Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

1RXU

E. coli uridine phosphorylase: thymidine phosphate complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0004850	molecular_function	uridine phosphorylase activity
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006218	biological_process	uridine catabolic process
A	0006974	biological_process	DNA damage response
A	0009116	biological_process	nucleoside metabolic process
A	0009164	biological_process	nucleoside catabolic process
A	0009166	biological_process	nucleotide catabolic process
A	0016740	molecular_function	transferase activity
A	0016757	molecular_function	glycosyltransferase activity
A	0016763	molecular_function	pentosyltransferase activity
A	0030955	molecular_function	potassium ion binding
A	0032991	cellular_component	protein-containing complex
A	0042802	molecular_function	identical protein binding
A	0044206	biological_process	UMP salvage
A	0046050	biological_process	UMP catabolic process
B	0003824	molecular_function	catalytic activity
B	0004850	molecular_function	uridine phosphorylase activity
B	0005524	molecular_function	ATP binding
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0006218	biological_process	uridine catabolic process
B	0006974	biological_process	DNA damage response
B	0009116	biological_process	nucleoside metabolic process
B	0009164	biological_process	nucleoside catabolic process
B	0009166	biological_process	nucleotide catabolic process
B	0016740	molecular_function	transferase activity
B	0016757	molecular_function	glycosyltransferase activity
B	0016763	molecular_function	pentosyltransferase activity
B	0030955	molecular_function	potassium ion binding
B	0032991	cellular_component	protein-containing complex
B	0042802	molecular_function	identical protein binding
B	0044206	biological_process	UMP salvage
B	0046050	biological_process	UMP catabolic process
C	0003824	molecular_function	catalytic activity
C	0004850	molecular_function	uridine phosphorylase activity
C	0005524	molecular_function	ATP binding
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0006218	biological_process	uridine catabolic process
C	0006974	biological_process	DNA damage response
C	0009116	biological_process	nucleoside metabolic process
C	0009164	biological_process	nucleoside catabolic process
C	0009166	biological_process	nucleotide catabolic process
C	0016740	molecular_function	transferase activity
C	0016757	molecular_function	glycosyltransferase activity
C	0016763	molecular_function	pentosyltransferase activity
C	0030955	molecular_function	potassium ion binding
C	0032991	cellular_component	protein-containing complex
C	0042802	molecular_function	identical protein binding
C	0044206	biological_process	UMP salvage
C	0046050	biological_process	UMP catabolic process
D	0003824	molecular_function	catalytic activity
D	0004850	molecular_function	uridine phosphorylase activity
D	0005524	molecular_function	ATP binding
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0006218	biological_process	uridine catabolic process
D	0006974	biological_process	DNA damage response
D	0009116	biological_process	nucleoside metabolic process
D	0009164	biological_process	nucleoside catabolic process
D	0009166	biological_process	nucleotide catabolic process
D	0016740	molecular_function	transferase activity
D	0016757	molecular_function	glycosyltransferase activity
D	0016763	molecular_function	pentosyltransferase activity
D	0030955	molecular_function	potassium ion binding
D	0032991	cellular_component	protein-containing complex
D	0042802	molecular_function	identical protein binding
D	0044206	biological_process	UMP salvage
D	0046050	biological_process	UMP catabolic process
E	0003824	molecular_function	catalytic activity
E	0004850	molecular_function	uridine phosphorylase activity
E	0005524	molecular_function	ATP binding
E	0005737	cellular_component	cytoplasm
E	0005829	cellular_component	cytosol
E	0006218	biological_process	uridine catabolic process
E	0006974	biological_process	DNA damage response
E	0009116	biological_process	nucleoside metabolic process
E	0009164	biological_process	nucleoside catabolic process
E	0009166	biological_process	nucleotide catabolic process
E	0016740	molecular_function	transferase activity
E	0016757	molecular_function	glycosyltransferase activity
E	0016763	molecular_function	pentosyltransferase activity
E	0030955	molecular_function	potassium ion binding
E	0032991	cellular_component	protein-containing complex
E	0042802	molecular_function	identical protein binding
E	0044206	biological_process	UMP salvage
E	0046050	biological_process	UMP catabolic process
F	0003824	molecular_function	catalytic activity
F	0004850	molecular_function	uridine phosphorylase activity
F	0005524	molecular_function	ATP binding
F	0005737	cellular_component	cytoplasm
F	0005829	cellular_component	cytosol
F	0006218	biological_process	uridine catabolic process
F	0006974	biological_process	DNA damage response
F	0009116	biological_process	nucleoside metabolic process
F	0009164	biological_process	nucleoside catabolic process
F	0009166	biological_process	nucleotide catabolic process
F	0016740	molecular_function	transferase activity
F	0016757	molecular_function	glycosyltransferase activity
F	0016763	molecular_function	pentosyltransferase activity
F	0030955	molecular_function	potassium ion binding
F	0032991	cellular_component	protein-containing complex
F	0042802	molecular_function	identical protein binding
F	0044206	biological_process	UMP salvage
F	0046050	biological_process	UMP catabolic process
G	0003824	molecular_function	catalytic activity
