1R8H
Comparison of the structure and DNA binding properties of the E2 proteins from an oncogenic and a non-oncogenic human papillomavirus
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003700 | molecular_function | DNA-binding transcription factor activity |
| A | 0006275 | biological_process | regulation of DNA replication |
| A | 0006355 | biological_process | regulation of DNA-templated transcription |
| A | 0042025 | cellular_component | host cell nucleus |
| B | 0003677 | molecular_function | DNA binding |
| B | 0003700 | molecular_function | DNA-binding transcription factor activity |
| B | 0006275 | biological_process | regulation of DNA replication |
| B | 0006355 | biological_process | regulation of DNA-templated transcription |
| B | 0042025 | cellular_component | host cell nucleus |
| C | 0003677 | molecular_function | DNA binding |
| C | 0003700 | molecular_function | DNA-binding transcription factor activity |
| C | 0006275 | biological_process | regulation of DNA replication |
| C | 0006355 | biological_process | regulation of DNA-templated transcription |
| C | 0042025 | cellular_component | host cell nucleus |
| D | 0003677 | molecular_function | DNA binding |
| D | 0003700 | molecular_function | DNA-binding transcription factor activity |
| D | 0006275 | biological_process | regulation of DNA replication |
| D | 0006355 | biological_process | regulation of DNA-templated transcription |
| D | 0042025 | cellular_component | host cell nucleus |
| E | 0003677 | molecular_function | DNA binding |
| E | 0003700 | molecular_function | DNA-binding transcription factor activity |
| E | 0006275 | biological_process | regulation of DNA replication |
| E | 0006355 | biological_process | regulation of DNA-templated transcription |
| E | 0042025 | cellular_component | host cell nucleus |
| F | 0003677 | molecular_function | DNA binding |
| F | 0003700 | molecular_function | DNA-binding transcription factor activity |
| F | 0006275 | biological_process | regulation of DNA replication |
| F | 0006355 | biological_process | regulation of DNA-templated transcription |
| F | 0042025 | cellular_component | host cell nucleus |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE PO4 D 501 |
| Chain | Residue |
| D | HIS318 |
| D | SER321 |
| D | LYS327 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PO4 E 502 |
| Chain | Residue |
| E | HIS318 |
| E | ALA320 |
| E | SER321 |
| E | LYS327 |
| E | HOH570 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PO4 D 503 |
| Chain | Residue |
| D | HIS306 |
| D | LYS349 |
| D | HOH528 |
| D | HOH531 |
| D | ARG302 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE PO4 D 504 |
| Chain | Residue |
| D | SER315 |
| D | THR316 |
| D | HOH544 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PO4 E 505 |
| Chain | Residue |
| E | ARG302 |
| E | HIS306 |
| E | LYS349 |
| E | HOH549 |
| E | HOH567 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PO4 E 506 |
| Chain | Residue |
| E | LYS297 |
| E | ARG300 |
| E | SER315 |
| E | THR316 |
| E | HOH545 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PO4 F 507 |
| Chain | Residue |
| F | LYS297 |
| F | ARG300 |
| F | SER315 |
| F | THR316 |
| F | HOH541 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PO4 A 508 |
| Chain | Residue |
| A | ARG302 |
| A | HIS306 |
| A | LYS349 |
| A | HOH569 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PO4 B 509 |
| Chain | Residue |
| B | LYS297 |
| B | ARG300 |
| B | SER315 |
| B | THR316 |
| B | HOH541 |
| site_id | BC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PO4 A 510 |
| Chain | Residue |
| A | ARG300 |
| A | SER315 |
| A | THR316 |
| A | HOH563 |
| site_id | BC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE PO4 B 511 |
| Chain | Residue |
| B | ARG302 |
| B | HIS306 |
| B | LYS349 |
| site_id | BC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PO4 C 512 |
| Chain | Residue |
| C | LYS297 |
| C | ARG300 |
| C | SER315 |
| C | THR316 |
| C | HOH551 |
| site_id | BC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PO4 F 513 |
| Chain | Residue |
| F | ARG302 |
| F | HIS306 |
| F | LYS349 |
| F | HOH537 |
| site_id | BC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PO4 C 514 |
| Chain | Residue |
| C | ARG302 |
| C | LYS305 |
| C | HIS306 |
| C | LYS349 |
