1RNH

STRUCTURE OF RIBONUCLEASE H PHASED AT 2 ANGSTROMS RESOLUTION BY MAD ANALYSIS OF THE SELENOMETHIONYL PROTEIN

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000287	molecular_function	magnesium ion binding
A	0003676	molecular_function	nucleic acid binding
A	0004518	molecular_function	nuclease activity
A	0004519	molecular_function	endonuclease activity
A	0004523	molecular_function	RNA-DNA hybrid ribonuclease activity
A	0005515	molecular_function	protein binding
A	0005737	cellular_component	cytoplasm
A	0006401	biological_process	RNA catabolic process
A	0016787	molecular_function	hydrolase activity
A	0043137	biological_process	DNA replication, removal of RNA primer
A	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 A 156

Chain	Residue
A	THR43
A	ASN45
A	LYS99
A	ASN100
A	HOH204
A	HOH309

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	BINDING: BINDING => ECO:0000269|PubMed:1311386

Chain	Residue	Details
A	ASP10
A	GLU48
A	ASP70
A	ASP134

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Catalytic Information from CSA

site_id	MCSA1
Number of Residues	6
Details	M-CSA 163

Chain	Residue	Details
A	LEU14	metal ligand
A	GLY15	metal ligand
A	LYS60	increase acidity, increase basicity, unknown
A	ILE82	metal ligand
A	LEU136	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor, unknown
A	LEU146	increase acidity, metal ligand, proton acceptor, proton donor

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