G	0004850	molecular_function	uridine phosphorylase activity
G	0005524	molecular_function	ATP binding
G	0005737	cellular_component	cytoplasm
G	0005829	cellular_component	cytosol
G	0006218	biological_process	uridine catabolic process
G	0006974	biological_process	DNA damage response
G	0009116	biological_process	nucleoside metabolic process
G	0009164	biological_process	nucleoside catabolic process
G	0009166	biological_process	nucleotide catabolic process
G	0016740	molecular_function	transferase activity
G	0016757	molecular_function	glycosyltransferase activity
G	0016763	molecular_function	pentosyltransferase activity
G	0030955	molecular_function	potassium ion binding
G	0032991	cellular_component	protein-containing complex
G	0042802	molecular_function	identical protein binding
G	0044206	biological_process	UMP salvage
G	0046050	biological_process	UMP catabolic process
H	0003824	molecular_function	catalytic activity
H	0004850	molecular_function	uridine phosphorylase activity
H	0005524	molecular_function	ATP binding
H	0005737	cellular_component	cytoplasm
H	0005829	cellular_component	cytosol
H	0006218	biological_process	uridine catabolic process
H	0006974	biological_process	DNA damage response
H	0009116	biological_process	nucleoside metabolic process
H	0009164	biological_process	nucleoside catabolic process
H	0009166	biological_process	nucleotide catabolic process
H	0016740	molecular_function	transferase activity
H	0016757	molecular_function	glycosyltransferase activity
H	0016763	molecular_function	pentosyltransferase activity
H	0030955	molecular_function	potassium ion binding
H	0032991	cellular_component	protein-containing complex
H	0042802	molecular_function	identical protein binding
H	0044206	biological_process	UMP salvage
H	0046050	biological_process	UMP catabolic process
I	0003824	molecular_function	catalytic activity
I	0004850	molecular_function	uridine phosphorylase activity
I	0005524	molecular_function	ATP binding
I	0005737	cellular_component	cytoplasm
I	0005829	cellular_component	cytosol
I	0006218	biological_process	uridine catabolic process
I	0006974	biological_process	DNA damage response
I	0009116	biological_process	nucleoside metabolic process
I	0009164	biological_process	nucleoside catabolic process
I	0009166	biological_process	nucleotide catabolic process
I	0016740	molecular_function	transferase activity
I	0016757	molecular_function	glycosyltransferase activity
I	0016763	molecular_function	pentosyltransferase activity
I	0030955	molecular_function	potassium ion binding
I	0032991	cellular_component	protein-containing complex
I	0042802	molecular_function	identical protein binding
I	0044206	biological_process	UMP salvage
I	0046050	biological_process	UMP catabolic process
J	0003824	molecular_function	catalytic activity
J	0004850	molecular_function	uridine phosphorylase activity
J	0005524	molecular_function	ATP binding
J	0005737	cellular_component	cytoplasm
J	0005829	cellular_component	cytosol
J	0006218	biological_process	uridine catabolic process
J	0006974	biological_process	DNA damage response
J	0009116	biological_process	nucleoside metabolic process
J	0009164	biological_process	nucleoside catabolic process
J	0009166	biological_process	nucleotide catabolic process
J	0016740	molecular_function	transferase activity
J	0016757	molecular_function	glycosyltransferase activity
J	0016763	molecular_function	pentosyltransferase activity
J	0030955	molecular_function	potassium ion binding
J	0032991	cellular_component	protein-containing complex
J	0042802	molecular_function	identical protein binding
J	0044206	biological_process	UMP salvage
J	0046050	biological_process	UMP catabolic process
K	0003824	molecular_function	catalytic activity
K	0004850	molecular_function	uridine phosphorylase activity
K	0005524	molecular_function	ATP binding
K	0005737	cellular_component	cytoplasm
K	0005829	cellular_component	cytosol
K	0006218	biological_process	uridine catabolic process
K	0006974	biological_process	DNA damage response
K	0009116	biological_process	nucleoside metabolic process
K	0009164	biological_process	nucleoside catabolic process
K	0009166	biological_process	nucleotide catabolic process
K	0016740	molecular_function	transferase activity
K	0016757	molecular_function	glycosyltransferase activity
K	0016763	molecular_function	pentosyltransferase activity
K	0030955	molecular_function	potassium ion binding
K	0032991	cellular_component	protein-containing complex
K	0042802	molecular_function	identical protein binding
K	0044206	biological_process	UMP salvage
K	0046050	biological_process	UMP catabolic process
L	0003824	molecular_function	catalytic activity
L	0004850	molecular_function	uridine phosphorylase activity
L	0005524	molecular_function	ATP binding
L	0005737	cellular_component	cytoplasm
L	0005829	cellular_component	cytosol
L	0006218	biological_process	uridine catabolic process
L	0006974	biological_process	DNA damage response
L	0009116	biological_process	nucleoside metabolic process
L	0009164	biological_process	nucleoside catabolic process
L	0009166	biological_process	nucleotide catabolic process
L	0016740	molecular_function	transferase activity
L	0016757	molecular_function	glycosyltransferase activity
L	0016763	molecular_function	pentosyltransferase activity
L	0030955	molecular_function	potassium ion binding
L	0032991	cellular_component	protein-containing complex
L	0042802	molecular_function	identical protein binding
L	0044206	biological_process	UMP salvage
L	0046050	biological_process	UMP catabolic process
M	0003824	molecular_function	catalytic activity
