 |
Number of Residues | 14 |
Details | BINDING SITE FOR RESIDUE THM D 2042 |
Chain | Residue |
C | HIS8 |
D | THR94 |
D | THR95 |
D | GLY96 |
D | GLN166 |
D | ARG168 |
D | TYR195 |
D | GLU196 |
D | MET197 |
D | GLU198 |
D | ILE220 |
D | VAL221 |
D | PO42041 |
D | HOH2052 |
site_id | DC5 |
Number of Residues | 14 |
Details | BINDING SITE FOR RESIDUE THM E 2052 |
Chain | Residue |
E | ILE69 |
E | THR94 |
E | GLY96 |
E | GLN166 |
E | ARG168 |
E | GLU196 |
E | MET197 |
E | GLU198 |
E | ILE220 |
E | VAL221 |
E | PRO229 |
E | PO42051 |
E | HOH2066 |
F | HIS8 |
site_id | DC6 |
Number of Residues | 15 |
Details | BINDING SITE FOR RESIDUE THM F 2062 |
Chain | Residue |
E | HIS8 |
F | ARG91 |
F | THR94 |
F | GLY96 |
F | PHE162 |
F | GLN166 |
F | ARG168 |
F | TYR195 |
F | GLU196 |
F | MET197 |
F | GLU198 |
F | ILE220 |
F | VAL221 |
F | PO42061 |
F | HOH3022 |
site_id | DC7 |
Number of Residues | 15 |
Details | BINDING SITE FOR RESIDUE THM G 2072 |
Chain | Residue |
G | ILE69 |
G | THR94 |
G | THR95 |
G | GLY96 |
G | PHE162 |
G | GLN166 |
G | ARG168 |
G | GLU196 |
G | MET197 |
G | GLU198 |
G | ILE220 |
G | VAL221 |
G | HOH611 |
G | PO42071 |
H | HIS8 |
site_id | DC8 |
Number of Residues | 16 |
Details | BINDING SITE FOR RESIDUE THM H 2082 |
Chain | Residue |
G | HIS8 |
G | ARG48 |
H | ILE69 |
H | THR94 |
H | GLY96 |
H | PHE162 |
H | GLN166 |
H | ARG168 |
H | TYR195 |
H | GLU196 |
H | MET197 |
H | GLU198 |
H | ILE220 |
H | PRO229 |
H | HOH711 |
H | PO42081 |
site_id | DC9 |
Number of Residues | 13 |
Details | BINDING SITE FOR RESIDUE THM I 2092 |
Chain | Residue |
I | ILE69 |
I | THR94 |
I | THR95 |
I | GLY96 |
I | GLN166 |
I | ARG168 |
I | GLU196 |
I | MET197 |
I | GLU198 |
I | ILE220 |
I | HOH811 |
I | PO42091 |
J | HIS8 |
site_id | EC1 |
Number of Residues | 13 |
Details | BINDING SITE FOR RESIDUE THM J 2102 |
Chain | Residue |
I | HIS8 |
J | ILE69 |
J | THR94 |
J | GLY96 |
J | PHE162 |
J | GLN166 |
J | ARG168 |
J | GLU196 |
J | MET197 |
J | GLU198 |
J | ILE220 |
J | VAL221 |
J | PO42101 |
site_id | EC2 |
Number of Residues | 14 |
Details | BINDING SITE FOR RESIDUE THM K 2112 |
Chain | Residue |
K | ILE69 |
K | THR94 |
K | THR95 |
K | GLY96 |
K | PHE162 |
K | GLN166 |
K | ARG168 |
K | GLU196 |
K | MET197 |
K | GLU198 |
K | ILE220 |
K | HOH1011 |
K | PO42111 |
L | HIS8 |
site_id | EC3 |
Number of Residues | 13 |
Details | BINDING SITE FOR RESIDUE THM L 2122 |
Chain | Residue |
K | HIS8 |
L | THR94 |
L | GLY96 |
L | PHE162 |
L | GLN166 |
L | ARG168 |
L | GLU196 |
L | MET197 |
L | GLU198 |
L | ILE220 |
L | VAL221 |
L | PRO229 |
L | PO42121 |
site_id | EC4 |
Number of Residues | 14 |
Details | BINDING SITE FOR RESIDUE THM M 2132 |
Chain | Residue |
M | ILE69 |
M | THR94 |
M | GLY96 |
M | PHE162 |
M | GLN166 |
M | ARG168 |
M | TYR195 |
M | GLU196 |
M | MET197 |
M | GLU198 |
M | ILE220 |
M | HOH1211 |
M | PO42131 |
N | HIS8 |
site_id | EC5 |
Number of Residues | 13 |
Details | BINDING SITE FOR RESIDUE THM N 2142 |
Chain | Residue |
M | HIS8 |
N | ILE69 |
N | THR94 |
N | PHE162 |
N | GLN166 |
N | ARG168 |
N | GLU196 |
N | MET197 |
N | GLU198 |
N | ILE220 |
N | VAL221 |
