1RDA
CRYSTAL STRUCTURES OF RIBONUCLEASE HI ACTIVE SITE MUTANTS FROM ESCHERICHIA COLI
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0003676 | molecular_function | nucleic acid binding |
| A | 0004519 | molecular_function | endonuclease activity |
| A | 0004523 | molecular_function | RNA-DNA hybrid ribonuclease activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006401 | biological_process | RNA catabolic process |
| A | 0043137 | biological_process | DNA replication, removal of RNA primer |
| A | 0046872 | molecular_function | metal ion binding |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:1311386 |
| Chain | Residue | Details |
| A | ASN10 | |
| A | GLU48 | |
| A | ASP70 | |
| A | ASP134 |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 6 |
| Details | M-CSA 163 |
| Chain | Residue | Details |
| A | ASN10 | metal ligand |
| A | GLY11 | metal ligand |
| A | GLU48 | increase acidity, increase basicity, unknown |
| A | ASP70 | metal ligand |
| A | HIS124 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor, unknown |
| A | ASP134 | increase acidity, metal ligand, proton acceptor, proton donor |