M	0004850	molecular_function	uridine phosphorylase activity
M	0005524	molecular_function	ATP binding
M	0005737	cellular_component	cytoplasm
M	0005829	cellular_component	cytosol
M	0006218	biological_process	uridine catabolic process
M	0006974	biological_process	DNA damage response
M	0009116	biological_process	nucleoside metabolic process
M	0009164	biological_process	nucleoside catabolic process
M	0009166	biological_process	nucleotide catabolic process
M	0016740	molecular_function	transferase activity
M	0016757	molecular_function	glycosyltransferase activity
M	0016763	molecular_function	pentosyltransferase activity
M	0030955	molecular_function	potassium ion binding
M	0032991	cellular_component	protein-containing complex
M	0042802	molecular_function	identical protein binding
M	0044206	biological_process	UMP salvage
M	0046050	biological_process	UMP catabolic process
N	0003824	molecular_function	catalytic activity
N	0004850	molecular_function	uridine phosphorylase activity
N	0005524	molecular_function	ATP binding
N	0005737	cellular_component	cytoplasm
N	0005829	cellular_component	cytosol
N	0006218	biological_process	uridine catabolic process
N	0006974	biological_process	DNA damage response
N	0009116	biological_process	nucleoside metabolic process
N	0009164	biological_process	nucleoside catabolic process
N	0009166	biological_process	nucleotide catabolic process
N	0016740	molecular_function	transferase activity
N	0016757	molecular_function	glycosyltransferase activity
N	0016763	molecular_function	pentosyltransferase activity
N	0030955	molecular_function	potassium ion binding
N	0032991	cellular_component	protein-containing complex
N	0042802	molecular_function	identical protein binding
N	0044206	biological_process	UMP salvage
N	0046050	biological_process	UMP catabolic process
O	0003824	molecular_function	catalytic activity
O	0004850	molecular_function	uridine phosphorylase activity
O	0005524	molecular_function	ATP binding
O	0005737	cellular_component	cytoplasm
O	0005829	cellular_component	cytosol
O	0006218	biological_process	uridine catabolic process
O	0006974	biological_process	DNA damage response
O	0009116	biological_process	nucleoside metabolic process
O	0009164	biological_process	nucleoside catabolic process
O	0009166	biological_process	nucleotide catabolic process
O	0016740	molecular_function	transferase activity
O	0016757	molecular_function	glycosyltransferase activity
O	0016763	molecular_function	pentosyltransferase activity
O	0030955	molecular_function	potassium ion binding
O	0032991	cellular_component	protein-containing complex
O	0042802	molecular_function	identical protein binding
O	0044206	biological_process	UMP salvage
O	0046050	biological_process	UMP catabolic process
P	0003824	molecular_function	catalytic activity
P	0004850	molecular_function	uridine phosphorylase activity
P	0005524	molecular_function	ATP binding
P	0005737	cellular_component	cytoplasm
P	0005829	cellular_component	cytosol
P	0006218	biological_process	uridine catabolic process
P	0006974	biological_process	DNA damage response
P	0009116	biological_process	nucleoside metabolic process
P	0009164	biological_process	nucleoside catabolic process
P	0009166	biological_process	nucleotide catabolic process
P	0016740	molecular_function	transferase activity
P	0016757	molecular_function	glycosyltransferase activity
P	0016763	molecular_function	pentosyltransferase activity
P	0030955	molecular_function	potassium ion binding
P	0032991	cellular_component	protein-containing complex
P	0042802	molecular_function	identical protein binding
P	0044206	biological_process	UMP salvage
P	0046050	biological_process	UMP catabolic process
Q	0003824	molecular_function	catalytic activity
Q	0004850	molecular_function	uridine phosphorylase activity
Q	0005524	molecular_function	ATP binding
Q	0005737	cellular_component	cytoplasm
Q	0005829	cellular_component	cytosol
Q	0006218	biological_process	uridine catabolic process
Q	0006974	biological_process	DNA damage response
Q	0009116	biological_process	nucleoside metabolic process
Q	0009164	biological_process	nucleoside catabolic process
Q	0009166	biological_process	nucleotide catabolic process
Q	0016740	molecular_function	transferase activity
Q	0016757	molecular_function	glycosyltransferase activity
Q	0016763	molecular_function	pentosyltransferase activity
Q	0030955	molecular_function	potassium ion binding
Q	0032991	cellular_component	protein-containing complex
Q	0042802	molecular_function	identical protein binding
Q	0044206	biological_process	UMP salvage
Q	0046050	biological_process	UMP catabolic process
R	0003824	molecular_function	catalytic activity
R	0004850	molecular_function	uridine phosphorylase activity
R	0005524	molecular_function	ATP binding
R	0005737	cellular_component	cytoplasm
R	0005829	cellular_component	cytosol
R	0006218	biological_process	uridine catabolic process
R	0006974	biological_process	DNA damage response
R	0009116	biological_process	nucleoside metabolic process
R	0009164	biological_process	nucleoside catabolic process
R	0009166	biological_process	nucleotide catabolic process
R	0016740	molecular_function	transferase activity
R	0016757	molecular_function	glycosyltransferase activity
R	0016763	molecular_function	pentosyltransferase activity
R	0030955	molecular_function	potassium ion binding
R	0032991	cellular_component	protein-containing complex
R	0042802	molecular_function	identical protein binding
R	0044206	biological_process	UMP salvage
R	0046050	biological_process	UMP catabolic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	9
Details	BINDING SITE FOR RESIDUE PO4 A 2011