N | HOH1311 |
N | PO42141 |
site_id | EC6 |
Number of Residues | 15 |
Details | BINDING SITE FOR RESIDUE THM O 2152 |
Chain | Residue |
O | ILE69 |
O | THR94 |
O | GLY96 |
O | PHE162 |
O | GLN166 |
O | ARG168 |
O | TYR195 |
O | GLU196 |
O | MET197 |
O | GLU198 |
O | ILE220 |
O | VAL221 |
O | HOH1411 |
O | PO42151 |
P | HIS8 |
site_id | EC7 |
Number of Residues | 14 |
Details | BINDING SITE FOR RESIDUE THM P 2162 |
Chain | Residue |
O | HIS8 |
P | THR94 |
P | GLY96 |
P | PHE162 |
P | GLN166 |
P | ARG168 |
P | GLU196 |
P | MET197 |
P | GLU198 |
P | ILE220 |
P | VAL221 |
P | PRO229 |
P | HOH1511 |
P | PO42161 |
site_id | EC8 |
Number of Residues | 14 |
Details | BINDING SITE FOR RESIDUE THM Q 2172 |
Chain | Residue |
Q | ILE69 |
Q | THR94 |
Q | GLY96 |
Q | PHE162 |
Q | GLN166 |
Q | ARG168 |
Q | TYR195 |
Q | GLU196 |
Q | MET197 |
Q | GLU198 |
Q | ILE220 |
Q | HOH1611 |
Q | PO42171 |
R | HIS8 |
site_id | EC9 |
Number of Residues | 14 |
Details | BINDING SITE FOR RESIDUE THM R 2182 |
Chain | Residue |
Q | HIS8 |
R | ILE69 |
R | THR94 |
R | THR95 |
R | GLY96 |
R | PHE162 |
R | GLN166 |
R | ARG168 |
R | GLU196 |
R | MET197 |
R | GLU198 |
R | ILE220 |
R | HOH1711 |
R | PO42181 |
Functional Information from PROSITE/UniProt
site_id | PS01232 |
Number of Residues | 16 |
Details | PNP_UDP_1 Purine and other phosphorylases family 1 signature. StGIGgPStSIaveEL |
Chain | Residue | Details |
A | SER66-LEU81 |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1t0u |
Chain | Residue | Details |
A | GLU80 | |
A | HIS8 | |
A | ARG223 |
site_id | CSA10 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1t0u |
Chain | Residue | Details |
J | GLU80 | |
J | HIS8 | |
J | ARG223 |
site_id | CSA11 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1t0u |
Chain | Residue | Details |
K | GLU80 | |
K | HIS8 | |
K | ARG223 |
site_id | CSA12 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1t0u |
Chain | Residue | Details |
L | GLU80 | |
L | HIS8 | |
L | ARG223 |
site_id | CSA13 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1t0u |
Chain | Residue | Details |
M | GLU80 | |
M | HIS8 | |
M | ARG223 |
site_id | CSA14 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1t0u |
Chain | Residue | Details |
N | GLU80 | |
N | HIS8 | |
N | ARG223 |
site_id | CSA15 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1t0u |
Chain | Residue | Details |
O | GLU80 | |
O | HIS8 | |
O | ARG223 |
site_id | CSA16 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1t0u |
Chain | Residue | Details |
P | GLU80 | |
P | HIS8 | |
P | ARG223 |
site_id | CSA17 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1t0u |
Chain | Residue | Details |
Q | GLU80 | |
Q | HIS8 | |
Q | ARG223 |
site_id | CSA18 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1t0u |
Chain | Residue | Details |
R | GLU80 | |
R | HIS8 | |
R | ARG223 |
site_id | CSA2 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1t0u |
Chain | Residue | Details |
B | GLU80 | |
B | HIS8 | |
B | ARG223 |
site_id | CSA3 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1t0u |
Chain | Residue | Details |
C | GLU80 | |
C | HIS8 | |
C | ARG223 |
