1RFX
Crystal Structure of resisitin
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005179 | molecular_function | hormone activity |
| A | 0005576 | cellular_component | extracellular region |
| A | 0005615 | cellular_component | extracellular space |
| A | 0007165 | biological_process | signal transduction |
| A | 0010714 | biological_process | positive regulation of collagen metabolic process |
| A | 0014911 | biological_process | positive regulation of smooth muscle cell migration |
| A | 0032868 | biological_process | response to insulin |
| A | 0045444 | biological_process | fat cell differentiation |
| A | 0048661 | biological_process | positive regulation of smooth muscle cell proliferation |
| A | 0050806 | biological_process | positive regulation of synaptic transmission |
| A | 2000252 | biological_process | negative regulation of feeding behavior |
| A | 2000872 | biological_process | positive regulation of progesterone secretion |
| B | 0005179 | molecular_function | hormone activity |
| B | 0005576 | cellular_component | extracellular region |
| B | 0005615 | cellular_component | extracellular space |
| B | 0007165 | biological_process | signal transduction |
| B | 0010714 | biological_process | positive regulation of collagen metabolic process |
| B | 0014911 | biological_process | positive regulation of smooth muscle cell migration |
| B | 0032868 | biological_process | response to insulin |
| B | 0045444 | biological_process | fat cell differentiation |
| B | 0048661 | biological_process | positive regulation of smooth muscle cell proliferation |
| B | 0050806 | biological_process | positive regulation of synaptic transmission |
| B | 2000252 | biological_process | negative regulation of feeding behavior |
| B | 2000872 | biological_process | positive regulation of progesterone secretion |
| C | 0005179 | molecular_function | hormone activity |
| C | 0005576 | cellular_component | extracellular region |
| C | 0005615 | cellular_component | extracellular space |
| C | 0007165 | biological_process | signal transduction |
| C | 0010714 | biological_process | positive regulation of collagen metabolic process |
| C | 0014911 | biological_process | positive regulation of smooth muscle cell migration |
| C | 0032868 | biological_process | response to insulin |
| C | 0045444 | biological_process | fat cell differentiation |
| C | 0048661 | biological_process | positive regulation of smooth muscle cell proliferation |
| C | 0050806 | biological_process | positive regulation of synaptic transmission |
| C | 2000252 | biological_process | negative regulation of feeding behavior |
| C | 2000872 | biological_process | positive regulation of progesterone secretion |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL A 501 |
| Chain | Residue |
| A | SER94 |
| B | PEG9180 |
| C | ASP66 |
| C | GLN76 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CL B 502 |
| Chain | Residue |
| B | HOH9212 |
| A | ARG86 |
| A | HOH612 |
| B | ILE67 |
| B | GLU69 |
| B | GLU70 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL B 503 |
| Chain | Residue |
| B | ASN30 |
| B | HOH9199 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL C 504 |
| Chain | Residue |
| A | HOH637 |
| C | ARG68 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL A 505 |
| Chain | Residue |
| A | ILE67 |
| A | HOH647 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL B 506 |
| Chain | Residue |
| B | ILE28 |
| C | ALA27 |
| site_id | AC7 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL A 507 |
| Chain | Residue |
| A | SER94 |
| C | HIS74 |
| site_id | AC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL A 508 |
| Chain | Residue |
| A | ASP13 |
| B | LYS15 |
| site_id | AC9 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL A 509 |
| Chain | Residue |
| A | LEU44 |
| A | ARG68 |
| site_id | BC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL C 510 |
| Chain | Residue |
| A | HOH669 |
| C | GLU49 |
| C | HOH656 |
| site_id | BC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL B 511 |
| Chain | Residue |
| B | ARG68 |
| B | HOH9218 |
| site_id | BC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ACT A 601 |
| Chain | Residue |
| A | ASP66 |
| A | ARG68 |
| A | HIS74 |
| A | HOH677 |
| site_id | BC4 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE ACT A 602 |
| Chain | Residue |
| A | THR37 |
| A | ARG86 |
| A | HOH612 |
| A | HOH679 |
| B | ASN34 |
| B | LYS89 |
| B | GLN91 |
| B | HOH9239 |
| site_id | BC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ACT B 603 |
| Chain | Residue |
| B | GLY32 |
| B | LEU33 |
| B | HOH9188 |
| B | HOH9189 |
| C | GLY50 |
| C | THR51 |
| site_id | BC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ACT B 604 |
| Chain | Residue |
| B | GLY63 |
| B | SER64 |
| B | TRP65 |
| site_id | BC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ACT C 605 |
| Chain | Residue |
| C | LYS43 |
| C | HIS74 |
| C | HOH649 |
| site_id | BC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE ACT C 606 |
| Chain | Residue |
| B | LYS71 |
| C | HOH652 |
| site_id | BC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ACT A 607 |
| Chain | Residue |
| A | PRO7 |
| A | ALA11 |
| A | LYS14 |
| A | HOH635 |
| A | HOH656 |
| site_id | CC1 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE PGE B 9181 |
| Chain | Residue |
| A | PRO48 |
| A | LYS89 |
| B | VAL38 |
| B | SER40 |
| B | ARG41 |
| B | SER46 |
| B | HOH9182 |
| B | HOH9211 |
| B | HOH9235 |
| site_id | CC2 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE PEG B 9180 |
| Chain | Residue |
| A | GLN91 |
| A | VAL92 |
| A | CL501 |
| B | THR37 |
| B | SER39 |
| B | TRP82 |
| B | ALA84 |
| B | HOH9241 |
| C | TRP65 |
| C | ASP66 |