Chain	Residue
A	GLY26
A	ASP27
A	ARG30
A	ARG91
A	ILE92
A	GLY93
A	THR94
A	THM2012
B	ARG48

site_id	AC2
Number of Residues	8
Details	BINDING SITE FOR RESIDUE PO4 B 2021

Chain	Residue
A	ARG48
B	GLY26
B	ARG30
B	ARG91
B	ILE92
B	GLY93
B	THR94
B	THM2022

site_id	AC3
Number of Residues	8
Details	BINDING SITE FOR RESIDUE PO4 C 2031

Chain	Residue
C	GLY26
C	ARG30
C	ARG91
C	ILE92
C	GLY93
C	THR94
C	THM2032
D	ARG48

site_id	AC4
Number of Residues	8
Details	BINDING SITE FOR RESIDUE PO4 D 2041

Chain	Residue
C	ARG48
D	GLY26
D	ARG30
D	ARG91
D	ILE92
D	GLY93
D	THR94
D	THM2042

site_id	AC5
Number of Residues	8
Details	BINDING SITE FOR RESIDUE PO4 E 2051

Chain	Residue
E	GLY26
E	ARG30
E	ARG91
E	ILE92
E	GLY93
E	THR94
E	THM2052
F	ARG48

site_id	AC6
Number of Residues	8
Details	BINDING SITE FOR RESIDUE PO4 F 2061

Chain	Residue
E	ARG48
F	GLY26
F	ARG30
F	ARG91
F	ILE92
F	GLY93
F	THR94
F	THM2062

site_id	AC7
Number of Residues	8
Details	BINDING SITE FOR RESIDUE PO4 G 2071

Chain	Residue
G	GLY26
G	ARG30
G	ARG91
G	ILE92
G	GLY93
G	THR94
G	THM2072
H	ARG48

site_id	AC8
Number of Residues	8
Details	BINDING SITE FOR RESIDUE PO4 H 2081

Chain	Residue
G	ARG48
H	GLY26
H	ARG30
H	ARG91
H	ILE92
H	GLY93
H	THR94
H	THM2082

site_id	AC9
Number of Residues	8
Details	BINDING SITE FOR RESIDUE PO4 I 2091

Chain	Residue
I	GLY26
I	ARG30
I	ARG91
I	ILE92
I	GLY93
I	THR94
I	THM2092
J	ARG48

site_id	BC1
Number of Residues	8
Details	BINDING SITE FOR RESIDUE PO4 J 2101

Chain	Residue
I	ARG48
J	GLY26
J	ARG30
J	ARG91
J	ILE92
J	GLY93
J	THR94
J	THM2102

site_id	BC2
Number of Residues	9
Details	BINDING SITE FOR RESIDUE PO4 K 2111

Chain	Residue
K	GLY26
K	ASP27
K	ARG30
K	ARG91
K	ILE92
K	GLY93
K	THR94
K	THM2112
L	ARG48