site_id | CSA4 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1t0u |
Chain | Residue | Details |
D | GLU80 | |
D | HIS8 | |
D | ARG223 |
site_id | CSA5 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1t0u |
Chain | Residue | Details |
E | GLU80 | |
E | HIS8 | |
E | ARG223 |
site_id | CSA6 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1t0u |
Chain | Residue | Details |
F | GLU80 | |
F | HIS8 | |
F | ARG223 |
site_id | CSA7 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1t0u |
Chain | Residue | Details |
G | GLU80 | |
G | HIS8 | |
G | ARG223 |
site_id | CSA8 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1t0u |
Chain | Residue | Details |
H | GLU80 | |
H | HIS8 | |
H | ARG223 |
site_id | CSA9 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1t0u |
Chain | Residue | Details |
I | GLU80 | |
I | HIS8 | |
I | ARG223 |
site_id | MCSA1 |
Number of Residues | 4 |
Details | M-CSA 787 |
Chain | Residue | Details |
A | LEU9 | proton acceptor, proton donor |
A | LEU81 | electrostatic stabiliser, polar interaction |
A | TYR169 | proton acceptor, proton donor |
A | THR224 | electrostatic stabiliser, polar interaction |
site_id | MCSA10 |
Number of Residues | 4 |
Details | M-CSA 787 |
Chain | Residue | Details |
J | LEU9 | proton acceptor, proton donor |
J | LEU81 | electrostatic stabiliser, polar interaction |
J | TYR169 | proton acceptor, proton donor |
J | THR224 | electrostatic stabiliser, polar interaction |
site_id | MCSA11 |
Number of Residues | 4 |
Details | M-CSA 787 |
Chain | Residue | Details |
K | LEU9 | proton acceptor, proton donor |
K | LEU81 | electrostatic stabiliser, polar interaction |
K | TYR169 | proton acceptor, proton donor |
K | THR224 | electrostatic stabiliser, polar interaction |
site_id | MCSA12 |
Number of Residues | 4 |
Details | M-CSA 787 |
Chain | Residue | Details |
L | LEU9 | proton acceptor, proton donor |
L | LEU81 | electrostatic stabiliser, polar interaction |
L | TYR169 | proton acceptor, proton donor |
L | THR224 | electrostatic stabiliser, polar interaction |
site_id | MCSA13 |
Number of Residues | 4 |
Details | M-CSA 787 |
Chain | Residue | Details |
M | LEU9 | proton acceptor, proton donor |
M | LEU81 | electrostatic stabiliser, polar interaction |
M | TYR169 | proton acceptor, proton donor |
M | THR224 | electrostatic stabiliser, polar interaction |
site_id | MCSA14 |
Number of Residues | 4 |
Details | M-CSA 787 |
Chain | Residue | Details |
N | LEU9 | proton acceptor, proton donor |
N | LEU81 | electrostatic stabiliser, polar interaction |
N | TYR169 | proton acceptor, proton donor |
N | THR224 | electrostatic stabiliser, polar interaction |
site_id | MCSA15 |
Number of Residues | 4 |
Details | M-CSA 787 |
Chain | Residue | Details |
O | LEU9 | proton acceptor, proton donor |
O | LEU81 | electrostatic stabiliser, polar interaction |
O | TYR169 | proton acceptor, proton donor |
O | THR224 | electrostatic stabiliser, polar interaction |
site_id | MCSA16 |
Number of Residues | 4 |
Details | M-CSA 787 |
Chain | Residue | Details |
P | LEU9 | proton acceptor, proton donor |
