1RF4
Structural Studies of Streptococcus pneumoniae EPSP Synthase, Tetrahedral intermediate Bound State
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0003824 | molecular_function | catalytic activity |
A | 0003866 | molecular_function | 3-phosphoshikimate 1-carboxyvinyltransferase activity |
A | 0005515 | molecular_function | protein binding |
A | 0005737 | cellular_component | cytoplasm |
A | 0008652 | biological_process | amino acid biosynthetic process |
A | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
A | 0009423 | biological_process | chorismate biosynthetic process |
A | 0016740 | molecular_function | transferase activity |
A | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
B | 0003824 | molecular_function | catalytic activity |
B | 0003866 | molecular_function | 3-phosphoshikimate 1-carboxyvinyltransferase activity |
B | 0005515 | molecular_function | protein binding |
B | 0005737 | cellular_component | cytoplasm |
B | 0008652 | biological_process | amino acid biosynthetic process |
B | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
B | 0009423 | biological_process | chorismate biosynthetic process |
B | 0016740 | molecular_function | transferase activity |
B | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
C | 0003824 | molecular_function | catalytic activity |
C | 0003866 | molecular_function | 3-phosphoshikimate 1-carboxyvinyltransferase activity |
C | 0005515 | molecular_function | protein binding |
C | 0005737 | cellular_component | cytoplasm |
C | 0008652 | biological_process | amino acid biosynthetic process |
C | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
C | 0009423 | biological_process | chorismate biosynthetic process |
C | 0016740 | molecular_function | transferase activity |
C | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
D | 0003824 | molecular_function | catalytic activity |
D | 0003866 | molecular_function | 3-phosphoshikimate 1-carboxyvinyltransferase activity |
D | 0005515 | molecular_function | protein binding |
D | 0005737 | cellular_component | cytoplasm |
D | 0008652 | biological_process | amino acid biosynthetic process |
D | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
D | 0009423 | biological_process | chorismate biosynthetic process |
D | 0016740 | molecular_function | transferase activity |
D | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 23 |
Details | BINDING SITE FOR RESIDUE SPQ A 1451 |
Chain | Residue |
A | LYS20 |
A | ARG193 |
A | ASP312 |
A | LYS339 |
A | GLU340 |
A | ARG343 |
A | HIS384 |
A | ARG385 |
A | HOH1453 |
A | HOH1456 |
A | HOH1472 |
A | SER21 |
A | HOH1481 |
A | HOH1505 |
A | HOH1581 |
A | HOH1658 |
A | ARG25 |
A | GLY92 |
A | THR93 |
A | ARG120 |
A | SER166 |
A | ALA167 |
A | GLN168 |
site_id | AC2 |
Number of Residues | 22 |
Details | BINDING SITE FOR RESIDUE SPQ B 1551 |
Chain | Residue |
B | LYS20 |
B | SER21 |
B | ARG25 |
B | GLY92 |
B | THR93 |
B | ARG120 |
B | SER166 |
B | ALA167 |
B | GLN168 |
B | ARG193 |
B | ASP312 |
B | LYS339 |
B | GLU340 |
B | ARG343 |
B | HIS384 |
B | ARG385 |
B | HOH1560 |
B | HOH1593 |
B | HOH1601 |
B | HOH1602 |
B | HOH1617 |
B | HOH1682 |
site_id | AC3 |
Number of Residues | 24 |
Details | BINDING SITE FOR RESIDUE SPQ C 1651 |
Chain | Residue |
C | LYS20 |
C | SER21 |
C | ARG25 |
C | SER91 |
C | GLY92 |
C | THR93 |
C | ARG120 |
C | SER166 |
C | ALA167 |
C | GLN168 |
C | ARG193 |
C | ILE311 |
C | ASP312 |
C | LYS339 |
C | GLU340 |
C | ARG343 |
C | HIS384 |
C | ARG385 |
C | HOH1652 |
C | HOH1669 |
C | HOH1678 |
C | HOH1694 |
C | HOH1734 |
C | HOH1762 |
site_id | AC4 |
Number of Residues | 22 |
Details | BINDING SITE FOR RESIDUE SPQ D 1751 |
Chain | Residue |
D | LYS20 |
D | SER21 |
D | ARG25 |
D | GLY92 |
D | THR93 |
D | ARG120 |
D | SER166 |
D | ALA167 |
D | GLN168 |
D | ARG193 |
D | ASP312 |
D | LYS339 |
D | GLU340 |
D | ARG343 |
D | HIS384 |
D | ARG385 |
D | HOH1761 |
D | HOH1771 |
D | HOH1777 |
D | HOH1783 |
D | HOH1821 |
D | HOH1900 |
Functional Information from PROSITE/UniProt
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 4 |
Details | ACT_SITE: Proton acceptor => ECO:0000255|HAMAP-Rule:MF_00210, ECO:0000305|PubMed:14763973 |
Chain | Residue | Details |
A | ASP312 | |
B | ASP312 | |
C | ASP312 | |
D | ASP312 |
site_id | SWS_FT_FI2 |
Number of Residues | 24 |
Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00210 |
Chain | Residue | Details |
A | LYS20 | |
B | GLN168 | |
B | ARG343 | |
B | ARG385 | |
C | LYS20 | |
C | GLY92 | |
C | ARG120 | |
C | GLN168 | |
C | ARG343 | |
C | ARG385 | |
D | LYS20 | |
A | GLY92 | |
D | GLY92 | |
D | ARG120 | |
D | GLN168 | |
D | ARG343 | |
D | ARG385 | |
A | ARG120 | |
A | GLN168 | |
A | ARG343 | |
A | ARG385 | |
B | LYS20 | |
B | GLY92 | |
B | ARG120 |
site_id | SWS_FT_FI3 |
Number of Residues | 24 |
Details | BINDING: BINDING => ECO:0000269|PubMed:14763973, ECO:0007744|PDB:1RF6 |
Chain | Residue | Details |
A | SER21 | |
B | ALA167 | |
B | ASP312 | |
B | LYS339 | |
C | SER21 | |
C | ARG25 | |
C | SER166 | |
C | ALA167 | |
C | ASP312 | |
C | LYS339 | |
D | SER21 | |
A | ARG25 | |
D | ARG25 | |
D | SER166 | |
D | ALA167 | |
D | ASP312 | |
D | LYS339 | |
A | SER166 | |
A | ALA167 | |
A | ASP312 | |
A | LYS339 | |
B | SER21 | |
B | ARG25 | |
B | SER166 |