site_id	BC3
Number of Residues	8
Details	BINDING SITE FOR RESIDUE PO4 L 2121

Chain	Residue
K	ARG48
L	GLY26
L	ARG30
L	ARG91
L	ILE92
L	GLY93
L	THR94
L	THM2122

site_id	BC4
Number of Residues	8
Details	BINDING SITE FOR RESIDUE PO4 M 2131

Chain	Residue
M	ARG30
M	ARG91
M	ILE92
M	GLY93
M	THR94
M	THM2132
N	ARG48
M	GLY26

site_id	BC5
Number of Residues	8
Details	BINDING SITE FOR RESIDUE PO4 N 2141

Chain	Residue
M	ARG48
N	GLY26
N	ARG30
N	ARG91
N	ILE92
N	GLY93
N	THR94
N	THM2142

site_id	BC6
Number of Residues	8
Details	BINDING SITE FOR RESIDUE PO4 O 2151

Chain	Residue
O	GLY26
O	ARG30
O	ARG91
O	ILE92
O	GLY93
O	THR94
O	THM2152
P	ARG48

site_id	BC7
Number of Residues	8
Details	BINDING SITE FOR RESIDUE PO4 P 2161

Chain	Residue
O	ARG48
P	GLY26
P	ARG30
P	ARG91
P	ILE92
P	GLY93
P	THR94
P	THM2162

site_id	BC8
Number of Residues	8
Details	BINDING SITE FOR RESIDUE PO4 Q 2171

Chain	Residue
Q	GLY26
Q	ARG30
Q	ARG91
Q	ILE92
Q	GLY93
Q	THR94
Q	THM2172
R	ARG48

site_id	BC9
Number of Residues	9
Details	BINDING SITE FOR RESIDUE PO4 R 2181

Chain	Residue
Q	ARG48
R	GLY26
R	ASP27
R	ARG30
R	ARG91
R	ILE92
R	GLY93
R	THR94
R	THM2182

site_id	CC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE K A 3001

Chain	Residue
A	GLU49
A	ILE69
A	SER73
B	GLU49
B	ILE69
B	SER73

site_id	CC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE K C 3002

Chain	Residue
C	GLU49
C	ILE69
C	SER73
D	GLU49
D	ILE69
D	SER73

site_id	CC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE K F 3003

Chain	Residue
E	GLU49
E	ILE69
E	SER73
F	GLU49
F	ILE69
F	SER73

site_id	CC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE K G 3004

Chain	Residue
G	GLU49
G	ILE69
G	SER73
H	GLU49
H	ILE69
H	SER73

site_id	CC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE K I 3005

Chain	Residue
I	GLU49
I	ILE69
I	SER73
J	GLU49
J	ILE69
J	SER73

site_id	CC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE K K 3006

Chain	Residue
K	GLU49
K	ILE69
K	SER73
L	GLU49
L	ILE69
L	SER73

site_id	CC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE K M 3007

Chain	Residue
M	GLU49
M	ILE69
M	SER73
N	GLU49
N	ILE69
N	SER73

site_id	CC8
Number of Residues	6
Details	BINDING SITE FOR RESIDUE K Q 3008

Chain	Residue
Q	GLU49
Q	ILE69
Q	SER73
R	GLU49
R	ILE69
R	SER73

site_id	CC9
Number of Residues	6
Details	BINDING SITE FOR RESIDUE K O 3009

Chain	Residue
O	GLU49
O	ILE69
O	SER73
P	GLU49
P	ILE69
P	SER73

site_id	DC1
Number of Residues	13
Details	BINDING SITE FOR RESIDUE THM A 2012

Chain	Residue
A	ILE69
A	THR94
A	PHE162
A	GLN166
A	ARG168
A	GLU196
A	MET197
A	GLU198
A	ILE220
A	PO42011
A	HOH3009
B	HIS8
B	ARG48

site_id	DC2
Number of Residues	13
Details	BINDING SITE FOR RESIDUE THM B 2022

Chain	Residue
A	HIS8
B	ILE69
B	THR94
B	GLY96
B	PHE162
B	GLN166
B	ARG168
B	GLU196
B	MET197
B	GLU198
B	ILE220
B	PO42021
B	HOH2035

site_id	DC3
Number of Residues	14
Details	BINDING SITE FOR RESIDUE THM C 2032

Chain	Residue
C	ILE69
C	THR94
C	GLY96
C	PHE162
C	GLN166
C	ARG168
C	GLU196
C	MET197
C	GLU198
C	ILE220
C	PRO229
C	PO42031
C	HOH3017
D	HIS8

site_id	DC4
Number of Residues	14
Details	BINDING SITE FOR RESIDUE THM D 2042

Chain	Residue
C	HIS8
D	THR94
D	THR95
D	GLY96
D	GLN166
D	ARG168
D	TYR195
D	GLU196
D	MET197
D	GLU198
D	ILE220
D	VAL221
D	PO42041
D	HOH2052