P | LEU81 | electrostatic stabiliser, polar interaction |
P | TYR169 | proton acceptor, proton donor |
P | THR224 | electrostatic stabiliser, polar interaction |
site_id | MCSA17 |
Number of Residues | 4 |
Details | M-CSA 787 |
Chain | Residue | Details |
Q | LEU9 | proton acceptor, proton donor |
Q | LEU81 | electrostatic stabiliser, polar interaction |
Q | TYR169 | proton acceptor, proton donor |
Q | THR224 | electrostatic stabiliser, polar interaction |
site_id | MCSA18 |
Number of Residues | 4 |
Details | M-CSA 787 |
Chain | Residue | Details |
R | LEU9 | proton acceptor, proton donor |
R | LEU81 | electrostatic stabiliser, polar interaction |
R | TYR169 | proton acceptor, proton donor |
R | THR224 | electrostatic stabiliser, polar interaction |
site_id | MCSA2 |
Number of Residues | 4 |
Details | M-CSA 787 |
Chain | Residue | Details |
B | LEU9 | proton acceptor, proton donor |
B | LEU81 | electrostatic stabiliser, polar interaction |
B | TYR169 | proton acceptor, proton donor |
B | THR224 | electrostatic stabiliser, polar interaction |
site_id | MCSA3 |
Number of Residues | 4 |
Details | M-CSA 787 |
Chain | Residue | Details |
C | LEU9 | proton acceptor, proton donor |
C | LEU81 | electrostatic stabiliser, polar interaction |
C | TYR169 | proton acceptor, proton donor |
C | THR224 | electrostatic stabiliser, polar interaction |
site_id | MCSA4 |
Number of Residues | 4 |
Details | M-CSA 787 |
Chain | Residue | Details |
D | LEU9 | proton acceptor, proton donor |
D | LEU81 | electrostatic stabiliser, polar interaction |
D | TYR169 | proton acceptor, proton donor |
D | THR224 | electrostatic stabiliser, polar interaction |
site_id | MCSA5 |
Number of Residues | 4 |
Details | M-CSA 787 |
Chain | Residue | Details |
E | LEU9 | proton acceptor, proton donor |
E | LEU81 | electrostatic stabiliser, polar interaction |
E | TYR169 | proton acceptor, proton donor |
E | THR224 | electrostatic stabiliser, polar interaction |
site_id | MCSA6 |
Number of Residues | 4 |
Details | M-CSA 787 |
Chain | Residue | Details |
F | LEU9 | proton acceptor, proton donor |
F | LEU81 | electrostatic stabiliser, polar interaction |
F | TYR169 | proton acceptor, proton donor |
F | THR224 | electrostatic stabiliser, polar interaction |
site_id | MCSA7 |
Number of Residues | 4 |
Details | M-CSA 787 |
Chain | Residue | Details |
G | LEU9 | proton acceptor, proton donor |
G | LEU81 | electrostatic stabiliser, polar interaction |
G | TYR169 | proton acceptor, proton donor |
G | THR224 | electrostatic stabiliser, polar interaction |
site_id | MCSA8 |
Number of Residues | 4 |
Details | M-CSA 787 |
Chain | Residue | Details |
H | LEU9 | proton acceptor, proton donor |
H | LEU81 | electrostatic stabiliser, polar interaction |
H | TYR169 | proton acceptor, proton donor |
H | THR224 | electrostatic stabiliser, polar interaction |
site_id | MCSA9 |
Number of Residues | 4 |
Details | M-CSA 787 |
Chain | Residue | Details |
I | LEU9 | proton acceptor, proton donor |
I | LEU81 | electrostatic stabiliser, polar interaction |
I | TYR169 | proton acceptor, proton donor |
I | THR224 | electrostatic stabiliser, polar interaction |