1RF4
Structural Studies of Streptococcus pneumoniae EPSP Synthase, Tetrahedral intermediate Bound State
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0003866 | molecular_function | 3-phosphoshikimate 1-carboxyvinyltransferase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0008652 | biological_process | amino acid biosynthetic process |
| A | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| A | 0009423 | biological_process | chorismate biosynthetic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0003866 | molecular_function | 3-phosphoshikimate 1-carboxyvinyltransferase activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0008652 | biological_process | amino acid biosynthetic process |
| B | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| B | 0009423 | biological_process | chorismate biosynthetic process |
| B | 0016740 | molecular_function | transferase activity |
| B | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
| C | 0003824 | molecular_function | catalytic activity |
| C | 0003866 | molecular_function | 3-phosphoshikimate 1-carboxyvinyltransferase activity |
| C | 0005515 | molecular_function | protein binding |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0008652 | biological_process | amino acid biosynthetic process |
| C | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| C | 0009423 | biological_process | chorismate biosynthetic process |
| C | 0016740 | molecular_function | transferase activity |
| C | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
| D | 0003824 | molecular_function | catalytic activity |
| D | 0003866 | molecular_function | 3-phosphoshikimate 1-carboxyvinyltransferase activity |
| D | 0005515 | molecular_function | protein binding |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0008652 | biological_process | amino acid biosynthetic process |
| D | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| D | 0009423 | biological_process | chorismate biosynthetic process |
| D | 0016740 | molecular_function | transferase activity |
| D | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE SPQ A 1451 |
| Chain | Residue |
| A | LYS20 |
| A | ARG193 |
| A | ASP312 |
| A | LYS339 |
| A | GLU340 |
| A | ARG343 |
| A | HIS384 |
| A | ARG385 |
| A | HOH1453 |
| A | HOH1456 |
| A | HOH1472 |
| A | SER21 |
| A | HOH1481 |
| A | HOH1505 |
| A | HOH1581 |
| A | HOH1658 |
| A | ARG25 |
| A | GLY92 |
| A | THR93 |
| A | ARG120 |
| A | SER166 |
| A | ALA167 |
| A | GLN168 |
| site_id | AC2 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE SPQ B 1551 |
| Chain | Residue |
| B | LYS20 |
| B | SER21 |
| B | ARG25 |
| B | GLY92 |
| B | THR93 |
| B | ARG120 |
| B | SER166 |
| B | ALA167 |
| B | GLN168 |
| B | ARG193 |
| B | ASP312 |
| B | LYS339 |
| B | GLU340 |
| B | ARG343 |
| B | HIS384 |
| B | ARG385 |
| B | HOH1560 |
| B | HOH1593 |
| B | HOH1601 |
| B | HOH1602 |
| B | HOH1617 |
| B | HOH1682 |
| site_id | AC3 |
| Number of Residues | 24 |
| Details | BINDING SITE FOR RESIDUE SPQ C 1651 |
| Chain | Residue |
| C | LYS20 |
| C | SER21 |
| C | ARG25 |
| C | SER91 |
| C | GLY92 |
| C | THR93 |
| C | ARG120 |
| C | SER166 |
| C | ALA167 |
| C | GLN168 |
| C | ARG193 |
| C | ILE311 |
| C | ASP312 |
| C | LYS339 |
| C | GLU340 |
| C | ARG343 |
| C | HIS384 |
| C | ARG385 |
| C | HOH1652 |
| C | HOH1669 |
| C | HOH1678 |
| C | HOH1694 |
| C | HOH1734 |
| C | HOH1762 |
| site_id | AC4 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE SPQ D 1751 |
| Chain | Residue |
| D | LYS20 |
| D | SER21 |
| D | ARG25 |
| D | GLY92 |
| D | THR93 |
| D | ARG120 |
| D | SER166 |
| D | ALA167 |
| D | GLN168 |
| D | ARG193 |
| D | ASP312 |
| D | LYS339 |
| D | GLU340 |
| D | ARG343 |
| D | HIS384 |
| D | ARG385 |
| D | HOH1761 |
| D | HOH1771 |
| D | HOH1777 |
| D | HOH1783 |
| D | HOH1821 |
| D | HOH1900 |
Functional Information from PROSITE/UniProt
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"HAMAP-Rule","id":"MF_00210","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"14763973","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 24 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00210","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 24 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"14763973","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1RF6","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