site_id	DC5
Number of Residues	14
Details	BINDING SITE FOR RESIDUE THM E 2052

Chain	Residue
E	ILE69
E	THR94
E	GLY96
E	GLN166
E	ARG168
E	GLU196
E	MET197
E	GLU198
E	ILE220
E	VAL221
E	PRO229
E	PO42051
E	HOH2066
F	HIS8

site_id	DC6
Number of Residues	15
Details	BINDING SITE FOR RESIDUE THM F 2062

Chain	Residue
E	HIS8
F	ARG91
F	THR94
F	GLY96
F	PHE162
F	GLN166
F	ARG168
F	TYR195
F	GLU196
F	MET197
F	GLU198
F	ILE220
F	VAL221
F	PO42061
F	HOH3022

site_id	DC7
Number of Residues	15
Details	BINDING SITE FOR RESIDUE THM G 2072

Chain	Residue
G	ILE69
G	THR94
G	THR95
G	GLY96
G	PHE162
G	GLN166
G	ARG168
G	GLU196
G	MET197
G	GLU198
G	ILE220
G	VAL221
G	HOH611
G	PO42071
H	HIS8

site_id	DC8
Number of Residues	16
Details	BINDING SITE FOR RESIDUE THM H 2082

Chain	Residue
G	HIS8
G	ARG48
H	ILE69
H	THR94
H	GLY96
H	PHE162
H	GLN166
H	ARG168
H	TYR195
H	GLU196
H	MET197
H	GLU198
H	ILE220
H	PRO229
H	HOH711
H	PO42081

site_id	DC9
Number of Residues	13
Details	BINDING SITE FOR RESIDUE THM I 2092

Chain	Residue
I	ILE69
I	THR94
I	THR95
I	GLY96
I	GLN166
I	ARG168
I	GLU196
I	MET197
I	GLU198
I	ILE220
I	HOH811
I	PO42091
J	HIS8

site_id	EC1
Number of Residues	13
Details	BINDING SITE FOR RESIDUE THM J 2102

Chain	Residue
I	HIS8
J	ILE69
J	THR94
J	GLY96
J	PHE162
J	GLN166
J	ARG168
J	GLU196
J	MET197
J	GLU198
J	ILE220
J	VAL221
J	PO42101

site_id	EC2
Number of Residues	14
Details	BINDING SITE FOR RESIDUE THM K 2112

Chain	Residue
K	ILE69
K	THR94
K	THR95
K	GLY96
K	PHE162
K	GLN166
K	ARG168
K	GLU196
K	MET197
K	GLU198
K	ILE220
K	HOH1011
K	PO42111
L	HIS8

site_id	EC3
Number of Residues	13
Details	BINDING SITE FOR RESIDUE THM L 2122

Chain	Residue
K	HIS8
L	THR94
L	GLY96
L	PHE162
L	GLN166
L	ARG168
L	GLU196
L	MET197
L	GLU198
L	ILE220
L	VAL221
L	PRO229
L	PO42121

site_id	EC4
Number of Residues	14
Details	BINDING SITE FOR RESIDUE THM M 2132

Chain	Residue
M	ILE69
M	THR94
M	GLY96
M	PHE162
M	GLN166
M	ARG168
M	TYR195
M	GLU196
M	MET197
M	GLU198
M	ILE220
M	HOH1211
M	PO42131
N	HIS8

site_id	EC5
Number of Residues	13
Details	BINDING SITE FOR RESIDUE THM N 2142

Chain	Residue
M	HIS8
N	ILE69
N	THR94
N	PHE162
N	GLN166
N	ARG168
N	GLU196
N	MET197
N	GLU198
N	ILE220
N	VAL221
N	HOH1311
N	PO42141

site_id	EC6
Number of Residues	15
Details	BINDING SITE FOR RESIDUE THM O 2152

Chain	Residue
O	ILE69
O	THR94
O	GLY96
O	PHE162
O	GLN166
O	ARG168
O	TYR195
O	GLU196
O	MET197
O	GLU198
O	ILE220
O	VAL221
O	HOH1411
O	PO42151
P	HIS8

site_id	EC7
Number of Residues	14
Details	BINDING SITE FOR RESIDUE THM P 2162

Chain	Residue
O	HIS8
P	THR94
P	GLY96
P	PHE162
P	GLN166
P	ARG168
P	GLU196
P	MET197
P	GLU198
P	ILE220
P	VAL221
P	PRO229
P	HOH1511
P	PO42161

site_id	EC8
Number of Residues	14
Details	BINDING SITE FOR RESIDUE THM Q 2172

Chain	Residue
Q	ILE69
Q	THR94
Q	GLY96
Q	PHE162
Q	GLN166
Q	ARG168
Q	TYR195
Q	GLU196
Q	MET197
Q	GLU198
Q	ILE220
Q	HOH1611
Q	PO42171
R	HIS8

site_id	EC9
Number of Residues	14
Details	BINDING SITE FOR RESIDUE THM R 2182

Chain	Residue
Q	HIS8
R	ILE69
R	THR94
R	THR95
R	GLY96
R	PHE162
R	GLN166
R	ARG168
R	GLU196
R	MET197
R	GLU198
R	ILE220
R	HOH1711
R	PO42181

