Functional Information from GO Data
| Chain | GOid | namespace | contents |
| B | 0004252 | molecular_function | serine-type endopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 B 201 |
| Chain | Residue |
| B | HOH108 |
| B | HOH115 |
| B | HOH154 |
| B | PRO595 |
| B | ARG789 |
| B | ASN790 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 B 202 |
| Chain | Residue |
| B | GLN721 |
| B | SER722 |
| B | HOH103 |
| B | HIS629 |
| B | ARG644 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B 203 |
| Chain | Residue |
| B | HOH134 |
| B | SER636 |
| B | ARG637 |
| B | LYS651 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 B 204 |
| Chain | Residue |
| B | ARG644 |
| B | LYS661 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 B 205 |
| Chain | Residue |
| B | HOH112 |
| B | SO4207 |
| B | HIS571 |
| B | GLU627 |
| B | LYS661 |
| B | ARG719 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B 206 |
| Chain | Residue |
| B | HOH147 |
| B | ARG712 |
| B | TYR713 |
| B | GLU714 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 B 207 |
| Chain | Residue |
| B | HOH10 |
| B | HOH105 |
| B | SO4205 |
| B | PRO570 |
| B | ARG719 |
| site_id | AC8 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 B 208 |
| Chain | Residue |
| B | HOH55 |
| B | HOH55 |
| B | ARG677 |
| B | PRO703 |
| B | HIS729 |
| B | HIS729 |
| B | LEU730 |
| B | ALA731 |
Functional Information from PROSITE/UniProt
| site_id | PS00134 |
| Number of Residues | 6 |
| Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. LTAAHC |
| Chain | Residue | Details |
| B | LEU599-CYS604 | |
| site_id | PS00135 |
| Number of Residues | 12 |
| Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. DScqGDSGGPLV |
| Chain | Residue | Details |
| B | ASP735-VAL746 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | Active site: {"description":"Charge relay system"} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Site: {"description":"Cleavage; by plasminogen activator"} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"9201958","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1a0j |
| Chain | Residue | Details |
| B | HIS603 | |
| B | ASP646 | |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1a0j |
| Chain | Residue | Details |
| B | SER741 | |
| B | GLY742 | |
| site_id | CSA3 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1a0j |
| Chain | Residue | Details |
| B | SER741 | |
| B | GLY739 | |
| site_id | CSA4 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1a0j |
| Chain | Residue | Details |
| B | HIS603 | |
| B | SER741 | |
| B | ASP646 | |
| site_id | CSA5 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1a0j |
| Chain | Residue | Details |
| B | HIS603 | |
| B | SER741 | |
| B | ASP646 | |
| B | GLY742 | |
| site_id | CSA6 |
| Number of Residues | 7 |
| Details | Annotated By Reference To The Literature 1a0j |
| Chain | Residue | Details |
| B | CYS737 | |
| B | HIS603 | |
| B | SER741 | |
| B | ASP740 | |
| B | ASP646 | |
| B | GLY739 | |
| B | GLN738 | |
| site_id | CSA7 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1a0j |
| Chain | Residue | Details |
| B | HIS603 | |
| B | SER741 | |
| B | GLY739 | |
| B | ASP646 | |
| site_id | MCSA1 |
| Number of Residues | 4 |
| Details | M-CSA 425 |
