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1RRG

NON-MYRISTOYLATED RAT ADP-RIBOSYLATION FACTOR-1 COMPLEXED WITH GDP, DIMERIC CRYSTAL FORM

Functional Information from GO Data
ChainGOidnamespacecontents
A0000139cellular_componentGolgi membrane
A0000287molecular_functionmagnesium ion binding
A0002090biological_processregulation of receptor internalization
A0003924molecular_functionGTPase activity
A0005515molecular_functionprotein binding
A0005525molecular_functionGTP binding
A0005770cellular_componentlate endosome
A0005778cellular_componentperoxisomal membrane
A0005794cellular_componentGolgi apparatus
A0005802cellular_componenttrans-Golgi network
A0005829cellular_componentcytosol
A0005886cellular_componentplasma membrane
A0006878biological_processintracellular copper ion homeostasis
A0006886biological_processintracellular protein transport
A0007015biological_processactin filament organization
A0012505cellular_componentendomembrane system
A0014069cellular_componentpostsynaptic density
A0015031biological_processprotein transport
A0016020cellular_componentmembrane
A0016192biological_processvesicle-mediated transport
A0016787molecular_functionhydrolase activity
A0019003molecular_functionGDP binding
A0019904molecular_functionprotein domain specific binding
A0030017cellular_componentsarcomere
A0030137cellular_componentCOPI-coated vesicle
A0031252cellular_componentcell leading edge
A0032991cellular_componentprotein-containing complex
A0034315biological_processregulation of Arp2/3 complex-mediated actin nucleation
A0034379biological_processvery-low-density lipoprotein particle assembly
A0043005cellular_componentneuron projection
A0045202cellular_componentsynapse
A0045807biological_processpositive regulation of endocytosis
A0045956biological_processpositive regulation of calcium ion-dependent exocytosis
A0050714biological_processpositive regulation of protein secretion
A0055108biological_processGolgi to transport vesicle transport
A0060292biological_processlong-term synaptic depression
A0060999biological_processpositive regulation of dendritic spine development
A0070142biological_processsynaptic vesicle budding
A0097061biological_processdendritic spine organization
A0097212biological_processlysosomal membrane organization
A0098974biological_processpostsynaptic actin cytoskeleton organization
A0098978cellular_componentglutamatergic synapse
A1902307biological_processpositive regulation of sodium ion transmembrane transport
A1902824biological_processpositive regulation of late endosome to lysosome transport
A1902953biological_processpositive regulation of ER to Golgi vesicle-mediated transport
A1903725biological_processregulation of phospholipid metabolic process
A1990386biological_processmitotic cleavage furrow ingression
A1990583molecular_functionphospholipase D activator activity
B0000139cellular_componentGolgi membrane
B0000287molecular_functionmagnesium ion binding
B0002090biological_processregulation of receptor internalization
B0003924molecular_functionGTPase activity
B0005515molecular_functionprotein binding
B0005525molecular_functionGTP binding
B0005770cellular_componentlate endosome
B0005778cellular_componentperoxisomal membrane
B0005794cellular_componentGolgi apparatus
B0005802cellular_componenttrans-Golgi network
B0005829cellular_componentcytosol
B0005886cellular_componentplasma membrane
B0006878biological_processintracellular copper ion homeostasis
B0006886biological_processintracellular protein transport
B0007015biological_processactin filament organization
B0012505cellular_componentendomembrane system
B0014069cellular_componentpostsynaptic density
B0015031biological_processprotein transport
B0016020cellular_componentmembrane
B0016192biological_processvesicle-mediated transport
B0016787molecular_functionhydrolase activity
B0019003molecular_functionGDP binding
B0019904molecular_functionprotein domain specific binding
B0030017cellular_componentsarcomere
B0030137cellular_componentCOPI-coated vesicle
B0031252cellular_componentcell leading edge
B0032991cellular_componentprotein-containing complex
B0034315biological_processregulation of Arp2/3 complex-mediated actin nucleation
B0034379biological_processvery-low-density lipoprotein particle assembly
B0043005cellular_componentneuron projection
B0045202cellular_componentsynapse
B0045807biological_processpositive regulation of endocytosis
B0045956biological_processpositive regulation of calcium ion-dependent exocytosis
B0050714biological_processpositive regulation of protein secretion
B0055108biological_processGolgi to transport vesicle transport
B0060292biological_processlong-term synaptic depression
B0060999biological_processpositive regulation of dendritic spine development
B0070142biological_processsynaptic vesicle budding
B0097061biological_processdendritic spine organization
B0097212biological_processlysosomal membrane organization
B0098974biological_processpostsynaptic actin cytoskeleton organization
B0098978cellular_componentglutamatergic synapse
B1902307biological_processpositive regulation of sodium ion transmembrane transport
B1902824biological_processpositive regulation of late endosome to lysosome transport
B1902953biological_processpositive regulation of ER to Golgi vesicle-mediated transport
B1903725biological_processregulation of phospholipid metabolic process
B1990386biological_processmitotic cleavage furrow ingression
B1990583molecular_functionphospholipase D activator activity
Functional Information from PDB Data
site_idAC1
Number of Residues6
DetailsBINDING SITE FOR RESIDUE MG A 182
ChainResidue
ATHR31
AGLU54
AGDP183
AHOH246
AHOH253
BHOH223

site_idAC2
Number of Residues5
DetailsBINDING SITE FOR RESIDUE MG B 182
ChainResidue
BHOH259
BHOH260
BTHR31
BGDP183
BHOH254

site_idAC3
Number of Residues22
DetailsBINDING SITE FOR RESIDUE GDP A 183
ChainResidue
AALA27
AALA28
AGLY29
ALYS30
ATHR31
ATHR32
AASN126
ALYS127
AASP129
ALEU130
ACYS159
AALA160
ATHR161
AMG182
AHOH189
AHOH221
AHOH226
AHOH230
AHOH246
AHOH253
BGLY50
BASN52

site_idAC4
Number of Residues22
DetailsBINDING SITE FOR RESIDUE GDP B 183
ChainResidue
AILE49
AGLY50
BASP26
BALA27
BALA28
BGLY29
BLYS30
BTHR31
BTHR32
BASN126
BLYS127
BASP129
BLEU130
BCYS159
BALA160
BMG182
BHOH193
BHOH213
BHOH219
BHOH225
BHOH254
BHOH260

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues4
DetailsBINDING: BINDING => ECO:0000269|PubMed:7552752, ECO:0007744|PDB:1RRF, ECO:0007744|PDB:1RRG
ChainResidueDetails
ALEU25
ALYS127
BLEU25
BLYS127

site_idSWS_FT_FI2
Number of Residues2
DetailsBINDING: BINDING => ECO:0000269|PubMed:7552752, ECO:0007744|PDB:1RRG
ChainResidueDetails
ATHR161
BTHR161

site_idSWS_FT_FI3
Number of Residues2
DetailsMOD_RES: N-acetylglycine; alternate => ECO:0000250|UniProtKB:P84077
ChainResidueDetails
AASN3
BASN3

site_idSWS_FT_FI4
Number of Residues2
DetailsLIPID: N-myristoyl glycine; alternate => ECO:0000250|UniProtKB:P84077
ChainResidueDetails
AASN3
BASN3

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PDB entries from 2024-11-06

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