Functional Information from PROSITE/UniProt

site_id	PS01232
Number of Residues	16
Details	PNP_UDP_1 Purine and other phosphorylases family 1 signature. StGIGgPStSIaveEL

Chain	Residue	Details
A	SER66-LEU81

Catalytic Information from CSA

site_id	CSA1
Number of Residues	3
Details	Annotated By Reference To The Literature 1t0u

Chain	Residue	Details
A	GLU80
A	HIS8
A	ARG223

site_id	CSA10
Number of Residues	3
Details	Annotated By Reference To The Literature 1t0u

Chain	Residue	Details
J	GLU80
J	HIS8
J	ARG223

site_id	CSA11
Number of Residues	3
Details	Annotated By Reference To The Literature 1t0u

Chain	Residue	Details
K	GLU80
K	HIS8
K	ARG223

site_id	CSA12
Number of Residues	3
Details	Annotated By Reference To The Literature 1t0u

Chain	Residue	Details
L	GLU80
L	HIS8
L	ARG223

site_id	CSA13
Number of Residues	3
Details	Annotated By Reference To The Literature 1t0u

Chain	Residue	Details
M	GLU80
M	HIS8
M	ARG223

site_id	CSA14
Number of Residues	3
Details	Annotated By Reference To The Literature 1t0u

Chain	Residue	Details
N	GLU80
N	HIS8
N	ARG223

site_id	CSA15
Number of Residues	3
Details	Annotated By Reference To The Literature 1t0u

Chain	Residue	Details
O	GLU80
O	HIS8
O	ARG223

site_id	CSA16
Number of Residues	3
Details	Annotated By Reference To The Literature 1t0u

Chain	Residue	Details
P	GLU80
P	HIS8
P	ARG223

site_id	CSA17
Number of Residues	3
Details	Annotated By Reference To The Literature 1t0u

Chain	Residue	Details
Q	GLU80
Q	HIS8
Q	ARG223

site_id	CSA18
Number of Residues	3
Details	Annotated By Reference To The Literature 1t0u

Chain	Residue	Details
R	GLU80
R	HIS8
R	ARG223

site_id	CSA2
Number of Residues	3
Details	Annotated By Reference To The Literature 1t0u

Chain	Residue	Details
B	GLU80
B	HIS8
B	ARG223

site_id	CSA3
Number of Residues	3
Details	Annotated By Reference To The Literature 1t0u

Chain	Residue	Details
C	GLU80
C	HIS8
C	ARG223

site_id	CSA4
Number of Residues	3
Details	Annotated By Reference To The Literature 1t0u

Chain	Residue	Details
D	GLU80
D	HIS8
D	ARG223

site_id	CSA5
Number of Residues	3
Details	Annotated By Reference To The Literature 1t0u

Chain	Residue	Details
E	GLU80
E	HIS8
E	ARG223

site_id	CSA6
Number of Residues	3
Details	Annotated By Reference To The Literature 1t0u

Chain	Residue	Details
F	GLU80
F	HIS8
F	ARG223

site_id	CSA7
Number of Residues	3
Details	Annotated By Reference To The Literature 1t0u

Chain	Residue	Details
G	GLU80
G	HIS8
G	ARG223

site_id	CSA8
Number of Residues	3
Details	Annotated By Reference To The Literature 1t0u

Chain	Residue	Details
H	GLU80
H	HIS8
H	ARG223

site_id	CSA9
Number of Residues	3
Details	Annotated By Reference To The Literature 1t0u

Chain	Residue	Details
I	GLU80
I	HIS8
I	ARG223

site_id	MCSA1
Number of Residues	4
Details	M-CSA 787

Chain	Residue	Details
A	HIS8	proton acceptor, proton donor
A	GLU80	electrostatic stabiliser, polar interaction
A	ARG168	proton acceptor, proton donor
A	ARG223	electrostatic stabiliser, polar interaction

site_id	MCSA10
Number of Residues	4
Details	M-CSA 787

Chain	Residue	Details
J	HIS8	proton acceptor, proton donor
J	GLU80	electrostatic stabiliser, polar interaction
J	ARG168	proton acceptor, proton donor
J	ARG223	electrostatic stabiliser, polar interaction

site_id	MCSA11
Number of Residues	4
Details	M-CSA 787

Chain	Residue	Details
K	HIS8	proton acceptor, proton donor
K	GLU80	electrostatic stabiliser, polar interaction
K	ARG168	proton acceptor, proton donor
K	ARG223	electrostatic stabiliser, polar interaction

