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1RJ9

Structure of the heterodimer of the conserved GTPase domains of the Signal Recognition Particle (Ffh) and Its Receptor (FtsY)

Functional Information from GO Data
ChainGOidnamespacecontents
A0003924molecular_functionGTPase activity
A0005047molecular_functionsignal recognition particle binding
A0005515molecular_functionprotein binding
A0005525molecular_functionGTP binding
A0005737cellular_componentcytoplasm
A0005886cellular_componentplasma membrane
A0006605biological_processprotein targeting
A0006612biological_processprotein targeting to membrane
A0006614biological_processSRP-dependent cotranslational protein targeting to membrane
A0016020cellular_componentmembrane
A0016787molecular_functionhydrolase activity
A0016887molecular_functionATP hydrolysis activity
B0003924molecular_functionGTPase activity
B0005525molecular_functionGTP binding
B0006614biological_processSRP-dependent cotranslational protein targeting to membrane
B0016887molecular_functionATP hydrolysis activity
B0048500cellular_componentsignal recognition particle
Functional Information from PDB Data
site_idAC1
Number of Residues5
DetailsBINDING SITE FOR RESIDUE MG A 501
ChainResidue
ATHR116
AGCP500
AHOH701
AHOH702
AHOH703

site_idAC2
Number of Residues5
DetailsBINDING SITE FOR RESIDUE MG B 601
ChainResidue
BHOH706
BTHR112
BGCP600
BHOH704
BHOH705

site_idAC3
Number of Residues27
DetailsBINDING SITE FOR RESIDUE GCP A 500
ChainResidue
AASN111
AGLY112
AVAL113
AGLY114
ALYS115
ATHR116
ATHR117
ALYS121
AASP139
AARG142
AGLN148
AGLY194
ALYS256
AASP258
AGLY281
AVAL282
AGLY283
AGLU284
AMG501
AHOH702
AHOH713
AHOH722
AHOH749
BGLN107
BARG138
BGCP600
BHOH718

site_idAC4
Number of Residues29
DetailsBINDING SITE FOR RESIDUE GCP B 600
ChainResidue
AASN111
AARG142
ALEU196
AGCP500
BGLN107
BGLY108
BSER109
BGLY110
BLYS111
BTHR112
BTHR113
BLYS117
BASP135
BARG138
BGLN144
BGLY190
BLYS246
BASP248
BGLY271
BVAL272
BSER273
BGLU274
BMG601
BHOH705
BHOH707
BHOH718
BHOH719
BHOH727
BHOH760

Functional Information from PROSITE/UniProt
site_idPS00300
Number of Residues14
DetailsSRP54 SRP54-type proteins GTP-binding domain signature. PIyFAGVSEkPegL
ChainResidueDetails
BPRO266-LEU279
APRO276-LEU289

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues3
DetailsBINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00306
ChainResidueDetails
BLEU106
BTHR188
BLYS246

226707

PDB entries from 2024-10-30

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