Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004222 | molecular_function | metalloendopeptidase activity |
A | 0006508 | biological_process | proteolysis |
A | 0008237 | molecular_function | metallopeptidase activity |
A | 0008270 | molecular_function | zinc ion binding |
A | 0031012 | cellular_component | extracellular matrix |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE ZN A 500 |
Chain | Residue |
A | HIS246 |
A | HIS250 |
A | HIS256 |
A | BAT800 |
site_id | AC2 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE ZN A 501 |
Chain | Residue |
A | HIS193 |
A | ASP195 |
A | HIS208 |
A | HIS221 |
site_id | AC3 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE CA A 502 |
Chain | Residue |
A | GLY201 |
A | GLY203 |
A | PHE205 |
A | ASP223 |
A | GLU226 |
A | ASP200 |
site_id | AC4 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE CA A 504 |
Chain | Residue |
A | ASP183 |
A | GLY215 |
A | ILE216 |
A | GLY217 |
A | ASP219 |
A | HOH1076 |
site_id | AC5 |
Number of Residues | 16 |
Details | BINDING SITE FOR RESIDUE BAT A 800 |
Chain | Residue |
A | GLY194 |
A | GLY204 |
A | PHE205 |
A | LEU206 |
A | ALA207 |
A | HIS246 |
A | GLU247 |
A | HIS250 |
A | HIS256 |
A | PRO260 |
A | PRO266 |
A | PHE267 |
A | TYR268 |
A | ZN500 |
A | HOH1000 |
A | HOH1029 |
Functional Information from PROSITE/UniProt
site_id | PS00142 |
Number of Residues | 10 |
Details | ZINC_PROTEASE Neutral zinc metallopeptidases, zinc-binding region signature. VAVHELGHAL |
Chain | Residue | Details |
A | VAL243-LEU252 | |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 1 |
Details | ACT_SITE: |
Chain | Residue | Details |
A | GLU247 | |
Chain | Residue | Details |
A | ASP183 | |
A | ASP219 | |
A | HIS221 | |
A | ASP223 | |
A | GLU226 | |
A | HIS246 | |
A | HIS250 | |
A | HIS256 | |
A | HIS193 | |
A | ASP195 | |
A | ASP200 | |
A | GLY201 | |
A | GLY203 | |
A | PHE205 | |
A | HIS208 | |
A | GLY215 | |
site_id | SWS_FT_FI3 |
Number of Residues | 1 |
Details | BINDING: |
Chain | Residue | Details |
A | GLY217 | |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1hfs |
Chain | Residue | Details |
A | MET264 | |
A | GLU247 | |
site_id | CSA2 |
Number of Residues | 1 |
Details | Annotated By Reference To The Literature 1hfs |
Chain | Residue | Details |
A | GLU247 | |