site_id	MCSA12
Number of Residues	4
Details	M-CSA 787

Chain	Residue	Details
L	HIS8	proton acceptor, proton donor
L	GLU80	electrostatic stabiliser, polar interaction
L	ARG168	proton acceptor, proton donor
L	ARG223	electrostatic stabiliser, polar interaction

site_id	MCSA13
Number of Residues	4
Details	M-CSA 787

Chain	Residue	Details
M	HIS8	proton acceptor, proton donor
M	GLU80	electrostatic stabiliser, polar interaction
M	ARG168	proton acceptor, proton donor
M	ARG223	electrostatic stabiliser, polar interaction

site_id	MCSA14
Number of Residues	4
Details	M-CSA 787

Chain	Residue	Details
N	HIS8	proton acceptor, proton donor
N	GLU80	electrostatic stabiliser, polar interaction
N	ARG168	proton acceptor, proton donor
N	ARG223	electrostatic stabiliser, polar interaction

site_id	MCSA15
Number of Residues	4
Details	M-CSA 787

Chain	Residue	Details
O	HIS8	proton acceptor, proton donor
O	GLU80	electrostatic stabiliser, polar interaction
O	ARG168	proton acceptor, proton donor
O	ARG223	electrostatic stabiliser, polar interaction

site_id	MCSA16
Number of Residues	4
Details	M-CSA 787

Chain	Residue	Details
P	HIS8	proton acceptor, proton donor
P	GLU80	electrostatic stabiliser, polar interaction
P	ARG168	proton acceptor, proton donor
P	ARG223	electrostatic stabiliser, polar interaction

site_id	MCSA17
Number of Residues	4
Details	M-CSA 787

Chain	Residue	Details
Q	HIS8	proton acceptor, proton donor
Q	GLU80	electrostatic stabiliser, polar interaction
Q	ARG168	proton acceptor, proton donor
Q	ARG223	electrostatic stabiliser, polar interaction

site_id	MCSA18
Number of Residues	4
Details	M-CSA 787

Chain	Residue	Details
R	HIS8	proton acceptor, proton donor
R	GLU80	electrostatic stabiliser, polar interaction
R	ARG168	proton acceptor, proton donor
R	ARG223	electrostatic stabiliser, polar interaction

site_id	MCSA2
Number of Residues	4
Details	M-CSA 787

Chain	Residue	Details
B	HIS8	proton acceptor, proton donor
B	GLU80	electrostatic stabiliser, polar interaction
B	ARG168	proton acceptor, proton donor
B	ARG223	electrostatic stabiliser, polar interaction

site_id	MCSA3
Number of Residues	4
Details	M-CSA 787

Chain	Residue	Details
C	HIS8	proton acceptor, proton donor
C	GLU80	electrostatic stabiliser, polar interaction
C	ARG168	proton acceptor, proton donor
C	ARG223	electrostatic stabiliser, polar interaction

site_id	MCSA4
Number of Residues	4
Details	M-CSA 787

Chain	Residue	Details
D	HIS8	proton acceptor, proton donor
D	GLU80	electrostatic stabiliser, polar interaction
D	ARG168	proton acceptor, proton donor
D	ARG223	electrostatic stabiliser, polar interaction

site_id	MCSA5
Number of Residues	4
Details	M-CSA 787

Chain	Residue	Details
E	HIS8	proton acceptor, proton donor
E	GLU80	electrostatic stabiliser, polar interaction
E	ARG168	proton acceptor, proton donor
E	ARG223	electrostatic stabiliser, polar interaction

site_id	MCSA6
Number of Residues	4
Details	M-CSA 787

Chain	Residue	Details
F	HIS8	proton acceptor, proton donor
F	GLU80	electrostatic stabiliser, polar interaction
F	ARG168	proton acceptor, proton donor
F	ARG223	electrostatic stabiliser, polar interaction

site_id	MCSA7
Number of Residues	4
Details	M-CSA 787

Chain	Residue	Details
G	HIS8	proton acceptor, proton donor
G	GLU80	electrostatic stabiliser, polar interaction
G	ARG168	proton acceptor, proton donor
G	ARG223	electrostatic stabiliser, polar interaction

site_id	MCSA8
Number of Residues	4
Details	M-CSA 787

Chain	Residue	Details
H	HIS8	proton acceptor, proton donor
H	GLU80	electrostatic stabiliser, polar interaction
H	ARG168	proton acceptor, proton donor
H	ARG223	electrostatic stabiliser, polar interaction

site_id	MCSA9
Number of Residues	4
Details	M-CSA 787

Chain	Residue	Details
I	HIS8	proton acceptor, proton donor
I	GLU80	electrostatic stabiliser, polar interaction
I	ARG168	proton acceptor, proton donor
I	ARG223	electrostatic stabiliser, polar interaction

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)